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Posts with tag Colorectal
Posted Jun 30th 2007 3:30PM by Kristina Collins
Filed under: Chemotherapy, Colon and Rectal Cancer, Research, Surgery
There are several treatment options for liver metastasis, one being surgery. Results published in the Archives of Surgery state that repeat surgery to remove cancer that has spread to the liver provides significantly improved survival among patients with colorectal cancer.
The surgery, called hepatectomy, is the surgical removal of cancer and the surrounding tissue. Researchers recently evaluated data including treatment with repeat hepatectomies among patients with colorectal cancer and liver metastasis. The study included 64 patients who underwent one or more hepatectomies followed by chemotherapy.
At five years the overall survival was 53 percent. Among patients who experienced a cancer recurrence, five-year overall survival measured from the first hepatectomy was 73 percent among patients who underwent repeated hepatectomy, compared with 43 percent among patients without repeated surgery.
Posted Jun 21st 2007 9:10AM by Vicki Blankenship
Filed under: Colon and Rectal Cancer, Prevention, All Cancers, Research, Opinion, Diets, Nutrition, Cancer prevention foods, Recipe Healthy Living

Since the 1970s, researchers have suspected that diet and nutrition are related to colorectal cancer risk. Numerous studies published since that time have confirmed the connection between what we eat and risk of this cancer. Many health experts agree that a high fiber diet is important for cancer prevention, but questions remain about how much and which types of high fiber foods may reduce colorectal cancer risk most effectively. This has led to interest in specific high fiber foods, especially whole grains.
Start the day with a bowl of whole grain cereal or oatmeal. For cold cereals, choose one that contains at least 6 grams of fiber per serving and make sure you pick one where sugar does not appear first, second or third in the ingredient list. Oatmeal is not only high fiber but studies show that it helps reduce cholesterol. But if you are like me I am not fond of the mushy breakfast food. Until a dear musician friend introduced me to steel oats. Now I can't get enough of these nutty oats and even eat them for late night snacks.
Steel cut oats are whole grain groats which have been cut into only two or three pieces. Which means the the inner portion of the oat kernel is not missing like in rolled oats. They are golden in color and resemble small rice pieces. Steel-cut oats are also known as coarse cut oats, pinhead oats, Scotch oats, or Irish oats. Because the steel cut oats are more natural with less pre-processing, they may be more nutritious than the more popular rolled oats. But to me they give off a more nutty taste and I like the small crunch over the mushy consistency of the rolled oats. The cooking time is longer on steel cut oats but really worth the wait.
When shopping for them in your grocery store, look for canisters much like coffee cans as they are kept in air tight containers.
Preparing your Steel Oats.
1 cup steel cut oats
4 cups water
1/2 tsp salt
1 tsp butter
Fresh Blueberries or other fresh fruits.
Combine oats and other ingredients in medium saucepan and bring water to a boil over high heat, then reduce heat to medium. Simmer for 30 minutes stirring occasionally to keep from sticking on the bottom. For the last 5 to 10 minutes of cooking time you will need to stir more frequently as it thickens. Spoon into a bowl and top with fresh fruit. Some people like to add a little milk to the bowl to give them a creamy texture. Makes 4 servings.
Posted Jun 12th 2007 7:30PM by Kristina Collins
Filed under: Chemotherapy, Colon and Rectal Cancer, Clinical Trials, Research
