University of Pittsburgh researchers are studying the potential use of stem cells, that come from the fat in our own bodies, for breast cancer reconstruction. Breast cancer survivors may one day be able to avoid the prospect of invasive breast surgeries. This approach uses the stem cells to regenerate tissue to develop into different specialized cell types.
When the fat-derived stem cells are injected under the skin in a rat model, the cellular combination eventually formed what the researchers describe as a mound of tissue. Dr. J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the University of Pittsburgh School of Medicine, said "The surgical options for breast reconstruction involve either the use of implants or a procedure whereby fat tissue is taken from another part of the body is shaped into the form of a breast. Neither is ideal nor without risk. The use of adipose or fat derived stem cells may represent a better solution for soft tissue reconstruction in breast cancer patients".
Dr. Rubin has been given a three year grant from the National Cancer Institute to further explore this unique approach.
Recent research indicates that obesity makes ovarian cancer deadlier and more likely to recur. According to physician and senior author of the study, Dr. Andrew J. Li of the Cedars-Sinai Medical Center, maintaining ideal body weight is important for many reasons. This is just one more reason to reduce obesity -- because obese women suffering from advanced ovarian cancer are more likely to die than women at healthy weights. They also suffer recurrences more quickly. On average, women in the study considered overweight or obese saw an average of 16 months before recurrence while those considered underweight or at a healthy weight saw 25 months.
