Researchers at the Dana-Farber Cancer Institute in Boston say exercise helps combat breast cancer. Not the first time we've heard this fact. But these same researchers have something new to say -- about the reason physical activity lowers the risk of breast cancer recurrence.

Jennifer Ligibel, MD, of Dana-Farber, reports that exercise lowers levels of the hormone insulin in the bloodstream. This is significant because there appears to be an association between relatively high levels of insulin, seen in obese and sedentary people, and an increased risk of breast cancer recurrence and breast cancer-related death.

"We know that women who are overweight at the time of breast cancer diagnosis have a higher risk of recurrence than lean women, but the reasons for this have not been clear," said Ligibel.

The Boston Marathon takes place today. And one runner -- known to friends and family as Running Bear -- will run to raise money for brain tumor research. She's already collected more than $3,500.

Harvard student Sarah MacCarthy, 25, will run for her Uncle Tim, who is battling glioblastoma (GBM), the most aggressive form of the primary brain tumors known collectively as gliomas.

If Uncle Tim can fight for his life, MacCarthy can use her privilege of good health to make a difference -- even if it means stepping up her casual running to marathon standards.

The Brain Tumor Society will benefit from MacCarthy's determination. Dedicated to improving quality of life for patients, survivors, and families affected by this disease, BTS is committed to being a national leader in the quest for a cure.

It seems MacCarthy is pretty committed herself. To contribute to her efforts and check on her progress, click here.

OK, we all know young women get breast cancer. But the way some talk about the pair -- young women and the deadly disease -- it would seem finding a young one living with this type of cancer is like locating that needle in a haystack. Many a young woman -- like me -- have heard doctors and nurses and technicians and family and friends remark, "you are too young for the disease," and then dismiss cancer suspicions as needless worry.

The median age for women diagnosed with breast cancer is 65. But think about this fact, published in the Spring/Summer edition of Beyond: Live & Thrive After Breast Cancer.

More than 240,000 women in the United States age 40 and under are living with breast cancer. Each year in this country, more than 14,000 women 40 years old and younger are diagnosed with breast cancer, says Boston oncologist Ann Partridge, M.D., of the Dana-Farber Cancer Institute.

That's a lot of young women. That's a lot of breast cancer. And yet, mammograms still are not recommended for women under the age of 40.

I know just how Jon Lester feels as he survives the cancer that took him out of the game of baseball and threw him into the arms of the medical system.

It's not the baseball I can identify with. It's the little bit of cancer fear that never really goes away. And it's the will to return to the land of the living that Lester and I share.

"When you're laying in bed at night, when you're not doing anything, you think about it a little bit," he says. "As long as I keep busy, I'm all right. Every now and again I feel something and go, `OK, what was that?' but I try not to think about it too much."

Lately, Lester is thinking mostly about a return to Boston's pitching staff, less than six months after a cancer curve ball came right at him, threatening both his promising career and his life.

Lester, whose weight was down to 190 during chemotherapy, is back up to 212 -- five pounds less than his normal weight -- and his arms are powerful, his legs strong, his appearance healthy.

As a rookie last year, Lester became the first Red Sox left-hander to win his first five decisions. He was 7-2 with a 4.76 ERA when cancer came crashing into his world. Diagnosed with anaplastic large cell lymphoma in August, Lester received treatment at both the Dana Farber Cancer Institute in Boston and at his hometown Hutchinson Cancer Research Center in Seattle. His last chemotherapy dose was delivered on December 4. His last check-up was in January. And now, newly 23 and cancer-free, Lester is ready to play ball.

Lester is prepared for his coaching staff to hold him back. He says he can tell everyone until he's blue in the face that he's ready but he knows the staff has his best interests in mind. He trusts their professional opinions, and he'll accept a return to the minors if that's what is in store for him.

"I'm not as hard on myself as I was last year," he said. "It's just a matter of enjoying playing baseball and not necessarily the result. So (I'm) just trying to enjoy things and take it day by day and live my life the best I can."

International pharmaceutical company AstraZeneca is donating $10 million to the American Cancer Society (ACS). The donation is one of the largest gifts ever received by the ACS and will help provide support for patients in United States hospitals.

Support will come in the form of specially-trained ACS employees who will work in 60 different hospitals and cancer centers and will offer social, emotional, financial, and transportation assistance in medically underserved Atlanta areas.

London-based AstraZeneca, maker of breast cancer drug tamoxifen and other breast and prostate cancer drugs, made $26 billion in sales last year, the same year the company gave $7 million to a Boston Cancer Society for the development of a Hope Lodge.

I love a good cancer comeback story -- like the story of Phil Kessel and his courageous return to the NHL.

Kessel, 19-year-old Bruins forward and fifth overall draft pick for 2006, was diagnosed with testicular cancer last month. He underwent surgery and has been recovering off the ice until just recently -- when he was recalled to Boston from its farm team in Providence.

It's back to life and back to work for Kessel -- who is winning his match against cancer.

