If you have been diagnosed with stage I, stage II or stage III breast cancer you might be eligible to participate in a trial that uses bisphosphonates as adjuvant therapy along with standard treatments.
When breast cancer metastasizes it often spreads first to the bone. Bisphosphonates have been shown to slow the progression of cancer in the bone. This trial will test to see if bisphosphonates when used as adjuvant therapy may delay or prevent bone metastasis from happening altogether.
This phase III trial will compare two newer and stronger bisphosphonates with a bisphosphonate called clodronate that has been shown to interrupt bone metastasis in early stage breast cancer.
Bone metastasis can lead to fractures, spinal cord compression and it can be very painful. If we can halt the spread of breast cancer to the bone with an additional adjuvant therapy it can save many lives.
