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Posts with tag activity

Lower insulin levels cut breast cancer recurrence

Researchers at the Dana-Farber Cancer Institute in Boston say exercise helps combat breast cancer. Not the first time we've heard this fact. But these same researchers have something new to say -- about the reason physical activity lowers the risk of breast cancer recurrence.

Jennifer Ligibel, MD, of Dana-Farber, reports that exercise lowers levels of the hormone insulin in the bloodstream. This is significant because there appears to be an association between relatively high levels of insulin, seen in obese and sedentary people, and an increased risk of breast cancer recurrence and breast cancer-related death.

"We know that women who are overweight at the time of breast cancer diagnosis have a higher risk of recurrence than lean women, but the reasons for this have not been clear," said Ligibel.

Continue reading Lower insulin levels cut breast cancer recurrence

Thought for the Day: Can cancer patients fight fatigue with activity?

Exhausted, weary, tired, lethargic -- cancer patients are all this and more when undergoing treatment, and it's a problem that may be fixed with some light activity. While rest is encouraged, it's now thought that the overwhelming fatigue experienced by those with cancer can be alleviated with activity, at least according to this video. Don't get me wrong .... you don't need to run an Ironman marathon or anything, but how about going for a walk, or doing a few light resistance moves?

Think about this:

A few gentle activities can help boost your energy, and can have positive systemic benefits in your body that hopefully will help your body fight the disease. Dick, the prostate cancer patient in the video, is part of a study to prove the benefits of exercise in cancer patients and he believes that his lack of fatigue is a result of his staying active during treatment.

What do you think? Should you take it easy or get up and about?

Cancer treatment: One size does not fit all

Theranostics Health LLC is a company that was formed by George Mason University cancer researchers Dr. Lance Liotta and Emanuel Petricoin.

The company plans to tailor cancer treatments to individual patients based on proteomics, the study of proteins. Proteins play a central role in our bodies. Understanding the structure and function of each protein and its complexities of protein interactions can be critical for developing the most effective diagnostic techniques and disease treatments in the future.

Information about protein activity in tumors can allow doctors to choose the best drugs to kill the cancer cells. President and CEO of the company Joseph Reilly said "The physicians will then be provided a new class of information about that patients' individual cancer. This will enable the physician to tailor the therapy based on the individual patients' tumor."

One size fits all for cancer treatment is hopefully on its way out. We need to prescribe the right therapy to the right patient. This will increase treatment success rates and also spare patients unnecessary toxicity from chemotherapy drugs that would be unsuitable for their tumor.

Viruses and cancer

Discoveries have linked certain viruses to cancer growth. The hepatitis B virus is related to liver cancer. Women who develop cervical cancer have had a human papilloma virus (HPV) infection but not all women with HPV infection will develop cervical cancer. Stomach ulcers are likely caused by Helicobactor pylori, or H. pylori a bacteria and the ulcers can grow into cancer. Viruses attack cells in the body and once these cells are corrupted they begin to grow uncontrollably, eventually leading to cancer.

With these discoveries leads us to the knowledge that protecting the immune system in the body and keeping viruses at bay, is important in preventing cancer. Viruses enter the body through everyday activities like eating, breathing and sexual activity. Eating well, exercising and avoiding alcohol and cigarettes are good ways to keep your body's natural defenses functioning at their best. Staying protected with condoms during sexual intercourse helps protect you from sexually transmitted viruses and diseases. Learning healthy life style habits is the beginning of keeping cancer at bay. Focusing on nutrition, exercise, body weight, keeping toxins out of our bodies and our home environment ,and lowering stress will all help boost the immune system.

Prescription for good health -- get a dog

A U.K. researcher confirms what many dog lovers already know -- dogs are good for your health.

Apparently, dog owners are generally healthier than non-pet-owners. They have lower blood pressure and cholesterol, suffer fewer minor ailments, and stray from serious medical problems too. Dogs can prevent their owners from getting sick, help them recover more quickly when they do fall ill, and they can even warn of cancer, heart attack, epileptic seizures, and hypoglycemia, says Dr. Deborah Wells from the Canine Behaviour Centre of Queens University in Northern Ireland.