Kessel, a Wisconsin native, was the second Boston athlete this year diagnosed with cancer. Red Sox pitcher Jon Lester was diagnosed in August with lymphoma.

Women with ovulation disorders -- and related infertility problems -- have a lower risk of developing breast cancer, according to a study of more than 116,000 women.

Researchers from the Harvard School of Public Health in Boston studied data from the Nurses' Health Study II and evaluated female nurses aged 25 to 42, tracking them every two years beginning in 1989 and ending in 2001.

Results of the study, reported in the Archives of Internal Medicine, revealed 1,357 diagnosed cases of invasive breast cancer. Overall, women with ovulation disorders had a 25 percent less chance of developing this disease than those without the disorder.

Also detected was an even lower risk of breast cancer for women who experienced induced ovulation for treatment of infertility. This is potentially great news -- pending more research, of course -- for women worried about breast cancer implications of infertility treatment.

Sarita Zouvas knows what it's like to have a child in the hospital. Her daughter, Isabella -- who died while receiving treatment for cancer -- spent many days in the hospital, and Zouvas says it's hard to anticipate what items from home will make a child's stay more comfortable.

"We don't go prepared," she says. "You don't take clothes; you don't know what's going on. You get there and they put a gown on them. My first response is, 'I want to make them comfortable because they're scared.'"

Zouvas has found a way to bring comfort to the lives of children at her local Children's Hospital. And her goal is to make sure every child admitted to the hospital during the holiday season gets a complimentary pair of pajamas.

After the death of her daughter, Zouvas became involved with the Friends of Scott Foundation (FSF) -- a non-profit organization founded in memory of Scott Delgadillo who lost his life to childhood cancer. FSF strives to help children with cancer and their families with emotional and financial support in order to cope with this devastating disease. Zouvas became a part of the FSF support team and is thrilled she can help bring comfy jammies to sick children.

Zouvas says the response to her call for help has been overwhelming. Most pajamas are donated and have come from as far away as Boston. Employees of the San Diego Padres, Southwest Airlines, and the district attorney's office have also helped Zouvas in the endeavor she hopes will continue year-round.

For more information on the Friends of Scott Foundation and Zouvas' pajama drive, click here.

Ho, ho, ho! Santa Claus arrives early and he is seriously underdressed for the season.

It's not the image of jolly St. Nick remembered from childhood, but it does reflect the spirit of generosity and giving. On December 16th, the sixth annual Santa Speedo Run, which started when a couple of guys thought it might be fun to spread a little holiday cheer and raise money for breast cancer charity, was held in Boston, Massachusetts.

Runners in little speedos, mostly red in keeping with Santa's signature color, donning Santa hats and white Santa Claus beards, benefited Ellie's Fund Care for the Caregiver program. The Ellie's Fund offers free support services, like daycare and meals, for local women undergoing breast cancer treatment. The Santa Speedo Run participants solicit sponsorships from coworkers, friends and family with 100 percent of the donations going to The Ellie Fund. For more holiday cheer, visit the Santa Speedo Run website here.

Bruins rookie Phil Kessel is surviving testicular cancer. And the 19-year-old former University of Minnesota player, drafted in the first round this year, is talking about his shocking diagnosis and the surgery from which he is currently recovering.

Kessel, who is expected to rest for two weeks before returning to the ice, found a lump in his testicle and went immediately to his team internist, Dr. David Judge. Judge examined him, referred him for an ultrasound, and learned with Kessel that the lump was in fact cancer -- embryonal testicular cancer.

Both Judge and Kessel are happy to report that the cancer was localized to the right testicle -- which was removed during surgery -- and had not spread. Kessel, therefore, has a very low liklihood of recurrence.

Kessel, who has five goals and four assists in 27 games this season, says about his diagnosis, "I couldn't believe it. It was tough. I had a hard time with it."

Kessel thinks cancer will help him gain perspective on life. And he plans to speak out about his experience so others may benefit.

"If you're not feeling well go get checked out and make sure you're all right," he says. Getting checked out is what saved him -- and he hopes others will follow suit.

Kessel is the second Boston athlete to be diagnosed with cancer this year. Red Sox left-hander Jon Lester was diagnosed with lymphoma in August. With chemotherapy behind him, he is currently cancer-free. And so is Kessel.

Americans are urged to know their family medical histories -- and to share them with their doctors.

Spearheaded by the U.S. surgeon general's office and other public and private agencies, this urging is critical -- because knowledge of family history can lead to more frequent and earlier screenings for particular cancers, to changes in diet and exercise to combat onset of heart disease and diabetes, to more formal genetic counseling and testing if warranted.

This Thanksgiving marked the third anniversary of Thanksgiving National Family History Day, a day the surgeon general's office has reserved for family discussion and documentation of medical histories.

"Family history itself is the first and best genetic test," says Sharon Terry, president of Genetic Alliance, a non-profit group in Washington, D.C.

