Way to go Wake Forest University scientists -- for adding to the body of evidence connecting stress to illness and for reporting before anyone else that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to death.

Emotional stress contributes not only to the development of cancer, says lead researcher George Kulik, D.V.M., Ph.D, but it also reduces the effectiveness of cancer treatments.

Previous research shows levels of epinephrine, produced by the adrenal glands, are sharply increased during stressful situations and can stay elevated during long-term stress and depression.

During this study, published in the on-line Journal of Biological Chemistry, Kulik and colleagues found that a protein called BAD -- the cause of cell death -- becomes inactive when cancer cells are exposed to epinephrine.

This is huge for patients and researchers.

"It may be important for patients who have increased responses to stress to learn to manage the effects," said Kulik. "And, the results point to the possibility of developing an intervention to block the effects of epinephrine."

Actress Gwyneth Paltrow has lost five family members to cancer -- and she fears the disease may one day strike her. So she's taking action now and is trying to beat back the cancer curse that seems to loom over her loved ones.

Ever since losing her famous father in 2002 to throat cancer, Paltrow has been approaching life from a biological perspective.

"Cancer has been the curse of my family,"she said. "I am challenging these evil genes by natural means. I am convinced that by eating biological foods it is possible to avoid the growth of tumors. I began this crusade soon after my father's death. Since then the fight against tumors has been my mission."

Paltrow and her husband, Coldplay's Chris Martin, have embraced a strict vegetarian diet for their young family, and they hope their commitment to healthy eating will ward off the illness they fear may be headed right for them.

On December 8, 2006, I wrote about a Danish study investigating the possible link between cell phone use and cancer. This largest-ever study of it's kind put fears to rest. Cell phones do not cause cancer, said researchers who announced that cell phone users -- even long-term users -- are at no more risk of developing cancer than their non-cell phone using counterparts.

There's just no biological basis for concern about radio waves, reported the lead investigator of this study. But another newer study reports something entirely different.

Long-term mobile phone users are more likely to develop cancer -- brain cancer, on the side of the head where the phone is held -- according to the Radiation and Nuclear Safety Authority in Finland. It will all be detailed later this year in the International Journal of Cancer, but the general gist of the study is already circulating.

The study -- the second one to suggest an increased risk of cancer due to emissions from cell phones -- found that people who regularly used cell phones for more than 10 years were 40 percent more likely to develop nervous system tumors called gliomas. Comparisons were made between 1,521 people with gliomas and 3,301 people without the tumors. While no connections were initially made between the phones and cancer, a link was found when researchers specifically focused on those who had used their phones for more than 10 years.

Short-term use of cell phones has never been linked to cancer. That's good. But I tend to believe cell phones are going to become even more a staple of our technologically-driven lives than they are now. And so 10 years may actually be considered short-term one day -- which means we all may soon be at risk.

For now, until research becomes more conclusive, we get to pick and choose which study to stand behind. So take your pick -- and stay tuned for future scientific revelations.

Tampa's H. Lee Moffitt Cancer Center & Research Institute, the only comprehensive cancer center in Florida, has just partnered with Merck & Co., one of the world's largest drug companies, to develop personalized cancer treatments using a patient's genetic profile.

The two powerhouse entities will form a for-profit company called M2Gen on donated land near the University of South Florida. And in the span of just a few years, researchers plan to compile a database of tumor tissue and other medical information to determine why some patients respond to treatment while others do not. The database could house information on more than 30,000 patients within five years and will enable researchers to identify biological markers that could help doctors choose the most effective treatment based on the genetic make-up of each patient's tumor.

Blind treatment -- where everyone receives the same thing -- will be a thing of the past as tailor-made therapies replace the one-size-fits-all approach.

Florida Governor Jeb Bush says of the partnership that will create more than 170 high-paying jobs, "Man, I don't know if you can think of a better Christmas present than that."

According to new research published in the British Journal of Cancer, younger women diagnosed with ovarian cancer have a greater chance of surviving the disease for five years or more. Researchers at Stanford University in California looked at the records of more than 28,000 American women diagnosed with ovarian cancer between 1988 and 2001.

They researchers found that:

• Women diagnosed under the age of 60 were more likely to survive at least five years than women over 60.
• Women diagnosed under 30 generally had better survival rates, although the disease is rare in this group.
• Women diagnosed under 30, 79 percent were still alive at five years.
• Women diagnosed between 30 and 60 years the survival rate for five years was 59 percent.
• Women diagnosed over the age of 60 had a 35 percent survival rate at five years.

The researchers are not sure of the reasons for the differences in survival at this point. It could be that the younger women had their cancer detected sooner or it could be due to biological differences. The researchers think that understanding the differences in survival for different age groups may help to improve survival for all age groups in the future.

University of Texas M. D. Anderson Cancer Center researchers have confirmed what more than a few cancer patients have personally believed for some time now. Stress increases cancer growth and finding ways to relax and reduce stress is beneficial to cancer survivorship.

In a preclinical study carried out on mice with ovarian cancer, researchers found that cancerous tumors grew and spread faster when the mice were experiencing increased levels of stress. According to the researchers, the conclusion of this study is the first definitive link between psychological stress and the biological processes that make ovarian tumors grow and spread. It appears stress hormones bind to receptors directly on tumor cells and, in turn, stimulate new blood vessel growth and other factors that lead to faster and more aggressive tumors.

"The concept of stress hormone receptors directly driving cancer growth is very new," said Dr. Anil Sood, the study's senior author. "Not much had been known about how often these receptors are expressed in cancer, and more importantly, whether they had any functional significance. Our research opens a new area of investigation."

The good news in this -- besides the fact that this study begins to validate what cancer survivors have been saying for years in the personal belief of the link between stress and cancer -- is that stress can be controlled and reduced by lifestyle changes and medication. In fact, the researchers found a beta blocker heart medication effectively blocked the adverse effect stress hormones had on tumor growth.

This could open new areas of research. Indeed, Dr. Sood and his team will continue to research the role of stress in cancer and examine the effects of stress hormones on cancers besides ovarian cancer. To read more about the University of Texas M. D. Anderson Cancer Center preclinical study, go here.

Hey U.G.L.Y. Unique. Gifted. Lovable. You., an organization that develops self-esteem building tools for teens, asked celebrities to donate their laughter for a fundraising CD of contagious laughter called Laugh It Off. According to the president of Hey U.G.L.Y. Betty Hoeffner, "We know the healing powers of laughter and how it can improve health and relieve stress." Past research has shown, from a biological standpoint, that laughter and humor do have healing power.

Why a CD of celebrity laughter? "When we saw other charities asking celebrities to donate things like purses, shoes and even bras, we thought celebrities donating their laughter would be a perfect fit," explains Hoeffner. Produced and directed by award-winning filmmaker Rick Erwin, the 60-minute CD and includes the laughter of: Jimmy Neutron voice talent, Debi Derryberry; Emmy-award winning actor/comedian Ben Hollis; JBTV host, Jerry Bryant; and commercial voice talent, Richard Schoen; Saturday Night Live's Tim Kazurinsky; Frank Sinatra's opening act comedian, Tom Dreesen; nationally syndicated radio host, Mancow Muller; and Late Show with David Letterman regular, Bob Sarlatte. One woman wrote Hey U.G.L.Y. that her brother, who has cancer, listens to the CD three times a day and loves it.

Can laughter cure cancer? Not by itself -- but there are numerous studies that show laughter initiates a powerful biological process of feel-good healing chemicals that support and strengthen the immune system. We have done several posts here, here, here, here, here and here about the healing power of humor and the laughter associated with it.