Note: The contents of this blog are for informational purposes only and should not be construed as medical advice or substitute for professional care. For medical emergencies, dial 911!
According to a new Finnish study, most head-and-neck cancers that recur locally after prior full-dose conventional radiation therapy respond to Boron Neutron Capture Therapy (BNCT). This research was led by Heikki Joensuu at the Helsinki University Hospital. According to the researchers, this work opens up a new field of use for BNCT, which has been evaluated only for the treatment of brain tumors.
BNCT is a form of targeted radiation treatment and is considered experimental. A boron-containing compound is infused into a peripheral vein and accumulates in the cancer. The cancer is then irradiated with neutrons from a nuclear reactor, causing the boron to split as a result of neutron capture. This releases radiation which can then destroy cancer cells.
The Lori Arquilla Anderson Foundation for Brain Cancer is promoting awareness of the life threatening effects of brain tumors, advocating on the behalf of cancer patients and raising funds for medical research. LAAF is dedicated to making a difference towards finding a cure.
You can read more about Lori's diagnoses, treatments and cancer journey here. Sadly Lori passed away on July 4, 2005. She was diagnosed with Glioblastoma Multiforme, one of the most deadly brain cancers.
This organization keeps Lori's memory alive and reminds us also to -- live, love and laaf.
A recently-published study has found that a significant proportion of children under the age of three with the brain tumor ependymoma can skip or delay radiotherapy by using chemotherapy without lowering their chances of survival.
This research has taken 12 years to complete and were released in Lancet Oncology in July 2007 by the Children's Cancer and Leukaemia Group at The University of Nottingham in the UK
Radiotherapy can be harmful to a young child's brain, affecting IQ, short term memory, growth and puberty.
According to experts, the survival rate for children with ependymoma is increasing, but still unacceptably low.
Tomorrow I report for one of my six-month radiation follow-ups. My radiation oncologist will review how I've fared for the past two years since my left breast was zapped, day after day, week after week, in an aggressive attempt to keep cancer from returning to the same local area where it first reared its ugly head. How horrified I would be if I learned the machines used to treat my cancer were faulty, that they did not in fact do anything aggressive, that they were essentially ineffective.
Hundreds of brain cancer patients may be hearing this horrific news, now that malfunctioning machines have been ordered shut down following a manufacturer's warning.
Brainlab of Munich, Germany claims a small targeting error occurred with their machines but that it is unlikely to cause problems for patients. If I were one of these patients, I would still be worried. Targeting the tumor bed area is crucial in any cancer treatment. I don't like the sound of "targeting error," regardless of how minor it may be.
Endometriosis increases the risk of certain cancers according to a recent analysis by Dr Anna-Sofia Melin at the Karolinska University Hospital in Stockholm, Sweden. About 63,000 women who had been given a diagnosis of endometriosis between 1969 and 2002 were identified. In endometriosis, cells that usually only grow within the uterus grow outside the uterus.
The researchers found that endometriosis increased the risk of developing ovarian cancer by more than a third above the risk for women who did not have endometriosis (37%). There were similar increases in risk for endocrine tumours (38%), kidney cancer (36%) and thyroid cancer (33%). Slightly lower increases were found for brain tumours (27%) and malignant melanoma (23%), and there was a small increased risk of breast cancer (8%). In contrast, women with endometriosis had a reduced risk of cervical cancer of just under a third (29%).
However, there was no difference found between the risk of cancer in women with endometriosis who had borne children versus those who had not.
Dr. Melin cautions that it is too early to use the results of this study to give advice to doctors, but she stated, "Our hope is that doctors in general start to view the endometriosis disease as a serious disease that causes a lot of suffering to the patient and also may lead to cancer. We hope that in the future we will be able to identify those women with endometriosis that may have a more aggressive form of disease with more atypical cells, for instance, and that this may lead to better care for the patient and, hopefully, to a early diagnosis if cancer should occur."
Staff Sgt. Elizabeth Cowie's dream almost ended when she was diagnosed with breast cancer in May. She was told earlier in the year that she would deploy to Iraq this summer.
The forty-two year old mother is ready for duty after her aggressive treatment plan. She had two surgeries and a five day targeted radiation treatment called MammoSite. Elizabeth will leave later this month with the 1113th Transportation Company of San Jose, California, for at least a year transporting supplies in Iraq.
Elizabeth's mother Pearl said she "isn't surprised that her daughter still wants to deploy. I knew this would not deter her. She was just determined to go. That is the kind of person she is."
So many of the cancer patients I know end up becoming experts not only on cancer in general, but in the specific details of the kind of cancer that has invaded their respective bodies. Are there ways to valiantly fight many types of cancer? You bet there is.
If you or someone you know has been diagnosed with brain cancer, WebMD has published a very good short list of 10 popular questions your doctor or oncologist should be asked. As with any type of cancer, there are no simple questions or simple answers.The devil is in the details here, and becoming informed and showing informed concern for your own condition is mentally one of the healthiest things you can do.
Click here to see what the 10 best questions about brain cancer that can be asked to your physician. These will help prepare you for what is coming (or not coming) and will set you up psychologically for what lies ahead.
I found David's website while researching about Glioblastoma Multiforme (GBM), the most aggressive type of brain tumor. I found his website to be very inspiring. My uncle died of GBM twenty years ago this coming holiday season. David is an 11 year survivor this year! You can visit David's website at www.davidmbailey.com.
How did you find out you had cancer?