Brigham and Women's Hospital in Boston has started a work-place initiative regarding medical family history. In the past year, about half of the 13,000 employees -- from physicians to file clerks -- have completed the computerized family history forms developed by the surgeon general's office.

Acting surgeon general Kenneth Moritsugu says, "knowing your family history can help you make better health choices. Much of what we do in American health care is treat chronic diseases, many of which involve choices over a lifetime."

If you haven't tried fishing, it is one of the most relaxing, and at the same time, exciting ways to spend a day. If I want to find a center of calm and peace in my life, fishing is a guaranteed remedy to the hustle and bustle of an often too-busy lifestyle. Water is soothing, and nature has a way of resetting your internal clock to a slower more natural rhythm.

National Baseball Hall of Famer Boston Red Sox Wade Boggs and television's Addictive Fishing host Captain Blair Wiggins first met through the Pediatric Cancer Foundation (PCF). On November 10-12, with other celebrities and fishermen, both will take part in the Ninth Annual Mercury Grand Slam Celebrity Fishing Tournament as part of Reel In The Cure to raise money for childhood cancers.

In the meantime, on September 3rd, you can catch Boggs on the Addictive Fishing show on the FOX Sports Net (FSN) channel as he attempts to reel in the biggest redfish off Florida's Space Coast. Maybe you have to be as big a fan of fishing as we are to truly appreciate the excitement of watching a show about fishing. It's not the same as fishing, but it comes close. According to the press release, Wiggins is credited with bringing outdoor sports programming to a whole new level with Addictive Fishing.

The Jimmy Fund upped it's total by $2.8 million this Saturday -- thanks to celebrities Donald Trump, Ben Affleck, Billy Ray Cyrus, Jon Cryer, and others who helped raise funds for this cancer-fighting charity through a Boston radio-telethon. Established in 1948 to support cancer research at the Dana-Farber Cancer Institute, The Jimmy Fund has been the primary charity for the Boston Red Sox since 1953 and has been the beneficiary of this same radio-telethon for five years now. Since 2002, the telethon has raised more than $5 million to support research and care for both children and adults. This year's goal was to raise $2.6 million. With generous donations, the goal was reached -- and exceeded.

Trump -- who threw out the first pitch at the Red Sox-Yankees doubleheader on Saturday -- donated $60,000 to the charity. His donation jumped this year's total ahead of last year's $2.3 million. Red Sox owner John Henry donated $30,000, and Yankees owner George Steinbrenner gave $10,000. Massachusetts Senators Edward Kennedy and John Kerry also sent in donations during the 18-hour fundraiser that aims to strike out cancer.

There is still time to register, volunteer or donate for the Avon Walk For Breast Cancer which will take place in several cities across the United States -- Los Angeles, New York, Charlotte, Washington DC, Boston, Chicago, Denver, and San Francisco. This weekend walk that extends over two days and 39 miles will take place as soon as September 2006 in Los Angeles and as late as July 2007 in Denver. This walk, designed to benefit medically underserved women and men -- allowing them treatment they otherwise would not receive -- also funds research teams as they continue their quest for a cure. With Prevention magazine as the national sponsor and other official sponsors such as Reebok, the Avon Walk For Breast Cancer has made quite a mark already. This year's Chicago walk raised a record-breaking $8.2 million and tracked the steps of more than 3,500 participants. There is no better proof than this -- in my opinion -- that walking can make quite a difference.

Kaycee Marie Macdonald, now 12 months old, was diagnosed with neuroblastoma in May. So far, Kaycee has had 2 operations, one because her kidneys were failing and another to implant a tube in her chest for chemotherapy drugs. Every three weeks, she undergoes three days of chemotherapy. Friday, July 7, was just another day at the Jimmy Fund Clinic for Kaycee and her mother Kerri Macdonald, as Kaycee would be getting chemotherapy.

But that day would be different. As Kerri said in a CBS4 Boston television interview, "It's nice when the adrenaline rush is because of something happy and not for fear." The adrenaline rush of happy had to do with a surprise visit from Sheryl Crow. In town to perform at Fenway Park with Dave Matthews that night, Crow stopped in to visit with children being treated for cancer at the clinic. There she met baby Kaycee, where both cuddled and spent a little time together. For Kaycee's mother, it is a bright moment that she can hang onto in memory for the continued dark journey of worry and concern.

Not only that, but Kaycee, by being featured on the evening news, has captured the hearts of a whole new large family of viewers who will keep her in their thoughts and prayers -- and perhaps help the family out with donations as they struggle to get the care Kaycee needs to survive her cancer. With the visit from Crow, Kerri has started blogging about Kaycee. Kaycee is such a sweet little girl. You can watch the CBS4 Boston television interview video here.

According to Medline Plus, neuroblastoma is a form of cancer that occurs in infants and young children. It is rarely found in children older than 10 years. The cells of this cancer usually resemble very primitive developing nerve cells found in an embryo or fetus. The term neuro indicates nerves, while blastoma refers to a cancer that affects immature or developing cells.