The earlier a cancer is detected, the greater the chances for cancer survival. One of the problems in surviving colon cancer is that people are reluctant to undergo colonoscopies, and therefore, colon cancer is not always detected in its earliest stages before symptoms develop. Mount Sinai School of Medicine and EXACT Sciences Corporation are publishing study findings that show a DNA stool test can accurately predict colorectal cancer 88 percent of the time, regardless of where in the colon the cancer is located.
"This study confirms that stool-based DNA technologies can achieve high sensitivities for detecting colorectal cancer," stated Steven Itzkowitz, M.D., principal investigator and Professor and Associate Director of Gastroenterology at Mount Sinai School of Medicine. "For those individuals who are unwilling or unable to undergo colonoscopy, stool DNA testing offers a valuable and patient-friendly screening option. These results also underscore that as new markers and technologies are developed and validated, they can readily be incorporated into existing stool DNA tests to improve cancer detection and, ultimately, patient outcomes."
According to statistics, colorectal cancer is the second leading cause of cancer deaths in the U.S. and more than half of the over 80 million people over the age of 50 have never been screened. I agree with the researchers who suggest that it is time to develop new non-invasive technologies for colorectal screening.
1. Seems so obvious that the American Cancer Society should include DNA stool testing in their colorectal cancer guidelines. 88% sensitivity is far better than anything else out there except colonoscopy, which people tend not to want to do when asymptomatic given discomfort and fear of the procedure.
Posted at 10:22PM on Feb 11th 2007 by ddlewis