At the 2007 meeting of the American Society of Clinical Oncology, results were presented from a clinical trial that stated -- Continuous maintenance therapy may improve survival among patients with metastatic colorectal cancer.
Maintenance therapy is used when a patient's cancer is stable and not exhibiting signs of progression. Researchers want to find a way to improve survival, but they also want to find a program that is not too intense and will have limited side effects.
This brings us to the study that was done on 202 patients with metastatic colorectal cancer. The patients were split in two groups, one group received continuous maintenance chemotherapy with a drug called Eloxatin (oxaliplatin). The second group was only treated again with chemotherapy once their cancer had started to progress.
Continue reading Metastatic colorectal cancer and maintenance therapy
Posted Jun 7th 2007 4:45PM by Kristina Collins
Filed under: Chemotherapy, Colon and Rectal Cancer, Clinical Trials, Research, Surgery
A late-breaking session at the 2007 annual meeting of the American Society of Clinical Oncology (ASCO) says that "Patients with colorectal cancer whose cancer has spread to the liver have improved survival without cancer recurrences when they receive chemotherapy prior to and following surgery, compared to those treated with surgery only."
Adjuvant chemotherapy is when chemo is used after surgery. Neoadjuvant treatment is when chemotherapy is given to shrink the tumor to allow for better surgical removal.
The second leading cause of cancer-related deaths in the United States is colorectal cancer. Liver metastasis is common among patients with advanced disease. A clinical trial was conducted to evaluate the use of chemotherapy before and after surgery compared to surgery alone. The trial included 364 patients who were divided into two treatment groups.
At nearly four years' followup, recurrence-free survival was 42.4 percent for patients receiving chemotherapy before and after surgery, compared with only 33.2 percent for those treated with surgery only.
Posted May 30th 2007 1:30PM by Kristina Collins
Filed under: Colon and Rectal Cancer, Diets, Cancer prevention foods
Even though there has been much hype in recent years about the connection between dietary fiber intake to decrease the risk of colorectal cancer, results of a large study does not support such a link.
The findings were reported in the May issue of the American Journal of Clinical Nutrition. The conclusion came after analyzing more that 291,000 men and 197,000 women ages 50 to 71 years. "Our study did not show any association between how much dietary fiber you eat and your risk of colorectal cancer" said the lead author of the study.
However, the lead author did say that he found consumption of whole grain foods may lower the risk of developing the disease.
Posted May 6th 2007 12:00PM by Kristina Collins
Filed under: Colon and Rectal Cancer, Television, Cancer Survivors
Living With Cancer is an inspirational documentary that will air on the Discovery channel tonight at 8pm EDT. Hosted by Ted Koppel, it chronicles the experiences of Leroy Sievers, an executive producer at Discovery.
In 2002 Sievers was diagnosed with colorectal cancer that had metastasized to his lungs and brain. The program features a discussion with Sievers as he deals with chemotherapy, scans and cutting edge procedures.
Koppel says the program is intended to show that people can and do live successfully with cancer everyday.
Sievers says "Normalcy is the greatest gift anyone can give you, let me continue to be me, not cancer. I am not my disease, I just have a disease. That's all"
Tune in -- I know I will.
Posted Mar 16th 2007 10:00AM by Jacki Donaldson
Filed under: Colon and Rectal Cancer, Prevention, Cancer events, Research, Politics

