I found David's website while researching about Glioblastoma Multiforme (GBM), the most aggressive type of brain tumor. I found his website to be very inspiring. My uncle died of GBM twenty years ago this coming holiday season. David is an 11 year survivor this year! You can visit David's website at www.davidmbailey.com.

How did you find out you had cancer?

I started getting these really bad headaches. One morning, I fell over and felt nauseous. My wife called 911 and I remember getting in the ambulance thinking it was silly. I had a small seizure in the ambulance and when we got to the ER, I had a major grand-mal seizure. They did a quick cat-scan and saw a large mass in my head so they put me on a helicopter and flew me to a bigger hospital where they operated the next morning to remove the baseball size tumor in my brain. The pathology came back with the bad news -- grade 4 glioblasoma multiform (GBM) Prognosis, 6 months to live.

What types of cancer treatments were recommended?

I originally saw a general oncologist who had one clinical trial to offer but it was a randomized study, meaning a computer would pick if I got the treatment. I thought that was stupid. Then he gave me the best advice possible -- he told me to see a NEURO oncologist -- someone who specialized in heads.

Glioblastoma Multiforme (GBM), also known as a grade IV astrocytoma, is the most common and most aggressive type of primary brain tumor. Although GBM can occur at any age, the disease is most commonly diagnosed after the age of 50.

I wanted to discuss this type of cancer and add it to the Cancer by the Numbers feature because it has directly affected my family. My 39-year-old uncle died of the disease in 1987. He only survived a year after diagnosis. It is disheartening that this disease has not seen any strides in improved survival rates over all these years.

The Numbers

GBM accounts for 52 percent of all primary brain tumor cases. Brain tumors account for one in every 100 cancers diagnosed annually in the United States. Most malignant brain tumors and brain cancers have spread from other tumors in the body to the skull, including cancers of the breast and lung, malignant melanoma and blood cell cancers.

The Boston Marathon takes place today. And one runner -- known to friends and family as Running Bear -- will run to raise money for brain tumor research. She's already collected more than $3,500.

Harvard student Sarah MacCarthy, 25, will run for her Uncle Tim, who is battling glioblastoma (GBM), the most aggressive form of the primary brain tumors known collectively as gliomas.

If Uncle Tim can fight for his life, MacCarthy can use her privilege of good health to make a difference -- even if it means stepping up her casual running to marathon standards.

The Brain Tumor Society will benefit from MacCarthy's determination. Dedicated to improving quality of life for patients, survivors, and families affected by this disease, BTS is committed to being a national leader in the quest for a cure.

It seems MacCarthy is pretty committed herself. To contribute to her efforts and check on her progress, click here.

Glioblastoma multiform, (GBM) is the most aggressive form of the primary brain tumors known as gliomas. The tumors do not spread throughout the body like other forms of cancer, but cause symptoms by invading the brain.

A new drug called AZD2171 (Recentin), is an angiogenesis inhibitor that blocks tumor blood supply and shows promise in treating deadly glioblastoma brain cancers. Recentin suppresses the growth of blood vessels that feed the tumors.

The preliminary findings of the Phase II study show that researchers found that Recentin could significantly reduce the size of glioblastoma tumors and can help reduce brain swelling.

"Patients with recurrent glioblastomas desperately need new, effective treatment alternatives," said study author Dr. Tracy Batchelor, chief of neuro-oncology.

Recent preliminary results from a Phase II clinical trial showed patients with recurrent glioblastoma multiforme, a form of primary brain cancer, experienced a significant tumor response rate with minimal side effects when treated with enzastaurin, an oral, targeted agent under development at Eli Lilly and Company.

On Thursday Eli Lilly & Co announced that it has stopped the Phase III trial of this experimental brain cancer drug. They determined that the treatment would not be any more effective than current chemotherapy treatments. The company said that it will still be evaluating enzastaurin as a potential treatment for non-Hodgkin's lymphoma. They will also be doing some trials that test the drug on other cancers, such as breast, colon, lung, ovarian and prostate.

Enzastaurin belongs to the families of drugs called protein kinase inhibitors and angiogenesis inhibitors.

The Mayo Clinic Cancer Center has opened a new clinical study today using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme (GBM). The Mayo Clinic's research has grown from the most basic laboratory science to the sophisticated therapy being tested today on several tumor types, including GBM, recurrent ovarian cancer and multiple myeloma.

The study is designed to test the safety of the virus for the treatment of gliomas and enable monitoring of anti-tumor activity. Eligible candidates for the therapy will have GBM that has progressed after surgery and radiation therapy. They also must be immune to measles, either having had the disease or been vaccinated against it.

Many cancer cells, including glioblastoma cells, overexpress a specific protein which allows tumor cells to avoid destruction by the immune system. Strains of the measles virus seek out this protein and enter the tumor. When it enters the virus begins to spread infecting nearby tumor cells which increases cancer cell death.

Back in the1970's it was noted that measles infections could cause regression of cancer tumors in children. Nothing was done about studying this phenomenon until late in the 1990's when the Mayo Clinic Cancer Center's Molecular Medicine Program began looking into it. The researchers are now also looking at ways to use the measles virus to combat breast and pancreatic cancer, they already have plans to open up another clinic study this fall to test the effectiveness of a version of the measles virus on multiple myeloma.