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Posts with tag Alcoholics

First evidence of alcohol, cancer link emerges

When Dr. Jian-Wei Gu went to Mississippi to study the cardiovascular system and the process of blood vessel growth, he had no idea he'd make national headlines about his research into the world of cancer.

Gu, assistant professor of physiology and biophysics at the University of Mississippi Medical Center, says his discovery of the mechanism by which alcohol consumption causes tumor growth was purely accidental.

And extremely significant.

Scientists have known for a hundred years about the link between alcohol consumption and cancer. A study from Paris in 1910 showed that 80 percent of patients with cancer of the esophagus or gastric track were alcoholics. More recently, scientists have found correlations between alcohol consumption and cancer of the mouth, pharynx, larynx, esophagus, liver, large bowel, and even the breasts. Yet lab experiments have always failed to show the effects in animals that investigators knew to be true in humans.

Until now.

It seems past studies used too much alcohol -- in concentrations of 20 percent -- and the animals just wasted away while showing no tumor growth. But when Gu used concentrations of one percent -- about one to two drinks per day in humans -- to study blood vessel growth, he detected stimulated tumor growth in both chick embryos and mice. Thus, his cancer discovery was born.

Gu has further concluded that melanoma cancers in mice grew significantly faster and larger in the mice who consumed the equivalent of one or two alcoholic drinks a day than the mice receiving no alcohol.

Gu's findings, now confirmed by other scientists, are evidence of what many have long suspected -- alcohol, even in moderation, increases cancer risk.

Opiate blocker naltrexone shows success in treating women smokers

In a recent study, researchers found that the opiate blocking drug naltrexone, used to treat alcoholics and heroin addicts, was effective in helping some women kick the smoking habit. In addition, the researchers reported that naltrexone prevented the weight gain that often follows when women quit smoking.

Participants in the study were divided into two groups. One group was given a combination of drug therapy, behavioral counseling sessions, and nicotine patches. The other group was given a placebo, behavioral counseling sessions, and nicotine patches. For women receiving naltrexone, 58 percent were still not smoking eight weeks later. Six months later, some had taken up the smoking habit again, but some had remained free of the habit.

Naltrexone did not appear to provide a benefit for men trying to quit smoking.

"Women have historically had less success than men in giving up cigarettes," said study author Andrea King, PhD, associate professor of psychiatry at the University of Chicago. "In this small study, naltrexone seems to have closed that gap."

The study, Efficacy of Naltrexone in Women's Smoking Cessation, is currently ongoing and recruiting new patients.

Alcoholism and binge drinking threaten to shorten life

Recently, International Agency for Research on Cancer researchers concluded a study which stated that 3.6 percent of all cancer cases worldwide are related to alcohol drinking. Today, the Centre of Public Health at Liverpool John Moores University published a report that alcoholism and binge drinking in the northern Britain cities of Newcastle-upon-Tyne, Liverpool and Durham will shorten the lives of men and women who live there and create years of health-related illnesses.

The blame for the drinking problems focuses on the government's allowance of 24-hour drinking, inexpensive booze, a night-time economy of bars and clubs and a failure to educate the public on the dangers of excessive drinking, binge drinking and alcoholism. This report, along with political conservatives, are making a public statement against what they call irresponsible actions on the part of the British government that would create an environment that promotes excess drinking, binge drinking and alcoholism.

The report indicated almost three in ten people admit binge drinking. According to director of the Centre for Public Health Professor Mark Bellis, "We hope that making these statistics widely available will highlight that we are no longer a nation enjoying a harmless tipple but increasingly one developing a dangerous alcohol addiction."

A survivor's tale: AA principles used during chemotherapy

"It's said that chemotherapy is like skiing in front of an avalanche. You do one thing wrong, and the avalanche is going to get you." -- Harvey Rushfeldt

Using the principles he learned in Alcoholics Anonymous, AA, helped Harvey Rushfeldt, 72, diagnosed with non-Hodgkin's lymphoma last October, create a strategy for successfully living through the often grueling ordeal of chemotherapy. Rushfeldt sees both cancer and alcoholism as mortal threats and he approached his cancer treatments with the same 12 step attitude and perspectives alcoholics adopt on the one-day-at-a-time road to recovery.

Continue reading A survivor's tale: AA principles used during chemotherapy

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