I started getting these really bad headaches. One morning, I fell over and felt nauseous. My wife called 911 and I remember getting in the ambulance thinking it was silly. I had a small seizure in the ambulance and when we got to the ER, I had a major grand-mal seizure. They did a quick cat-scan and saw a large mass in my head so they put me on a helicopter and flew me to a bigger hospital where they operated the next morning to remove the baseball size tumor in my brain. The pathology came back with the bad news -- grade 4 glioblasoma multiform (GBM) Prognosis, 6 months to live.
What types of cancer treatments were recommended?
I originally saw a general oncologist who had one clinical trial to offer but it was a randomized study, meaning a computer would pick if I got the treatment. I thought that was stupid. Then he gave me the best advice possible -- he told me to see a NEURO oncologist -- someone who specialized in heads.
Glioblastoma Multiforme (GBM), also known as a grade IV astrocytoma, is the most common and most aggressive type of primary brain tumor. Although GBM can occur at any age, the disease is most commonly diagnosed after the age of 50.
I wanted to discuss this type of cancer and add it to the Cancer by the Numbers feature because it has directly affected my family. My 39-year-old uncle died of the disease in 1987. He only survived a year after diagnosis. It is disheartening that this disease has not seen any strides in improved survival rates over all these years.
The Numbers
GBM accounts for 52 percent of all primary brain tumor cases. Brain tumors account for one in every 100 cancers diagnosed annually in the United States. Most malignant brain tumors and brain cancers have spread from other tumors in the body to the skull, including cancers of the breast and lung, malignant melanoma and blood cell cancers.
The Utah Jazz's Derek Fisher finds himself in a whole new ballgame lately as he helps his 10-month-old daughter, Tatum, fight for her life.
Tatum was diagnosed last week with retinoblastoma, a cancerous tumor in her left eye. Fisher, who was excused from his team to begin dealing with his daughter's illness, flew his family -- his wife Candace, Tatum, and Tatum's twin brother Drew -- to New York on Monday to see a specialist.
Fisher and his wife must decide on a course of treatment for their daughter. Their options are removal of the eye or a combination of surgery and chemotherapy. Their most pressing goal is to save Tatum's life. They also want to save her eye. And they think in her case, she should be able to keep her eye.
New hope may be an injection away for patients living with glioma, a terminal brain cancer that comes with a life expectancy of about 25 weeks post-diagnosis.
A new vaccine called Vitaspen is made by using tissue extracted from each person's cancerous tumor. The tissue is used as a unique footprint for the vaccine that targets destructive tumor tissue while sparing healthy tissue in the same region.
Vitaspen is only in the first stage of clinical human trials, but researchers are pleased with the promise of the new drug -- particularly the benefits trial participants are gaining form the treatment. They have reported no adverse side effects, and the drug has increased the overall survival rate.
Results of stage one trials will determine if the drug warrants stage two testing.
The Boston Marathon takes place today. And one runner -- known to friends and family as Running Bear -- will run to raise money for brain tumor research. She's already collected more than $3,500.
Harvard student Sarah MacCarthy, 25, will run for her Uncle Tim, who is battling glioblastoma (GBM), the most aggressive form of the primary brain tumors known collectively as gliomas.
If Uncle Tim can fight for his life, MacCarthy can use her privilege of good health to make a difference -- even if it means stepping up her casual running to marathon standards.
The Brain Tumor Society will benefit from MacCarthy's determination. Dedicated to improving quality of life for patients, survivors, and families affected by this disease, BTS is committed to being a national leader in the quest for a cure.
It seems MacCarthy is pretty committed herself. To contribute to her efforts and check on her progress, click here.
It didn't register right away. But not long after I finished doing some research yesterday on breast cancer screening tools did I realize the statistics on breast cancer incidence have changed for 2007. Not only did they change -- they're moving in exactly the right direction.
Think about this:
The American Cancer Society reports that 178,480 new cases of invasive breast cancer will be diagnosed in American women in 2007. This number was 212,920 in 2006. Deaths by breast cancer -- there were 40,970 in 2006 -- will number 40,910 this year.
Just as it had become second nature for me to rattle off 200,000 as the general number of women diagnosed with breast cancer each year, I must learn a new number. I love it.
OK, we all know young women get breast cancer. But the way some talk about the pair -- young women and the deadly disease -- it would seem finding a young one living with this type of cancer is like locating that needle in a haystack. Many a young woman -- like me -- have heard doctors and nurses and technicians and family and friends remark, "you are too young for the disease," and then dismiss cancer suspicions as needless worry.
The median age for women diagnosed with breast cancer is 65. But think about this fact, published in the Spring/Summer edition of Beyond: Live & Thrive After Breast Cancer.
More than 240,000 women in the United States age 40 and under are living with breast cancer. Each year in this country, more than 14,000 women 40 years old and younger are diagnosed with breast cancer, says Boston oncologist Ann Partridge, M.D., of the Dana-Farber Cancer Institute.
That's a lot of young women. That's a lot of breast cancer. And yet, mammograms still are not recommended for women under the age of 40.
A friend of a friend was diagnosed this week with a cancerous brain tumor -- a glioma to be exact -- and the surgery to remove the mass is scheduled for Monday.
I don't know much about this woman or her cancer, but I do know doctors told her yesterday she will likely survive for only a few years. I can't help but think that if doctors had given me this same prediction at the time of my cancer diagnosis, my time would just about be up.
I can't fully grasp the magnitude of this sad and sobering news. But I can comprehend that any one of us could be on the receiving end of such an announcement at any given moment. We are all vulnerable. And so I am confronted once again with the powerful and painful reminder that each day really could be my last.