On July 23, a milestone in presidential campaign history was delivered when Democratic presidential candidates fielded questions sent in via YouTube, a popular video sharing website where users can upload, view, and share video clips. On September 17, Republican candidates will take part in the second CNN-YouTube debate.

Aired live on CNN, this unusual debate featured 39 serious questions -- about immigration, climate change, the voting system, even cancer.

Thirty-six-year-old Kim of Long Island, who pulls off her wig mid-question, asks in her video clip about the millions of uninsured Americans who don't have access to preventative medical care.

Patrick Wayne, son of late actor John Wayne, says Larry King has true grit. And that's why the CNN talk show host will receive the True Grit Award next month, an honor that hails from the John Wayne Cancer Institute.

King, 73, will receive his honor at the annual Odyssey Ball on April 14 at the Beverly Hilton Hotel. Jamie Lee Curtis will host the event that will commemorate the centennial of John Wayne's birth.

The Odyssey Ball began 22 years ago and has helped raise more the $14 million to support the John Wayne Cancer Institute's research and treatment programs.

"Larry King epitomizes the strengths and qualities that characterized my father, and for which the True Grit Award was created," said Wayne, who serves as chairman of the board at the institute, located at the Saint John's Health Center in Santa Monica.

Founded by the Wayne family in 1981, the institute honors John Wayne who died of stomach cancer in 1979.

Elizabeth Edwards has been told the metastatic cancer found in her bones is considered stage four. And it's treatable. But not curable.

Tricky stuff -- all this cancer terminology -- and a little hard to fully comprehend.

I saw Sheryl Crow talking with Maria Shriver and Dr. Susan Love on Larry's King's CNN program the other night. Crow says her breast cancer was curable -- it was teeny tiny and had not spread and required a lumpectomy and radiation, but not chemotherapy. "I'm the walking poster child for early detection," she said. Her cancer was caught and treated swiftly. She is cured. Theoretically.

Can Crow's cancer still return? Yep.

We just aren't sure at the time of one cancer discovery if these deadly cells have drifted away from the main site and will later show up elsewhere, explained Dr. Love. All predictions would have Crow living a long life free of cancer. But they may have had Edwards in the same boat just two years ago when she was first diagnosed with breast cancer.

So now Edwards' cancer is not curable. It is treatable. And this is a bit easier to understand. Her cancer will never go away. But doctors can keep it at bay. And Love says they can even make it better. But there is no cure for what Edwards has. So she will live with cancer for the rest of her life.

I guess curable means: the cancer is gone and we hope it never comes back. And treatable means: the cancer is not gone and will never be gone but we will treat it for as long as we can.

I think I get it.

Angelina Jolie, who told CNN host Larry King on December 18 that her 56-year-old mother was battling ovarian cancer, is now confirming that her mother passed away on Saturday afternoon.

According to a new release, Angelina Jolie and brother James Haven were with their mom, actress Marcheline Bertrand, when she died this weekend at Cedars-Sinai Medical Center. It is reported that Jolie's boyfriend, Brad Pitt, was at the hospital with Jolie and her brother.

Bertrand, divorced from Jolie's Oscar-winning actor father Jon Voight and primary caretaker of her children, had small roles in the movies Lookin' to Get Out in 1982 and The Man Who Loved Women in 1983.

A private funeral is planned -- and the family asks that donations be made to the Women's Cancer Research Institute at Cedars-Sinai.

Lance Armstrong, champion of both cycling and cancer, wrote a commentary recently for CNN. His message was loud and clear -- he is losing patience with Washington politicians set on cutting funds for cancer research -- and while his words have not yet spurred positive change for cancer initiatives, they have inspired cancer survivors from all over the world who are responding with their own commentaries on sickness and survival.

The outpouring of sentiment inspired by Armstrong's commentary is overwhelming. Today, I offer just a glimpse into what survivors -- seven of them -- are expressing in the spirited e-mails they are sending to CNN.

Jerry Kelly of Birmingham, Alabama
My dad died of cancer 10 years ago, almost the same time Lance was diagnosed and subsequently founded the Lance Armstrong Foundation. My wife and I met Lance a few years later after I was diagnosed and we went to Austin for the LAF Ride for the Roses (fundraising bike ride). Lance's story had been very inspirational when I found it just minutes after my diagnosis with testicular cancer. What we didn't realize was how much inspiration we would get from other survivors and caregivers as we shared stories. Lance also spoke of something his doctor told him about, the Obligation of the Cured. The important thing to remember is that we can all make a difference if we are willing to give the effort. You don't have to win the Tour de France to join the LiveStrong Army!

Brian D. of Austin, Texas
The costs of this disease even for folks that have good insurance are well beyond reach. Depending on when you discover the cancer and what type of cancer you have, the out-of-pocket costs are far beyond the average person's ability to pay. This is of course assuming that you want to extend your quality of life and you want access to the latest advancements in cancer treatment. We are called society's "catastrophic cases." I am a 4½-year survivor of primary brain cancer. The technical name for my disease is anaplastic astrocytoma grade III. It is basically a slow-growing glioblastoma multiforme -- a death sentence. But I am young and up to the challenge. I am a card-carrying member of the LAF organization. I think what Lance is doing is great ... I think this article is great and I think our Congress should give more tax credits to those of us trying to live a normal life. Shame on them for not acting!

Anne Hawkins of Douglasville, Georgia
I was diagnosed with breast cancer at age 36. I am now 42½ and I have been diagnosed with breast cancer again -- a different type than the first time. I caught it in time thanks to my diligence in screening. However I am going through chemo for a second time in my life since it was an aggressive cancer and I'm so young. I am appalled that none of our politicians consider this a running topic! And the funding has been cut? That's unbelievable.