Wells, whose study is published in the British Journal of Health Psychology, says dogs buffer us from stress -- a well-known cause of illness -- and promote general well-being. Owning a dog leads to increased physical activity and increases development of social interactions -- both of which minimize stress and contribute to human health.

While Wells found those who own both dogs and cats benefit from their pets, dog owners enjoy improved health for much longer than cat owners.

Connecting the clues in Australia cancer cluster

The ABC building in the Brisbane suburb of Toowong -- subject of a December 2006 post -- has been officially vacated following an investigation that turned up a cancer cluster among female employees.

Over the past 11 years, 10 women from this one building have been diagnosed with breast cancer. Eight of the women worked in the ABC newsroom, and most had been there for more than five years. The breast cancer risk for these women was six times higher than for the general population of women in the area. And while the investigation continues and clues are beginning to connect, the big question -- Why? -- has still not been answered.

It has been determined it is highly unlikely the increase in breast cancer was caused by exposure to radio frequency, low frequency electromagnetic radiation, or chemical contamination. According to experts, had any of these factors been at play, there would have been a rise in cancer among male employees as well as female employees. Therefore, it appears something specific to women has caused this cluster.

Perhaps clues will emerge from an analysis of lifestyle influences -- like smoking, diet, and alcohol and medication use -- and already women have answered questions pertaining to body weight, height, level of physical activity, and reproductive history.

One common theme among women is the use of oral contraceptives for periods varying from two to 18 years. Other interesting findings include the average number of babies born to the women -- 1.6 -- and the breastfeeding practices of the women -- each woman with a child breastfed for an average of 2.3 to 12 months -- and the educational background of the group -- of the 10 women, six have college degrees.

Experts says these are important factors. Early puberty, late menopause, lack of breastfeeding, use of oral contraceptives, and the trend of older mothers having fewer babies all can influence breast cancer risk. And so can level of education. Research shows increased rates of breast cancer in women with white collar jobs -- which is related to socioeconomic status and late childbearing.

Everything is important really -- because as breast cancer rates continue to skyrocket, all possible reasons need to be considered.

One in eight women in Australia will be diagnosed with breast cancer before the age of 85. About 13,261 women were diagnosed with breast cancer in 2006. And it is predicted that 14,818 will be diagnosed in 2011.

Evidence stacks up in favor of exercise

The evidence is stacking up. And it seems almost everyone will soon agree that exercising can help prevent a return of cancer for those who have already done battle with the disease.

The American Cancer Society just issued a report updating nutrition and physical activity recommendations for cancer survivors. Exercise tops the list of recommendations.

For some types of cancers, exercising for just one to three hours per week can lower the risk of cancer recurrence and death, as well as death from all causes. Exercise has also been shown to improve fitness, diminish fatigue, and boost quality of life for survivors.

The report also states that while a vegetarian diet may be healthful in some ways, there is no direct proof that the diet can prevent cancer recurrence. Survivors who do choose a vegetarian lifestyle should ensure they are receiving an adequate intake of nutrients.

A standard multivitamin and mineral supplement equivalent to 100 percent of the Daily Value can help survivors meet their nutrient needs when it's difficult to eat a healthy diet. Some supplements -- such as those high in folic acid or antioxidants -- may be harmful during cancer treatment.

According to the American Cancer Society, food safety is especially important for cancer survivors, especially during treatment that causes immunosuppression.

And then there's alcohol. Alcohol can affect the risk for new primary cancers and should be used sparingly -- or not at all.

Magical food media reports misleading consumers

Writer Richard Morris of www.breadandmoney.com coins the word nutritainment in a recent article about foods that are hyped to magically make us healthy -- foods that can cancel out cancer and wipe out heart disease. Nutritainment is nutritional news delivered in entertainment-like fashion, designed to urge consumers to buy into the latest, greatest super foods. Yet making small changes in diet -- what most consumers will do -- to incorporate these so-called powerful products is unlikely to do much good, Morris says. And he offers some thoughts on why the media continues to force this news down our throats and why we continue falling for their tactics.

