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Scientists know how melanoma spreads

Researchers at the Marie Curie Institute have said that they now understand how melanoma spreads to other parts of the body. They feel that this information can help in uncovering how other cancers metastasize.

A gene called MITF controls a switching mechanism inside the malignant cell. It seems that MITF levels determine whether the cell is dividing, proliferating, forming a tumor, or whether it goes into a non-dividing state, which becomes highly invasive. The researchers were surprised and assumed that the dividing cells would become invasive.

Chemotherapy goes after dividing cells so researchers think that these non-dividing cells are the dangerous ones that lead to metastasis to other organs.

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