Chemotherapy sent my blood counts spiraling on two separate occasions. Both times I landed in the hospital. And during my second stay, it took several daily injections of Neupogen -- a growth factor immunity drug -- to push my white blood counts from a low 1,200 to a whopping 58,000.The only side effect I suffered as a result of this drug was aching bones and joints. This was temporary and not such a big deal. What might be a big deal for breast cancer survivors like me, however, is the result of a new study suggesting there may be a risk of leukemia from these immunity boosting drugs.
These drugs, G-CSF (such as Neupogen) and GM-CSF (such as Leukine) may cause rare cases of leukemia, says Columbia University's Dawn Hersmand whose study is published in yesterday's Journal of the National Cancer Institute.
It's already been established that chemotherapy itself can cause leukemia. And Hersmand's study showed 1.04 percent of women who did not receive growth factors developed leukemia from chemotherapy alone. But 1.77 percent of women treated with G-CSF or GM-CSF developed the disease. While the drugs appear to statistically double the risk, the actual risk still remains quite small. And researchers say the benefits of the drug right now outweigh the risks.


I am in a slump. I feel tired and slow and unmotivated. And ever since October 14 -- when I ran in the 5K Making Strides Against Breast Cancer event -- I can't seem to find the inspiration to exercise. I am making myself do it -- here and there -- but my usual drive and push and spunk are missing. Typically, I crave exercise and feel lethargic if I don't accomplish some sort of daily physical challenge. But for the past week or so, I have no craving, no desire to walk or run or lift weights, no appetite for my usual fitness routine. I am just plain tired.
It's no secret exercise is beneficial for just about everyone. So it should come as no surprise that researchers reported Monday that moderate, regular exercise can help women combat some of the side effects of breast cancer radiation treatment.
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