Morris says human nature and marketplace economics motivate those engaged in nutritional sciences to strive for media attention and exposure. As a result, bits and pieces of nutritional studies make their way to medical journals and then land in media's lap through press releases. Some will even ghostwrite nutrition articles to promote products. These articles end up in the hands of the media and spread like wildfire to the public, in as-is format. Consumers may be left with the notion that these bits and pieces are important, relevant, non-biased research -- when this is not the case.

Morris says knowledgeable health experts who have the time to accurately report on important nutrition news are scarce. And when they do have time to share words of wisdom that really do matter, the packaging of the news is often technical and not so sensational. A headline that reads, Pomegranate juice packs power to prevent cancer will bury a scientific -- yet more accurate -- headline. Catchy headlines grab readers, and readers buy products. But headlines can be misleading -- and pomegranate juice alone is not likely to have many health benefits.

There are also issues with advertising and editorial content, according to Morris, who compares overall good nutrition to car maintenance. "Just like changing the air freshener in your car won't prevent a breakdown if the car desperately needs a tune-up, adding one item of magical food to your diet won't protect you from a breakdown either," he says and shares that a complete dietary makeover is what's necessary for good health -- that and stress reduction, physical activity, emotional balance, and life fulfillment. A quick dose of pomegranate juice may not do the trick. But a steady, consistent dose of these items will.

Sunday Seven: Seven ways breast cancer research is on a roll

If we made no further progress in breast cancer research from this day on, the number of women dying from breast cancer five years from now would still drop substantially because we've progressed so much over the past few years, says MD Eric Winer in the October 2006 issue of Oprah magazine. Winer, director of the Breast Oncology Center at Dana-Farber Cancer Institute and associate professor of medicine at Harvard Medical School, is right. There has been a lot of progress. Breast cancer research is on a roll. And here are seven reasons why.

Continue reading Sunday Seven: Seven ways breast cancer research is on a roll

Lung cancer breathing techniques can help us all relax

The Lung Cancer Alliance -- the only national non-profit organization dedicated entirely to lung cancer patient support and advocacy -- asked pulmonary clinical nurse specialist Donna Wilson to help educate the lung cancer community about healthy breathing. Wilson agreed and her breathing tips, available on podcast, are intended to relieve shortness of breath related to pain or activity. Her three breathing techniques -- detailed here -- are simple, easy-to-understand, and truly relaxing.

Before beginning this series of breathing exercises, stop whatever you are doing and sit down or lean against a wall.
  • Place chin to your chest to relax your neck muscles. Breathe 10 short bursts of air in and out of your lips. As you expel air, neck and chest muscles should relax.
  • Place chin to your chest. Breathe three times in through your nose and out through your mouth.
  • Place chin to your chest. Close your mouth, and breathe four times in and out only through your nose.
After completing these exercises, lift your head, breathe normally, and let your shoulders relax. In a few minutes, your entire body should start to relax -- and shortness of breath will resolve.

I don't have lung cancer -- but I do have moments of anxiety and panic. So I plan to save these tips. And I plan to use them. And I plan to share them. Because we all can benefit from a dose of relaxation.

Liver cancer treated with Nexavar shows response in some patients

When cancer originates in the liver it is called hepatocellular carcinoma (HCC). In advanced HCC the cancer has spread to distant places in the body.

Biological pathways that are believed to be associated with cancer growth and spread can be targeted by Nexavar. A clinical trial was conducted consisting of 137 patients who have received no prior therapy and were unable to undergo the surgical removal of their cancer.

According to the article in the Journal of Clinical Oncology, Nexavar may provide anticancer activity in some patients with liver cancer and is well tolerated.

Also, a measure of 18 genes that were identified can help predict who will benefit from the drug Nexavar. Future clinical trials are being planned to evaluate the use of Nexavar in advanced hepatocellular carcinoma patients.

Helping St. Jude's Children's Hospital never tasted so good

Chili's restaurant is the place to be on September 25 -- because 100 percent of profits earned on this day will go to St. Jude's Children's Research Hospital -- the only hospital for sick children that does not require anyone to pay for treatment. So fundraising is key -- and Chili's has cooked up all sorts of creative ways to help conquer cancer in children.

