Researchers at the Dana-Farber Cancer Institute in Boston say exercise helps combat breast cancer. Not the first time we've heard this fact. But these same researchers have something new to say -- about the reason physical activity lowers the risk of breast cancer recurrence.

Jennifer Ligibel, MD, of Dana-Farber, reports that exercise lowers levels of the hormone insulin in the bloodstream. This is significant because there appears to be an association between relatively high levels of insulin, seen in obese and sedentary people, and an increased risk of breast cancer recurrence and breast cancer-related death.

"We know that women who are overweight at the time of breast cancer diagnosis have a higher risk of recurrence than lean women, but the reasons for this have not been clear," said Ligibel.

OK, we all know young women get breast cancer. But the way some talk about the pair -- young women and the deadly disease -- it would seem finding a young one living with this type of cancer is like locating that needle in a haystack. Many a young woman -- like me -- have heard doctors and nurses and technicians and family and friends remark, "you are too young for the disease," and then dismiss cancer suspicions as needless worry.

The median age for women diagnosed with breast cancer is 65. But think about this fact, published in the Spring/Summer edition of Beyond: Live & Thrive After Breast Cancer.

More than 240,000 women in the United States age 40 and under are living with breast cancer. Each year in this country, more than 14,000 women 40 years old and younger are diagnosed with breast cancer, says Boston oncologist Ann Partridge, M.D., of the Dana-Farber Cancer Institute.

That's a lot of young women. That's a lot of breast cancer. And yet, mammograms still are not recommended for women under the age of 40.

It's been one year since Dana Reeve, wife of the late Christopher Reeve, died of lung cancer at the age of 44. And the grace of this woman, who came to represent the non-smoking population of lung cancer victims, is being honored by the Lung Cancer Alliance.

"Lung Cancer Alliance extends its most heartfelt thoughts to the family
and friends of Dana Reeve," says Laurie Fenton, president of the alliance.

"Dana's beauty, grace and valiant struggle against lung cancer will remain indelibly etched in our hearts and minds. In her memory -- and in the memory of loved ones lost to this disease, smoker or not -- let us come together to replace decades of stigma and neglect with hope, greater compassion and support for those living with or at risk for this disease. It is the right thing to do."

The Lung Cancer Alliance is the only national non-profit organization dedicated to patient support and advocacy for those living with lung cancer, the number one cancer killer.

Lung cancer takes more lives -- about 160,000 Americans this year -- than breast, prostate, colon, liver, kidney cancers and melanoma combined.

I know just how Jon Lester feels as he survives the cancer that took him out of the game of baseball and threw him into the arms of the medical system.

It's not the baseball I can identify with. It's the little bit of cancer fear that never really goes away. And it's the will to return to the land of the living that Lester and I share.

"When you're laying in bed at night, when you're not doing anything, you think about it a little bit," he says. "As long as I keep busy, I'm all right. Every now and again I feel something and go, `OK, what was that?' but I try not to think about it too much."

Lately, Lester is thinking mostly about a return to Boston's pitching staff, less than six months after a cancer curve ball came right at him, threatening both his promising career and his life.

Lester, whose weight was down to 190 during chemotherapy, is back up to 212 -- five pounds less than his normal weight -- and his arms are powerful, his legs strong, his appearance healthy.

As a rookie last year, Lester became the first Red Sox left-hander to win his first five decisions. He was 7-2 with a 4.76 ERA when cancer came crashing into his world. Diagnosed with anaplastic large cell lymphoma in August, Lester received treatment at both the Dana Farber Cancer Institute in Boston and at his hometown Hutchinson Cancer Research Center in Seattle. His last chemotherapy dose was delivered on December 4. His last check-up was in January. And now, newly 23 and cancer-free, Lester is ready to play ball.

Lester is prepared for his coaching staff to hold him back. He says he can tell everyone until he's blue in the face that he's ready but he knows the staff has his best interests in mind. He trusts their professional opinions, and he'll accept a return to the minors if that's what is in store for him.

"I'm not as hard on myself as I was last year," he said. "It's just a matter of enjoying playing baseball and not necessarily the result. So (I'm) just trying to enjoy things and take it day by day and live my life the best I can."

