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Posts with tag RESTORE

First whole-ovary transplants now on the map

The first documented whole-ovary transplants are now on the map -- the United States map.

On February 5, a renowned infertility expert in St. Louis transplanted a whole ovary from one woman into her sister in order to enable the sibling to have children after a battle with ovarian cancer that resulted in early and permanent menopause.

Dr. Sherman Silber, who performed the same type of transplant on twins last month and has previously restored fertility via ovary tissue transplants, believes his success is unmatched. Apparently, surgeons in China have reported similar success but offer few details to support their claim. And due to a lack of published material about the case, it is believed Dr. Silber's ovary transplants may be the world's first scientifically documented cases.

Silber says whole-ovary transplants, that could potentially allow women with cancer to freeze an ovary, undergo treatment, and then have the ovary returned to restore fertility, could also one day help women who don't have cancer but experience natural premature ovarian failure, which leads to early menopause.

While both of Silber's ovary transplant patients are awaiting news about their status of their fertility, Silber awaits the long-term results of his work. Ovarian tissue transplants last a few years, but whole ovary transplants should last for decades, he says.

Common chemo aid causes bone loss, tumor growth

A drug commonly used to minimize the toxic effects of chemotherapy has been shown in mice to cause bone loss and promote tumor growth, according to the results of a recent study.

This drug, granulocyte colony-stimulating factor (G-CSF) -- also known as Neupogen, Neulasta, and Granocyte -- helps restore white blood cell counts that take a beating during chemotherapy, protecting cancer patients from an increased risk of infection.

According to researchers, G-CSF -- essentially a growth factor -- encourages bone breakdown. And any therapy that decreases bone density can enhance tumor growth in bones. So doctors are urged to closely monitor their patients during chemotherapy with regular bone density scans. They can also prescribe medications to prevent bone loss if necessary. And patients can protect their bones by consuming enough calcium and vitamin D and engaging in regular exercise.

Currently, research on cancer patients treated with G-CSF have not yielded the same strong results researchers found among mice.

The details of this study appear online in the journal Blood, and will be published in an upcoming print issue.

New book for survivors to heal faster, better and stronger

After Cancer Treatment is a Johns Hopkins press health book written by Julie K. Silver, M.D. Julie is a physiatrist, a medical professional in the field of rehabilitation, she is also a breast cancer survivor. Julie works as a medical director of Spaulding Rehabilitation Hospital's outpatient center in Massachusetts. She directs a program called RESTORE that helps cancer patients heal physically.

After Cancer Treatment includes ways to cope with common issues of survivorship, gives tips on exercise, a healthy diet and proper rest. Julie takes a look alternative therapies along with conventional medicine. Julie wanted to share her plan, one that worked for her and one she feels can help others coping with the road ahead after cancer.

Julie quotes philosopher Joseph Campbell "We must be willing to give up the life we planned, so as to have the life that is waiting for us."

Paul Newman plans another Hole in the Wall camp

A ninth Hole in the Wall camp is in the works -- thanks to actor Paul Newman who started the first camp for critically-ill children in Connecticut in 1988. Hole in the Wall camps host thousands of children for free and are now scattered all over the map -- in California, New York, France, and other locations. And one will soon open in Israel.

Each Hole in the Wall camp is a separate entity with its own distinct personality and name -- like The Victory Junction Gang in Randleman, NC and Camp Boggy Creek in Eustis, Florida. All camps share a common goal of building self-esteem and restoring joy in the lives of seriously-ill kids. And typical camp activities -- for kids whose diagnoses range from cancer to muscular dystrophy -- include rope climbing, face painting, horseback riding, swimming, and sports. It's a typical camp where children can enjoy childhood, without compromising their medical needs, due to state-of-the-art medical care.

Newman makes periodic visits to the camps and only partially funds the camps that mostly survive on their own through charitable contributions. He clearly loves the camps that have served more than 100,000 kids from 34 states and 31 countries and says he wants the camps to be the legacy he one day is remembered for. And what a legacy it will be.

Sunday Seven: Seven benefits of strength training

I have tried to exercise most of my adult life -- at times because I felt obligated to participate in what I knew was good for me and at times to justify eating my favorite foods while maintaining an appropriate weight and at times because I wanted to actually have a toned, healthy body.

At this exact time in my life, I exercise with all of these motivations in mind -- plus a few more. I like to sweat and know I am accomplishing a physical feat. I like the mental release I get when I push my body to perform. I like the time to myself, the loud music I hear on my MP3 player, and the results I see from a little bit of hard work. And lately -- as a result of a new weight training program -- I know I am benefiting my body more than ever before.