On February 5, the President cut about $11 billion from the National Cancer Institute budget. On March 20, one group -- the
Colorectal Cancer Coalition or C3 -- will ask Congress to return some of this money.
Colorectal cancer advocates from all over the country will descend upon Washington DC on this day, in honor of
National Colorectal Cancer Awareness Month. Their plan of action on behalf of C3's first-ever
Call-On Congress includes meeting with members of Congress face to face, discussing cancer research and prevention funding, and informing these powerful people that the time to cure cancer is now.
These advocates have a lot to accomplish -- and they need your help. So they ask that while they are rallying in DC that you lend your support with a few simple phone calls.
On Tuesday, March 20, between the hours of 9:00 AM and 5:00 PM Eastern Standard Time, pick up your phone and call two Senators and one Representative. Tell them now is the time for all good men and women to come to the aid of the cancer cause.
C3 offers a
step-by-step guide for making yourself heard. The group will help you locate your specific legislators and provides a script for what to say and how to say it.
"The more people who call on March 20th and ask for Congress to make funding the war on cancer a priority, the better for us all," says one advocate.
Posted Mar 11th 2007 10:00AM by Jacki Donaldson
Filed under: Colon and Rectal Cancer, Sunday Seven

A little bit of education goes a long way, especially in the war against cancer. Armed with facts and figures and know-how, we can help advance prevention and early detection of this deadly disease.
So in the spirit of National Colorectal Cancer Awareness Month, here are seven truths that serve to broaden your horizons about the third most common cancer found in men and women in this country.
As you read these truths, be aware that the death rate from colorectal cancer has been on a downward climb for the past 15 years due to better screening, fewer diagnosed cases, early detection, and more advanced treatment. Keep in mind that you can help keep this trend going by raising your own awareness and by taking action on behalf of yourself and your loved ones.
- Colorectal cancer refers to cancer that starts in the colon or rectum. These cancers begin in the digestive system where food is processed to create energy and rid the body of solid waste matter.
- Colorectal cancers develop slowly over a period of years and mostly begin in the form of polyps -- growths of tissue that start in the lining and grow into the center of the colon or rectum. Removing polyps early may prevent them from becoming cancerous. More than 95 percent of colon and rectal cancers are called adenocarcinomas.
- For people of average risk, screening is recommended beginning at age 50. Those whose risk is higher than average should talk with a physician about appropriate screening.
- Screening is used to detect disease in people who do not have any symptoms. In many cases, screening tests find colorectal cancers at an early stage and greatly improve the chances of successful treatment. Screening tests can prevent some cancers by allowing doctors to find and remove polyps that might become cancer. There are several tests used to look for colorectal cancer. Ask your doctor what test is best for you.
- Treatment for colorectal cancer includes surgery, radiation therapy, chemotherapy, and newer targeted therapies.
- The American Cancer Society predicts there will be 112,340 new cases of colon cancer and 41,420 new cases of rectal cancer in 2007 in the United States. Combined, the diseases will cause about 52,180 deaths.
- The Colorectal Cancer Coalition -- or C3 -- is a national organization whose mission is to eliminate suffering and death due to colon and rectal cancer through advocacy. Visit here for more information.
The material shared in this post was gathered from the websites of the
American Cancer Society and the
Colorectal Cancer Coalition.
Posted Mar 4th 2007 10:00AM by Jacki Donaldson
Filed under: Colon and Rectal Cancer, Events, Daily news

The Colorectal Cancer Coalition will visit the New York Stock Exchange tomorrow -- Monday, March 5, 2007 -- and will ring in the start of the business day.
Executive director Carlea Bauman will ring the NYSE Opening Bell in honor of Colorectal Cancer Awareness Month, and you don't have to be in New York to witness the wonder of it all. Just click
here and follow instructions for viewing a live webcast of The Opening Bell. It all begins at 9:25 AM Eastern Standard Time. You can also tune it to CNBC for coverage of the event.
The
Colorectal Cancer Coalition, also known as C3 and headquartered in Washington DC,
pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.
Posted Mar 1st 2007 9:00AM by Jacki Donaldson
Filed under: Colon and Rectal Cancer, Prevention, Events, Daily news

It's March. And that means it's the national month for Brain Injury Awareness, Endometriosis Awareness, Nutrition Awareness, Eye Health and Safety Awareness, Multiple Sclerosis Awareness, Sleep Awareness, Problem Gambling Awareness and my favorite, for the purposes of
The Cancer Blog -- Colorectal Cancer Awareness.
Colorectal cancer -- cancer of the colon or rectum -- is a disease that affects both men and women and is preventable nearly 90 percent of the time.
Starting at age 50, men at women at average risk for the disease should get screened. Those with increased risk, like African-Americans who typically develop colorectal cancer at younger ages, should be screened even earlier.
Screening -- by way of fecal occult blood test (FOBT), flexible sigmoidoscopy, and colonoscopy -- is critical because colorectal cancer often occurs with no symptoms. Symptoms do sometimes present themselves in the later stages of the disease and include rectal bleeding, bright red blood in or on the stool, change in bowel habits, stools that are narrower than usual, general stomach discomfort, diarrhea, constipation, frequent gas pains, unexplained weight loss, constant fatigue, and vomiting. Persistence of any of these symptoms for more than two weeks warrant an immediate visit with a health professional.
Treatment for this disease, which strikes about 153,000 people and causes about 52,000 deaths each year, includes surgery, radiation, and chemotherapy.
In the spirit of this National Colorectal Awareness Month, experts recommend remembering these important points:
- Colorectal cancer can be prevented.
- Screening for the disease can identify polyps -- grape-sized growths in the colon and/or rectum -- that can be removed to prevent cancer from developing.
- The magic age for screening is 50 -- unless you have an increased risk for the disease.
- Colorectal cancer is treatable.
- Regardless of your age, know the risk factors, know the symptoms, and know your family history.
- Talk with your health professional about colorectal cancer and your own risk for the disease.
Posted Feb 27th 2007 9:00AM by Jacki Donaldson
Filed under: Colon and Rectal Cancer, Research, Daily news