Besides Donate All Our Profits Day, Chili's is sponsoring a program called Creativity for a Cause -- where customers make a donation and then color a rendering of a pepper. The coloring sheets are displayed at participating restaurants in a chain-like fashion, hanging from the ceilings. Create a Pepper gift cards are also available. For every $25 spent on gift cards, Chili's will donate $1 to St. Jude's. And t-shirts -- black with a white pepper gracing the front -- can be purchased for $12. Kids can even have fun on-line with Chili's crafty creations, including an interactive pepper coloring activity.

All this fundraising goes hand in hand with the development of the Chili's Care Center -- a St. Jude's state-of-the-art building dedicated to groundbreaking research on brain tumors. The center is scheduled to open in Fall 2007 -- thanks to Chili's professionals who over the course of 10 years have donated a historic $50 million to St. Jude's.

Condoms required: semen speeds the spread of cervical cancer

Women diagnosed with cervical or uterine cancer, or are at higher risk for these cancers, need to require their sexual partners to wear a condom during sex, as semen appears to speed up the progression of cervical and uterine cancer, according to the results of a study done by UK Medical Research Council researchers.

Researchers found that high levels of prostaglandin present in semen might promote and fuel the growth of certain cancers for women. The hormone prostaglandin is produced by the reproductive glands of women and the levels of prostaglandin primarily regulates how much the uterine lining thickens and sheds each month. Semen contains a prostaglandin concentration 1,000 times higher than women normally produce in their own bodies.

The introduction of semen might promote cervical cancer and uterine cancer, as cervical and uterine cancer cells have prostaglandin receptor molecules on their surfaces. While it is known the human papilloma virus (HPV) might lead to cervical cancer, the researchers feel there might be other factors that fuel the development and spread of these cancers for women. Many women are infected with HPV at some point in their life, but not all women will go on to develop cervical cancer from the infection.

Young girls shun the sun at higher cancer risk and bone loss

Between pale is the new tan and cultural or religious beliefs that require young girls to wear clothing that covers all skin areas and young girls who are restricted from outdoor activities, adolescent girls are paying the price in insufficient levels of vitamin D needed for peak bone mass -- increasing the risk of osteoporosis fracture later in life. By shunning the sun they might be decreasing the risks for skin cancer, but they are increasing the risks for 16 other cancers.

Of the 51 healthy girls tested, Saint Mary's Hospital for Women and Children in Manchester researchers found 73 percent were vitamin D deficient, and 17 percent were severely deficient in vitamin D.

Lack of a sufficient level of vitamin D was in direct correlation to the lack of exposure to sun and not to dietary intake. "This is in keeping with the fact that the main source of vitamin D is that produced by the action of solar ultraviolet B radiation acting on 7-dehydrocholesterol in skin," the team explains. "Only small amounts are obtained from dietary sources."

Aside from encouraging more outdoor activity for these young girls, the researchers stated that it remains to be determined how to meet the needs of older children and adolescents from cultures that avoid sunlight.

Cervical cancer vaccine for boys and men

Almost all conversation and approval efforts regarding Gardasil, the new vaccine that prevents cervical cancer, has been about girls and women. Medical experts and researchers are recommending that boys and men receive the cervical cancer vaccine too. They suggest this is a necessary step if there is to be an effective elimination of cervical cancer originating from infection of human papillomavirus (HPV).

At this time, the recent approval for the vaccine only speaks to the use for girls aged 9 to 26. But both women and men become infected with HPV, and it does not make sense that only one half of the population at risk for infection are being vaccinated.

According to the Centers for Disease Control and Prevention (CDC) almost 80 percent of U.S. women by age 50 will be exposed to one of the 100 strains of HPV, known to cause genital warts and cervical, vulva and vaginal cancer in women.

"Vaccine prevention strategies work when they are applied in a gender-neutral fashion," stated Bradley Monk, author of the commentary addressing this issue published in the journal Obstetrics and Gynecology. "For example, polio, measles, tetanus, pertussis, diphtheria, rubella, mumps, and Haemophilus influenza B have been nearly eliminated in the United States as a result of this strategy."

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