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Uncovering clues to brain cancer

Glioblastoma is the deadliest form of brain cancer, most often striking patients in their 50s and 60s who after diagnosis typically have only 10 to 12 months to live.

Glioblastoma is a shocking diagnosis -- and while the tumors don't tend to spread outside the brain, they resist surgery and return even when half the brain is removed. They also are resistant to most treatment. Clearly, insight into this deadly cancer is a must. Thankfully, a little slice of insight has just emerged.

Armed with findings from experiments in mice, researchers report they've discovered a clue that might help unravel the mystery of glioblastomas.

Studies show that some mice recovered from a human form of brain cancer when given bone morphogenetic proteins that appeared to interfere with the cancer growth process in stem-like cells. This leads researchers to believe the proteins could be used to stop cancer growth and prevent it from recurring.

The research is not ready for prime time, says one of the researchers who maintains there is still a long way to go. Yet the findings are promising -- and they suggest stem cells may play a critical role in tumor formation.

About 17,000 to 18,000 Americans develop brain cancer each year. Half of these patients will be diagnosed with glioblastoma.
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