Peter Augustini's wife Jodi is fighting Stage IV breast cancer. They have three children, Charles, 10, Caroline, 7 and Max, 2.

Augustini is organizing a fundraiser to benefit the research Dana Farber Cancer Institute is using to help his wife fight breast cancer. He wanted to help Jodi and others fighting her type of aggressive breast cancer, referred to as Her-2 positive breast cancer.

Augustini decided to take on a holiday, Valentines day, that some people seem to think is a commercially contrived holiday. Augustini says "This is the chance to do something meaningful".

You can purchase a three inch wooden heart for your Valentine via the Share your Heart Fundraiser. The proceeds will benefit a fund specifically set up to fund research into a cure for Her-2 neu form of breast cancer. The research involves work on a drug called herceptin, which is attracted to specific proteins found only in cancer cells in the body.

The hearts are $5 each. You can also purchase a package of 10 for $20 and a package of 25 for $40. The hearts come unpainted and ready to decorate.

Share Your Heart Valentines are available for order vial the Dale, Wheelock and Memorial School Web sites, www.medfield.net or by e-mail to paugustini@cera.com.

Dr. Len Lichtenfeld, MD, is the deputy chief medical officer for the American Cancer Society. He is also a blogger and authors his very own blog -- called Dr. Len's Cancer Blog.

Dr. Len writes on his blog about all sorts of topics related to cancer. He shares his opinion on the recent drop in breast cancer cases (December 15, 2006), he promotes the Great American Smokeout (November 14, 2006), he sounds off on lung cancer screenings (October 25, 2006), and he urges parents to always slather sunscreen on their children (October 5, 2006). He has so much more to say -- and his blog is a great stop for those wishing for more information on hot cancer topics.

As this year comes to a close, Dr. Len offers a review of what he believes were the hottest cancer topics of 2006.

Dr. Len reflects in his blog about decreased cancer death rates that represent real progress in the fight against cancer. He calls the HPV vaccine a breakthrough and he recaps the STAR trial -- a comparison of raloxifene to tamoxifen to reduce the risk of recurrent breast cancer in post-menopausal women -- with emphasis on how raloxifene proved just as effective as tamoxifen, but with a better safety profile. He calls new targeted therapies a dream -- with a hefty price tag -- sure to garner debate and discussion in 2007.

Dr. Len reviews the Surgeon General's report on second-hand smoke -- it's harmful to non-smokers, the report says -- and he marvels at the capability of science to approach an understanding of what makes a cancer cell a cancer cell. He also remarks on how remarkable it is that chronic myelogenous leukemia is in fact chronic and no longer fatal, thanks to the drug Gleevec.

Of course, there is ample attention given to the declining incidence of breast cancer, reportedly due to less women using hormone replacement therapy, and the risks weighing on those who are overweight and obese, and survivors and supporters who gathered for Celebration on the Hill -- the site of one incredible American Cancer Society event.

Dr. Len closes his review of 2006 with recognition of three celebrities who lost their lives this year to cancer -- Dana Reeve, Ann Richards, and Ed Bradley. And while he recognizes there are other lives and other stories that deserve mention, there is simply not enough time or space for him to do justice to every noteworthy item.

"What we have seen over the past year is an incredible leap forward in cancer research, diagnosis and treatment, and I suspect there are going to be even more exciting developments in the coming year," says Dr. Len who looks forward to 2007 -- a year that is sure to deliver more hope and more progress in the fight against cancer.

In 2006, 174,470 people will be diagnosed with lung cancer in the United States. About 92,700 men and 81,770 women will develop the disease -- the leading cause of cancer death among both men and women.

An estimated 162,460 men and women will die of lung cancer this year, accounting for 28 percent of all cancer deaths and taking more lives than colon, breast, and prostate cancers combined. While most people diagnosed with lung cancer will die within the first two years of diagnosis -- this has not changed in 10 years -- some people are cured. There are currently about 333,000 long-term survivors.

Celebrities catch our attention. They cause us to pay attention too -- which is likely why the media uses celebrities and prominent people to send messages about all sorts of issues, like breast cancer.

