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The Lance Armstrong Effect: heat kills cancer cells theory

ABC News aired a health news story to discuss the Lance Armstrong Effect, named after the seven-time Tour de France champion who survived testicular cancer even after it had spread to his lungs and brain -- why so many testicular cancer patients survive cancer -- and how it might be heat that is killing testicular cancer cells.

Johns Hopkins University researchers hypothesis it might be simply a matter of heat. Testicles are naturally a few degrees cooler than the rest of the body, and when the temperature of testicles are raised to normal body temperature, testicular cancer cells appear to be destroyed.

Because Armstrong's testicular cancer had spread beyond his testicles, researchers began to consider that heat might have played a role. The focus on Armstrong led to the term the Lance Armstrong Effect when referring to cancer cells destroyed by heat. In all fairness, the oncologists point out, this could have been named after any testicular cancer survivor.

"We've known for a long time that heating cancer cells kills them," said Dr. Donald L. Trump, an oncologist and senior vice president of clinical research at Roswell Park Cancer Institute in Buffalo, N.Y. Hypothermia treatment has been used in kidney and liver cancer cases.

In the interview, Dr. Trump explained that a needle is inserted into the tumor and the temperature raised up to 120 degrees. For whole body hypothermia treatment, the temperature can only safely be raised to 102 to 106 degrees. To watch the news video and learn more about the Lance Armstrong Effect and the applications of heat in killing cancer cells, go here.
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