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Posts with tag arthritis

Thought for the Day: Pet chemotherapy not so out there

More than 47 percent of people view their pets as family members, according to a 2002 American Veterinary Medical Association survey. It makes sense then that people are routinely treating their pets for ailments that might strike a family member -- like arthritis, heart disease, diabetes, allergies, dementia, obesity, and yes, cancer.

New studies show that Americans are stuffing their pets with more drugs than ever before. They are medicating their dogs, cats, and sometimes other pets as much as they medicate themselves -- and they are doing it with many of the same human drugs they use for themselves, like steroids for inflammation, antibiotics for infection, anti-depressants for anxiety, and even new slendering drugs for obesity.

It's a big market -- pharmaceuticals for pets -- and for those who love their pets so much they can't let go, going to extremes is worth every penny.

Think about this:
  • For dogs and cats alone, Americans spent $2.9 billion on pet drugs in 2005. While this is equal to only one percent of human drug sales, the market has grown by half since 2000.
  • The U.S. Food and Drug Administration (FDA) has approved more than 40 new pet drugs in the past five years.
  • A single three-month course of pet chemotherapy can cost $3,000 -- and chemotherapy doesn't typically extend the life of an animal as much as it soothes symptoms of the disease.
  • Health insurance for pets was nearly invisible in 2002 but has gained popularity over the past few years. Premiums can cost $30 per month, and the total market is expected to climb to $500 million in the next five years.
  • Some human drugs leave pets with unexpected, sometimes deadly, side effects. The drug Rimadyl, made by Pfizer and used as a treatment for dogs with arthritis, has been shown to cause kidney and liver damage in some animals. More than 3,000 pet deaths have been attributed to this drug.
  • Some question the priorities of a society that allows for medically treating pets like they are humans. Dianne Dunning, an ethicist at N.C. State's vet school is concerned that millions of animals are lost, unwanted, and euthanized while millions are spent on pet medicines. David Rothman, an expert in medicine's role in society from Columbia University, says, "If you can't get malaria drugs in some Third World countries, what are we doing with chemotherapy for cats?"
  • Others don't flinch at the expense it requires to keep their pets alive. One man, whose dog was expected to die of lymphoma within weeks, still enjoys the company of his pet some two years later. Chemotherapy saved the dog's life and when asked if he thinks the drugs are too expensive, this man says NO -- because his dog is still here.

Link found between arthritis and cancer

British researchers have found a connection between inflammatory polyarthritis, rheumatoid arthritis, and cancer. The connection -- a 40 percent increase in cancer mortality in patients with both arthritis conditions.

This is a striking finding, say researchers, whose study is published in the March issue of Arthritis & Rheumatism.

"The results of this study demonstrated that five-year cancer survival in patients with IP is substantially reduced in comparison with that in the general population, even after adjusting for differences in age, sex, and cancer site, whereas the overall cancer incidence does not seem to be increased," says study leader Dr. Alan Silman, an epidemiologist with the University of Manchester.

Mistletoe extract: safe or dangerous cancer treatment?

According to a CBC News report, ancient druids believed mistletoe had magical properties because of the way it grows, never touching the ground and without taking nourishment from the earth. However, University Hospital of Wales in Cardiff researchers are warning there is nothing magical about the use of mistletoe extract for the treatment of cancer, and in fact, it can cause harm.

Serious side effects from the injection of mistletoe extract have been reported in the Christmas issue of the British Medical Journal, including a case concerning a 61-year-old woman who had a tumor-like growth develop under her skin, brought on when she self-injected herself with mistletoe extract. The researchers warn that the use of mistletoe extract has been shown to cause a severe allergic reaction, breathing difficulties, joint pain and kidney failure. Some studies have shown that mistletoe might actually lead to cancer growth.

Edzard Ernst, a professor of complementary medicine at the Universities of Exeter and Plymouth is quoted as saying, "The idea that mistletoe may help treat cancer is based on that the idea that mistletoe, like cancer, is a parasitic growth that eventually kills its host." The researchers of this published study indicated that there are over 30 mistletoe extract preparations available in Europe, and its use by cancer patients is well-known.

From another source, the National Cancer Institute's overview of mistletoe includes the following:
  • Mistletoe is a plant that grows on several types of trees and has been used since ancient times to treat many ailments.
  • Mistletoe extract has been shown to kill cancer cells in the laboratory and to boost the immune system.
  • Animal studies have suggested that mistletoe may be useful in decreasing the side effects of standard anticancer therapy.
  • Many human studies using mistletoe to treat cancer have been done in Europe with unclear results, and a few clinical trials in the United States and abroad are in progress.
  • Very few bad side effects have been reported from the use of mistletoe extract, though mistletoe plants and berries are poisonous to humans.
  • The U.S. Food and Drug Administration (FDA) has not approved mistletoe as a treatment for cancer or any other medical condition.
To read detailed information about the highlighted overview, visit the NCI's FAQ about mistletoe.