It's not just the real-life survivor celebrity stories -- about Melissa Etheridge and Elizabeth Edwards and Sheryl Crow -- that make headlines and attract ratings. It's also the portrayal of cancer survivors on television that raises awareness about this disease. It's not a new trend -- it started long ago when All in the Family's Edith Bunker (Jean Stapleton) experienced a breast cancer scare, marking one of the first times the issue of breast cancer was discussed openly on TV.

Tough cop Mary Beth Lacey (Tyne Daly) of the TV show Cagney & Lacey traveled a breast cancer journey. Sisters eldest sister Alex (Swoosie Kurtz) was diagnosed with breast cancer and survived chemotherapy with family by her side. Beverly Hills, 90210 character Brenda Walsh (Shannen Doherty) found a lump in her breast and shed light on the fact that young women are not immune to breast cancer. Sex and the City's Samantha Jones (Kim Cattrall) developed breast cancer and proudly pulled off her wig on television. The L Word's Dana Fairbanks (Erin Daniels) lost her battle with breast cancer. And on Angela's Eyes, FBI agent Angela Henson recently learned her mother once had breast cancer -- and that it has come back.

There are many others television story lines woven with the thread of breast cancer. They draw viewers and boost ratings. They also raise awareness -- because people pay attention to celebrities.

The Jimmy Fund upped it's total by $2.8 million this Saturday -- thanks to celebrities Donald Trump, Ben Affleck, Billy Ray Cyrus, Jon Cryer, and others who helped raise funds for this cancer-fighting charity through a Boston radio-telethon. Established in 1948 to support cancer research at the Dana-Farber Cancer Institute, The Jimmy Fund has been the primary charity for the Boston Red Sox since 1953 and has been the beneficiary of this same radio-telethon for five years now. Since 2002, the telethon has raised more than $5 million to support research and care for both children and adults. This year's goal was to raise $2.6 million. With generous donations, the goal was reached -- and exceeded.

Trump -- who threw out the first pitch at the Red Sox-Yankees doubleheader on Saturday -- donated $60,000 to the charity. His donation jumped this year's total ahead of last year's $2.3 million. Red Sox owner John Henry donated $30,000, and Yankees owner George Steinbrenner gave $10,000. Massachusetts Senators Edward Kennedy and John Kerry also sent in donations during the 18-hour fundraiser that aims to strike out cancer.

In the second part of the two-part exclusive interview with ABC's Good Morning America Diane Sawyer, Sheryl Crow shares she is cancer-free and feeling great as a breast cancer survivor. The diagnosis of breast cancer came as a surprise as she is not a smoker and has no family history of the disease. She received enormous support from her family and friends during treatment, whom she refers to as "this incredible tribe of women." Before Dana Reeve died of lung cancer, she gave Crow advice on dealing with the emotional aspects of being a newly-diagnosed cancer patient and dealing with the recent separation from Lance Armstrong by telling her that the only way to go through grief was to grieve.

Crow talked about meditating and changing her diet. "I kind of went into a full-on Eskimo diet, where I ate a lot of salmon. In fact, I'm salmoned out of my brains ... and really green vegetables, just eating really clean, organic food. Listen, I haven't had a doughnut in I can't remember when."

Breast cancer forced Crow into an introspective place of self-realization in facing and overcoming fears -- and the wisdom that comes with that when she said she tried to at least address her fears and not be overcome by them. "The fear of things not always working out. You come to a point in your life where you realize it's not my job to prove to my parents or to my record label or to the world or to my lover that I matter. The fact is that you matter."

"It's not a good place to be concerned with always being right with everybody, always pleasing people, because ultimately you wind up betraying yourself a lot."

Crow shared that she sees her breast cancer diagnosis and being a cancer survivor as part of life's deepening experiences where obstacles are removed and opportunities come in.

Last Friday night, Crow joined the Dave Matthews Band in a concert at Fenway Park. But before she went onstage -- in part of giving back as a cancer survivor --  she made an unannounced surprise visit to Boston's Dana-Farber Cancer Institute to visit children with cancer at the Jimmy Fund Clinic.