One in 18 men and women will be diagnosed with colorectal cancer during their lifetimes -- that translates into more than 150,000 people diagnosed and more than 52,000 colorectal cancer deaths each year, securing the disease as the second leading cause of cancer death in the United States.
Fortunately, mortality rates for this disease have been declining due to earlier screenings, awareness of symptoms, removal of polyps, and improved treatments through advances in research discoveries -- like today's genetic breakthroughs.
In a recent study, researchers identified a cell pathway critical in the development of colon cancer and also lung and stomach cancers.
STAT3 (signal transducer and activator of transcription 3) is the newest discovery and is a target regulated by PRPRT (receptor protein tyrosine phosphatase T), already identified to be mutated in these cancers.
"The role of protein tyrosine phosphatase in cancer is still an under-explored area," says Zhenghe John Wang, Ph.D., Assistant Professor, Department of Genetics at Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center.
"Our study shows that receptor protein tyrosine phosphatase T regulates an important signaling pathway that is critical in cancer development. This identification will allow new approaches to pharmacological designs and facilitate alternative approaches for cancer treatment."
This study, published in the
Proceedings of the National Academy of Sciences (PNAS Online Edition Feb. 20-23, 2007), provides new hope for the development of drugs that will target this potentially deadly disease.
Posted Feb 24th 2007 6:19PM by Vicki Blankenship
Filed under: Colon and Rectal Cancer, Prevention, Daily news

Colorectal cancer screening prevents more deaths due to early detection than breast or prostate cancer screening. The University of Michigan Comprehensive Cancer Center recently published a report on the
12 myths about colon cancer and getting to know them could save your life and the lives of your family and friends. Colon cancer is the second leading cause of cancer death in the United States, and the number one cause of cancer death among non-smokers.
Symptoms of colon cancer can include severe abdominal pain, blood in the stool or rectal bleeding, unexplained loss of weight, or major changes in bowel habits (recurrent constipation or diarrhea). But, these symptoms often do not occur until the cancer is in its more advanced stages. An absence of symptoms does not mean an absence of cancer. In fact colon cancer is often referred to as a "silent killer" because of the lack of symptoms until it is in advanced stages. A colonoscopy is the only method that can actually help prevent you from developing colon cancer in the future because during the screening colonoscopy, if the doctor finds polyps, they can remove them from your colon as part of the procedure, preventing the polyps from ever having the chance to develop into cancer. If the polyps found in your colon happen to already be cancerous, they can often be removed during your colonoscopy and treatment can begin right away.
When colon cancer is caught early, it has a 95 percent survival rate. That's why screening is so important. Once colon cancer has spread to the liver, it's usually deadly, with only a 9 percent survival rate. Colonoscopy screening is recommended for men and women beginning at age 50, unless other risk factors exist such as family history, obesity, smoking, ulcerative colitis or Crohn's disease.
Posted Feb 16th 2007 10:00AM by Jacki Donaldson
Filed under: Brain Cancer, Breast Cancer, Prostate Cancer, Ovarian Cancer, Colon and Rectal Cancer, Research, Daily news

Scientists have uncovered a gene they say may be cancer's master switch.
Like a circuit breast of sorts, the newly identified gene, CHD5, has an important job -- it's a tumor suppressor that prevents cancer from developing. But when it slacks on its job, cells begin to misbehave and tumors can form.
One professor of genetics says the gene, located on chromosome 1, governs the activity of a wide array of other genes involved in tumor-suppression. Its reach is large. And the implications of improper functioning are significant.
Cancers associated with the malfunctioning gene include brain tumors such as gliomas and breast, ovarian, prostate, and colorectal cancers.
A lot of people have been looking for this gene for decades. And now that it's been located, it will influence cancer research for years to come. The discovery will provide valuable new insight into targeted drugs and diagnostics and will turn up patients who need more aggressive treatment.
"We are really excited about our discovery," says the lead investigator of the research, which is published in the journal
Nature.
Posted Jan 27th 2007 10:00AM by Jacki Donaldson
Filed under: Drug, Pancreatic Cancer, Clinical Trials, Research, Daily news

One week ago, researchers found themselves humbled by the disappointing fact that promising cancer drug Avastin had failed to help patients with pancreatic cancer live longer. In fact, not only did the drug fail to extend survival, it actually caused adverse side effects such high blood pressure and bleeding in the stomach and intestine.
In a study of 600 patients with advanced pancreatic cancer, those who received Avastin in addition to standard chemotherapy lived for only six months -- the same amount of time as those who received chemotherapy alone.
Earlier studies predicted Avastin might improve survival. It worked in patients with advanced colorectal cancer. And so it was no surprise that crowds of pancreatic cancer patients wanted a shot at this potential wonder drug that in the end turned out -- for them -- to be not so wondrous.
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