Uncertain about red meat

Children and teenagers -- mostly girls -- need zinc, a mineral important for maintaining healthy immune systems and healthy skin and for preventing colds and infections. Yet half of all teenage girls have zinc deficiencies.

Red meat is the most effective way of channeling zinc into the body. Perhaps these young girls are eating red meat less than two times per week -- a practice research shows can contribute to zinc deficiencies.

Iron is vital for good health. Menstruating women need it. The elderly need it. Pregnant women need it. And children need it too. But many lack healthy levels of iron.

Red meat contains a lot of iron. And while iron also comes from vegetable sources, meat contains more iron than most foods and is best utilized by the body in this form.

Red meat also contains B vitamins, phosphorus, potassium, magnesium, selenium -- and protein, critical for muscle and organ health. Protein from red meat is complete, meaning it contains all the amino acids the body cannot make on its own. Protein helps the body repair and renew.

There is definitely a good side to eating red meat. There is also a bad side.

Red meat has been linked to incidences of bowel cancer, breast cancer, heart disease, Alzheimer's disease, osteoporosis, arthritis, high cholesterol, clogged arteries, and food poisoning.

Experts say the controversy surrounding red meat comes down to the type of meat we are eating -- and how we are eating it.

There are three official red meats -- pork, lamb, and beef. Pork is the leanest, lamb is the fattiest, and beef is the most nutritious. Red meat is typically high in saturated fats and bad cholesterol. But lean beef is fairly healthy -- if it's not treated with hormones and is truly free from excess fat. The more white you see, the more fat you get.

So here is the trick for all meat-eaters out there -- choose lean meats, seek nutritious cuts of meat, avoid hormone-treated products, steer clear of processed meats (these include more additives and fats than simple cuts of pork, lamb, and beef), read labels carefully, make meat just one component of a balanced diet, and brace yourself for more research and study and discussion that will undoubtedly conclude that meat is good for us. And bad for us too.

Marijuana: Physician who allegedly sold starter plants to patients is awaiting trial

Dr. Mollie Fry, who estimates she has issued thousands of cannabis recommendations since setting up her thriving practice northeast of Sacramento in 1999, was indicted last year on felony charges of conspiring to distribute marijuana. Mollie claims she is being prosecuted unfairly because she recommended pot for patients under California's medical marijuana law.

Medical marijuana advocates estimate that about 1,500 doctors, mostly oncologists and AIDS specialists, have authorized pot for at least one patient. California's medical marijuana law, also known as Proposition 215, named ailments for which marijuana might prove helpful in easing symptoms: cancer, anorexia, AIDS, glaucoma, arthritis and migraines.

Frank Lucindo, a Berkeley physician devotes about thirty percent of his time to working with medical marijuana patients says " pot docs are being held to higher standards than doctors who prescribe lots of Viagra, prescription painkillers and other abused medications".

Fry thought that telling her patients how to relieve pain, depression and nausea was the right thing to do. She said "What did I take an oath to do? To do no harm and to alleviate pain and suffering. I'm going to be true to my oath, and I'm even willing to go to prison for it."

FDA warning popular prescription drugs counterfeit

Prescription drugs purchased online from Canadian pharmacies were intercepted before they reached the US, and after preliminary laboratory tests were found to be counterfeit. The U.S. Food and Drug Administration (FDA) is warning consumers who may have obtained prescription drugs from Mediplan Prescription Plus Pharmacy or Mediplan Global Health in Manitoba, Canada not to take the medication as it may not be safe.

The drugs in question are Lipitor, Diovan, Actonel, Nexium, Hyzaar, Ezetrol or Zetia, Crestor, Celebrex, Arimidex, and Propecia. Most of the drugs are prescribed for cholesterol disorders and high blood pressure; Actonel for osteoporosis in postmenopausal women; Nexium for gastroesophageal reflux disease; Celebrex for arthritis-related pain; Propecia for male-pattern baldness and Arimidex is a breast cancer chemoprevention medication.

Interestingly, the FDA conducted an investigation last year and discovered that nearly half of the imported drugs they confiscated from four selected countries were shipped to fill orders that consumers believed they were placing with Canadian pharmacies. The drugs did not come from Canada. According to the FDA, 85 percent actually came from 27 other countries around the globe. Buyer beware.

Aspirin benefits prostate health for men

No one is suggesting that men start taking aspirin for prostate health if they are not already taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) for other reasons. However, Mayo Clinic researchers do say that men who are already taking a daily dose of aspirin might be enjoying a better level of prostate health. According to researchers, aspirin seems to prevent or delay an enlarged prostate that can lead to urinary difficulties such as frequent urination, trouble urinating, weak urine stream and an urgent need to urinate.

