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NicVAX: experimental nicotine quit smoking vaccine

The University of Wisconsin Center for Tobacco Research and Intervention is conducting a study on NicVAX, an injectable nicotine vaccine, to determine how effective it might be in helping smoker's quit smoking cigarettes. In addition to the experimental vaccine, participants in the study will receive quit-smoking counseling.

"We are pleased to have been selected to test an experimental nicotine vaccine - a potentially important advance in treating tobacco addiction," says Michael Fiore, UW-CTRI director. "In this study, we will examine how the vaccine can help smokers break free of their dependence on tobacco - by reducing the effects of nicotine on the brain."

According to the researchers, every year 300,000 Wisconsin residents try to quit smoking and only one in 20 smokers who attempt to quit smoking cold turkey succeed. Because of the high-volume of volunteer interest, this study is closed to further participants. However, a second study by the Wisconsin Smokers' Health Study is still accepting new participants for an investigation into various stop-smoking treatments.

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