Hot flashes can be a lingering side effect for many breast cancer survivors. The hot flashes occur when changes in hormone levels interfere with the body's ability to regulate its temperature.

Hot flashes can affect younger women treated with chemotherapy (which can shut down their ovaries), and also is one of the main side effects of the commonly prescribed hormone therapies, such as tamoxifen or an aromatase inhibitor such as Arimidex.

Hormone replacement therapy can be used to control hot flashes, but breast cancer survivors are recommended not use them because of concerns the hormones may increase the risk of their breast cancer returning.

An article published in the Annals of Oncology reported on a German study that was conducted to compare Effexor and clonidine therapy. Effexor is an antidepressant and clonidine is a drug used to treat high blood pressure.

The researchers concluded that Effexor significantly reduces the frequency of hot flashes compared with Catapres (clonidine) among patients with breast cancer who suffer from at least two hot flashes a day.

There are other anti-depressive agents that also reduce the amount of hot flashes throughout the day. Talk to your doctor to see if any of these drugs can give you some relief.

The latest Phase III study of Roche's cancer treatment Xeloda -- featuring 627 previously treated colorectal patients -- has reached its primary endpoint of progression-free survival.

Study results show that the chemotherapy combination XELOX (Xeloda plus oxaliplatin) was as effective as the combination FOLFOX-4 (infused 5-FU/leucovorin plus oxaliplatin) in delaying disease progression -- a result that will be used in worldwide submissions of the drug.

Xeloda, an oral chemotherapy agent that can be taken at home, is already used in previously untreated colorectal cancer patients. It has also been approved for treatment of early stage colon cancer and for breast cancer that has spread to other parts of the body.

Suzanne Pleshette's agent reported on Friday that the actress is currently undergoing treatment for lung cancer. The cancer was discovered during a routine X-ray and was no bigger than a grain of sand. Pleshette apparently feels very lucky and is in great spirits as she receives outpatient chemotherapy at Cedars-Sinai Medical Center -- where the cancer was diagnosed.

Kids can be so positive and encouraging, even in the face of sickness. Now today my kids have just a simple sickness -- nothing life-threatening -- that I'm sure will pass in a day or so. They are throwing up every content of their little tummies -- even sips of water -- and they are pale and lethargic and run-down. But still, they have hope for a brighter tomorrow. This morning, five-year-old Joey said to me while resting in my bed and just after he threw up , "this is just the good getting rid of the bad." He went on to explain how the good in our bodies knows when to push the bad out. And this is what is happening to him today, he said. He is throwing up the bad so the good can take over. Simple. Easy. Makes sense.

I never saw my own sickness like this. Instead of visualizing chemotherapy as a good agent that kills bad cells, I was repulsed by the horrific liquids that poisoned my body. I knew of people who were able to turn chemotherapy into a Pac-Man game -- with Pac Man chomping away at the cancer cells and leaving nothing but healthy cells to thrive. And I knew people who were relieved to feel sick because it meant the chemotherapy was working. I never saw it like this -- although I do know that chemotherapy may have saved me from a life with cancer. I was discouraged by chemotherapy. I had a negative attitude about it, and I had to really gear up for all of my infusions. I still -- more than one year later -- cannot eat anything I ate on my chemo days. The mere thought of these foods makes me feel ill.

A pediatrician friend of mine told me that kids with cancer tend to be positive. There are a few old souls, she said, but for the most part, they continue to tackle life with spirit and adventure and simplicity. Like my boys today who are peacefully napping at the moment so everything good in their bodies can come back with a vengeance.

Apple CEO Steve Jobs delivered a commencement speech at Stanford University on June 12, 2005. It was about following curiosity and intuition, about looking back and connecting the dots in life, about beginnings and endings, about death. Jobs, a survivor of pancreatic cancer, knows a thing or two about facing death. And the words he chose to relate his life-threatening experience to a crowd full of hopeful graduates are powerful and inspiring. I could paraphrase his message -- but surely something would be lost in my translation. So here is a bit of what he said -- word for word.

Herceptin -- a targeted breast cancer drug used to treat women who are Her2 positive -- has received rave reviews and has shown great promise in cutting down on recurrence of this aggressive form of breast cancer. Given over the course of 52 weeks, Herceptin is wondrous for its lack of short-term side effects. There is no hair loss, no compromise of blood counts, no significant sickness. For me, fatigue may have resulted from this treatment -- but it's unclear to me really whether it was the Herceptin or the two small boys I have living in my house that most contributed to my occasional exhaustion. Regardless, I functioned well while receiving Herceptin for the past year -- and I did not suffer anything more than a twinge of pain when my port was accessed for each treatment. In the short term, I have fared well. In the long term, the jury is still out.

Ian Copeland, music booking agent who represented acts like Joan Jett, R.E.M., Squeeze, The Police, B-52s, Ramones, and the Cure; who wrote Wild Thing, and was brother to Police drummer Stewart Copeland, has lost his life to skin cancer.

Copeland wrote his autobiographical memoir, Wild Thing: The Backstage, on the Road, in the Studio, Off the Charts Memoirs of Ian Copeland, chronicling his early life as the son of a father who was both jazz musician and CIA intelligence officer and a mother who was both spy and archeologist -- to his wild adventures as a rock music agent. He spent most of his adult life working in the music industry.

"Everybody has always said my brother Ian would have been a more charismatic rock star than anybody he has ever represented," Stewart Copeland told People magazine in 1995. "But instead of shouting to a sea of faces, he'd much rather sit at the dinner table and regale everybody personally." Copeland was 57.

Photo: Ian Copeland (left) with brothers Stewart (centre) and Miles (right)