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Wrinkle reducing Botox to treat cancer

Université de Louvain in Brussels, Belgium researchers have found that Botox, a substance derived from botulinum toxin, used in cosmetic surgery to temporarily paralyze a muscle and reduce or eliminate wrinkles or frown lines, may be effective as an adjuvant drug to chemotherapy and radiation cancer treatments. The researchers injected Botulinum neurotoxin type A into tumors of mice, and were able to open up blood vessels that feed tumors, long enough to deliver more chemotherapy drugs directly into the tumors. Most research in the past has focused on closing the blood vessels that feed tumors. However, as time goes on, tumors become more resistant to chemotherapy and radiation, requiring larger and larger doses of toxic chemicals to fight tumors. This new direction allows for a more effective means of administering tumor fighting treatments without increasing chemotherapy and radiation dosages.
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