The following are just seven of the many gifts that come from weight training. Gifts that will make me a happier, healthier cancer survivor.

Noticeable physical results -- Mostly, walking and occasional jogging have been my methods of exercise. And I've seen results from this type of workout -- leaner legs, more defined calf muscles, and the knowledge that I am increasing my cardiovascular health, as confirmed by the technician who performed an ultrasound on my heart in preparation for my Herceptin treatment for breast cancer. He told me he could tell I exercised regularly because of my low resting heart rate. But until I started weight training a few months ago, I never witnessed quick results. Yet after a few weeks of resistance exercise -- lifting 20-pound weights for my arms, shoulders, back, and chest -- I could see definition and tone that clearly would not have resulted from my purely cardio workouts.

Improved strength and endurance -- Lunges and squats and jumping with resistance bands have strengthened my legs. Lifting weights has strengthened my arms -- and I can now lift heavier weights than when I first started my new routine. I can do more push-ups now too -- not girl push-ups on my knees but real push-ups -- than I ever could have imagined doing when I could barely lower my own body weight and would crash to the floor on my stomach. My strength has improved. My endurance has improved. I feel more powerful.

Increased energy -- Fatigue (or maybe it's laziness) sometimes prevents me from happily jumping up to begin exercising. But when I push myself and exert myself and get lost in my exercise routine, my energy returns -- and not just during my workout but for some time afterwards too. Some say energy increases from strength training because it contributes to loss of fat which means we have less to lug around each day.

Burning of more calories -- Weight training raises basal metabolism which causes more calorie burning over a 24-hour period of time. Calories even burn during sleep as a result of weight training.  For every additional pound of muscle you gain, your body burns 50 extra calories every day -- 50 more calories than the few hundred that might burn from aerobic exercise. Research shows that regular resistance training can increase your Basal Metabolic Rate by 15%. So for someone who burns 2000 calories per day, that's upwards of 300 extra calories burned every single day. 

Decreased onset of illness -- Weight training can reduce the risk of adult onset diabetes and the risk for developing colon cancer and can improve the functioning of the immune system and the efficiency of the heart. It decreases the risk of low-back injuries, decreases resting blood pressure, increases good cholesterol (HDL), and improves posture. The list goes on -- and so does healthy living if weight training becomes a way of life. As a young person already having experienced a life-threatening illness, this comforts me.

Prevention of osteoporosis -- My recent bone density test revealed that I am not at this moment at risk for developing osteoporosis. I don't want this to change. Strength training can help me maintain this status because it can significantly increase bone mineral density -- which is important because we naturally lose bone density as we age. Strength training helps protect against osteoporosis. And age should not be a deterrent. Individuals who begin training late in life -- at age 65, for example -- can restore bone loss.

Improved outlook on life -- As a result of toning and shaping my body, burning calories, enjoying greater strength and energy, and working toward a disease-free future, weight training gives me an improved outlook on life. And weight training has recently been reported to significantly improve the quality of life of women recently treated for breast cancer. A May 2006 study indicates six months of twice weekly exercise was enough to improve the overall physical and emotional condition of patients.

Twice weekly is my weight training goal. I will continue to walk and run -- and bike on occasion too -- but strength training will be my priority. Because health is a priority.

Donation of hair can bring shear joy to children

A few years ago -- I can't remember exactly when -- I cut bunches of red wavy locks from my friend's head. I tied Amber's thick hair into one big ponytail, and I cut away. It was an extreme haircut for sure. Amber's long hairstyle was transformed into a shoulder-length bob, and for good reason.

Amber sent her 10-inch ponytail to Locks of Love, a non-profit organization that creates human hair wigs and hairpieces from donated hair and gives them to children under the age of 18 who have lost their hair due a medical condition. This was the first time I'd heard of Locks of Love, and I've since met many others who have purposely grown their hair in order to donate it. I have a neighbor who has done it three or four times now. I know two teenage brothers who have cut their long, dark hair for this great cause. And I've known toddlers whose parents have waited for that first haircut until 10 inches could be cut.

Ten inches is the magic number. Once tied into a ponytail, there must be 10 inches of hair hanging beneath the rubber band. The ponytail is cut off and what remains can be cut into a new style. Locks of Love provides the procedures for mailing the hair, and the details can be found on the Locks of Love website.

I was bald this time last year -- after receiving four rounds of toxic chemotherapy for breast cancer -- and I know how devastating hair loss can be. It affected my self-esteem, and I can only imagine how it affects children whose self-esteem is just forming.

You might consider donating your hair so that a child's confidence can be restored during a time that is so difficult and challenging. I will consider it too -- but I must say that for now, I am enjoying watching my new short, brown, curly hair grow and grow and grow.

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