Marianna Costa, Melbourne, Australia
While I am writing from Australia, unfortunately the experiences of others sound all too familiar in our world. My wonderful father died in 2005 from cancer. The devastation to lives infested by cancer could never be measured in dollars. My conclusion is that cancer treatment is a global business. While I have faith in people of science to rid us from this world catastrophe, there is a global lack of resolve in governments, the corporate sector and medical institutions.

Casey Cronin of Austin, Texas
I'm 19 years old and I was diagnosed with cancer on December 3. I had my first surgery on December 7 and the second surgery on December 22. The pain I experienced was beyond belief. I had to accept the fact that I had cancer, go through with these surgeries, and sit in a hospital on Christmas. The second surgery was to remove my lymph nodes on my back and the nodes came back negative. Without cancer research I might not have been so lucky. I'm outraged that Congress has cut funding towards cancer research but continue to spend an arm and a leg on defense spending. I have a friend with Hodgkins lymphoma and unfortunately he doesn't have insurance. He's 23 and scraping by trying to make sure he might live past his 30s. Cancer is real threat to our health.

Betty Hoffmeister of Taylorville, Illinois
A year ago, October 2005, my daughter was diagnosed with stage 4 cancer of colon and liver. Not given much hope, but she is a fighter and a real sweet person. She takes chemo every other week on Monday, Tuesday and Wednesday, and then is so sick she has to stay in bed for a day or two. But then she gets up and does what ever her little body will let her do. They just say keep doing what you are doing, but we are really worried. I would like for her to hear some real encouraging news soon before she loses the will to keep fighting. God is very good. But we need help.

Scott Joy of Portsmouth, New Hampshire
I'm a 3½-year testicular cancer survivor, and an administrator for an Internet support forum for other survivors. As the Lance Armstrong Foundation sagely notes, "Cancer may leave your body, but it never leaves your life." Dealing with cancer is life-changing. I was blind to it before it hit me, but now I see cancer -- and its effect on individuals, families, and society -- every day. I am forever grateful for the LIVESTRONG movement, and the passion and power of the community of cancer survivors.

Angelina Jolie -- making even more headlines than usual as she speaks openly about falling in love with Brad Pitt -- has confirmed that her mother is battling ovarian cancer.

Jolie says in an upcoming interview with CNN host Larry King that her 56-year-old mom, Marcheline Bertrand, is doing good -- and she expects her to win her fight against the disease.

"She has fought for six years and she's a remarkable woman, she's very, very strong and her spirit remains unbroken."

Jolie's Larry King interview will air on Monday, December 18.

I read something yesterday written by a reporter who is fed up with the treatment of celebrities in the media. She is tired of the spectacular headlines about babies born to celebrities and adoptions by celebrities and every-day struggles of celebrities that blur the fact that these same things happen to real people -- non-celebrities -- and are rarely covered in the news. Sure, some of the celebrity coverage may lead to awareness. The fact that Angelina Jolie and Brad Pitt are talking of adopting another child may encourage others in the world to reach out to homeless children. But where is the news about hoards of women who gather and walk in search of a cure for breast cancer? And why was the coming-out announcement by former In Sync band member Lance Bass the top news story on CNN the other day? Because people pay attention to announcements like these -- and however disturbing it may be -- is causes a stir. And perhaps, like this reporter says, others will gain some strength from Bass and will tackle their own sexual orientation more openly.

A news story caught my attention the other night. Not because of the news -- initially -- but because of the names that were thrown around. Names like Kelly Ripa and Lindsey Lohan and Molly Shannon -- names that were not all that important in the scheme of the story I would eventually hear. But they hooked me. And then I learned about a great event that took place last Saturday in an effort to raise funds for ovarian cancer.

Super Saturday is a day-long summer fundraising event for the entire family -- created by Donna Karan and sponsored by In Style magazine. The day features a designer garage sale with more than 200 designers, a raffle, a carnival for kids, food and refreshments, and goodie bags. All proceeds -- from ticket sales and the garage sale and raffles -- go to the Ovarian Cancer Research Fund. Last year's event raised $2 million. And this year, the tally for the ninth annual event that took place in the Hamptons, is yet to be reported. What was reported is that the event was a success -- and celebrities were in attendance. And that made me pay attention.

CNN is hosting Ask Sheryl Crow, an online form that you use to submit your question directly to the singer, songwriter and breast cancer survivor. Crow was diagnosed with breast cancer earlier this spring, and went through cancer treatments immediately after the diagnosis.

As a breast cancer survivor, Crow wants to reach out to others who have questions in regard to cancer and being a cancer survivor.

On Monday, July 31, CNN will publish Crow's responses to the questions sent in online. She is also scheduled to appear on CNN's Larry King Live the same day.

Sheryl Crow is emerging as an active advocate for cancer survivorship. Recently, before she joined the Dave Matthews Band in a concert at Fenway Park, Crow made a surprise visit to Boston's Dana-Farber Cancer Institute to visit children with cancer at the Jimmy Fund Clinic.

In addition, Crow sat down for a two-part exclusive interview with ABC's Good Morning America Diane Sawyer, where she opened up about the breakup with Lance Armstrong, her breast cancer diagnosis and her life as a breast cancer survivor. Sheryl Crow is a cancer survivor who is giving back. If you have a question you would like Sheryl Crow to answer, just ask her.