While the researchers cannot state why NSAIDs benefit prostate health for benign prostatic hyperplasia, previous research has indicated aspirin provides certain prostate cancer prevention benefits. Many older adults already take aspirin, or other NSAIDs, for heart health and arthritis, and taking aspirin now appears to offer another added benefit in prostate health for men. Aspirin is not without its downside. Researchers do warn that taking aspirin can lead to stomach ulcers. As with any drug, one has to weigh the risk against the benefit.

Pets: bone cancer in dogs and cats

Having a dog or cat or any other pet diagnosed with cancer is just as hard as having a friend or family member diagnosed. We have to determine the treatments and procedures since they can't speak up. A common cancer in dogs and cats is bone cancer. Osteosarcoma is the most common long bone tumor in dogs and cats. Often it is mistaken for arthritis or pulled muscles or stiffness in its early stages and so is not diagnosed sometimes until drastic measures have to take place. Cats and dogs differ in the way bone cancer matures and how treatment should be administered. Because of the rapid nature of osteosarcoma, treatment should be sought as soon as possible. The only trouble is that the most common sign -- lameness and pain -- usually happens when it is already taken firm hold.

Continue reading Pets: bone cancer in dogs and cats

Cancer drug linked to rotting jaws

Out of New Zealand comes reporting that four New Zealanders have suffered rotting jawbones after taking a bisphosphates medication prescribed to help prevent bone loss for patients suffering from osteoporosis and bone cancers. At least 15 Americans are suing Merck after developing breakdown of bone in the jaw due to taking Fosamax prescribed to strengthen bone and prevent bone loss.

According to the report, while the New Zealand patients were not taking the brand name drug, Fosamax, they were taking a similar version of the same drug. In total, about 2500 cases of rotting jaws have been reported. Merck is the same company who was forced to take Vioxx, an arthritis drug, off the market after a study showed it doubled the risk of heart attacks or strokes if patients took it for longer than 18 months. Perhaps we need to take a closer look into the medicine cabinet -- and start asking more questions -- before we rush to get a glass of water and down the newest approved pill. A new cancer drug is about to hit the market. Let's take a look.

Continue reading Cancer drug linked to rotting jaws

Arthritis drug triples cancer risk

Mayo Clinic researchers have released information from a recent study indicating that rheumatoid arthritis patients taking Humira or Remicade face triple the risk of developing skin, gastrointestinal, breast, lung tumors and lymphoma. In response to the new findings, Abbott Laboratories' Humira and Centocor's Remicade say the new study does not prove the medication is at fault, and they believe the research is flawed.

Dr. Eric Matteson, coauthor of the study, does say that the overall chance of developing cancer is small, and that the benefits for taking these medications have great benefit for rheumatoid arthritis sufferers. At the same time, he feels that patients should be made aware of the dangers -- to report any unusual symptoms to their doctor -- and to undergo annual cancer screenings recommended for the general public.

New help for chemotherapy fatigue

According to Ohio State University Comprehensive Cancer Center researchers, a drug prescribed for rheumatoid arthritis, etanercept, has been found to alleviate some of the fatigue and muscle-wasting cancer patients suffer while undergoing chemotherapy. The researchers explain that fatigue and muscle wasting associated with cancer are largely caused when immune cells release a substance known as tumor necrosis factor, TNF. Although TNF has been studied for its anti-cancer properties, recent studies indicate that TNF promotes tumor growth instead of slowing it down. These findings are based on a very small study involving 24 cancer patients. But, as the researchers point out, the chemotherapy-induced fatigue suffered by cancer patients can get in the way of continued chemotherapy. Won't it be nice when chemotherapy, as a cancer therapy, is a thing of the past -- replaced with cancer therapies that only target the cancer without damaging the healthy body.

Inflammation link between rheumatoid arthritis and cancer

Karolinska University Hospital in Stockholm researchers believe they have found the factor that leads patients who suffer severe rheumatoid arthritis, RA, to be at higher risk of developing lymphoma cancer. After analyzing the national register of nearly 75,000 patients diagnosed with RA, they were able to conclude that prolonged inflammatory activity, not any RA treatments, seems to be the link between the two diseases.

Medium RA activity led to an 8-fold increase in the risk for lymphoma, while high RA activity led to a 70-fold increase in lymphoma cancer risk. In addition, RA patients suffered pronounced, irreversible joint damage in the hands, feet, and knees in the last year leading up to a lymphoma cancer diagnosis. The researchers reported lymphoma cancer risk was interestingly low among patients who had received frequent corticosteroid injections in inflamed joints, indicating a possible lymphoma-protective role of potent anti-inflammatory drugs. They are able to speculate that aggressive anti-inflammatory treatment may reduce the lymphoma cancer risk by reducing cumulative RA inflammation.

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