Avastin, which is used for advanced colorectal cancer, has been linked to tracheo-esophageal fistulas in a small number of Canadian patients, according to Health Canada officials. Tracheo-esophageal fistulas are abnormal connections between the esophagus and the trachea."A direct cause and effect between Avastin and these events has not been established, but cannot be ruled out," Health Canada said in its advisory. "Avastin should no longer be given to patients who develop a TE fistula."
Health Canada officials recommend that patients taking Avastin should contact their physicians if they develop any of the following: chest pain, shortness of breath, wheezing or labored breathing, coughing or choking when eating or drinking, coughing up food or liquids, or wheezing sounds following every breath.
Although a direct cause and effect relationship has not been confirmed between Avastin and TE fistula, it is still something to be aware of if you or a loved one is using this treatment.
