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Smoking causes lung cancer, so does family history

Smoking is the biggest risk factor for lung cancer -- and 90 percent of all lung cancer cases are related to smoking. But family history is a risk factor too and can nearly double the risk of developing the deadly disease.

A study published in the October issue of Chest found by studying a population of Japanese adults that people with a first-degree relative -- mother, father, or sibling -- who had lung cancer had a 95 percent higher risk of contracting the disease. Those who smoked had the greatest risk, but those who did not smoke were still at risk. And women were more at risk than men. The type of lung cancer most associated with family history is squamous cell carcinoma.

The results of this study do not yet translate into recommended guidelines for screening. But those with a family history of lung cancer should make their physicians aware of their history. And perhaps one day people with family history will be identified as high-risk for lung cancer and will be included in further studies. In the meantime, these individuals should avoid all contact with all inhaled and second-hand smoke and should protect their children from all forms of tobacco smoke.

The U.S. Centers for Disease Control and Prevention estimates that more than 180,000 cases of lung cancer are diagnosed each year. About 170,000 die from the disease every year. It's the second leading cause of death for men and the third leading cause of death for women.

Ovarian cancer survival better for women of healthy weight

Recent research indicates that obesity makes ovarian cancer deadlier and more likely to recur. According to physician and senior author of the study, Dr. Andrew J. Li of the Cedars-Sinai Medical Center, maintaining ideal body weight is important for many reasons. This is just one more reason to reduce obesity -- because obese women suffering from advanced ovarian cancer are more likely to die than women at healthy weights. They also suffer recurrences more quickly. On average, women in the study considered overweight or obese saw an average of 16 months before recurrence while those considered underweight or at a healthy weight saw 25 months.

Perhaps it's the secretion of adipose tissue that makes tumors less sensitive to chemotherapy. Li said there are ideas on the table -- and his team are looking into them. One fact they feel certain about is that obesity does not increase the chances of contracting ovarian cancer. It just shows the odds of survival are diminished once the disease has been contracted.

Lifestyle choices, screenings critical in cancer prevention

It seems like common sense to me -- that lifestyle choices can affect a person's risk for contracting cancer -- but apparently, many people are not aware of this. Or they are aware but are not heeding the advice that might just save them from this life-threatening disease. According to Carolyn "Bo" Aldige, president of the Cancer Research and Prevention Foundation, in Alexandria, Va., it's not undiscovered treatments and therapies that are key to fighting off cancer -- it's likely that the toll cancer takes can be reduced by lifestyle changes and routine screenings. Aldige reports that nearly half of all cancer deaths are preventable. And she urges us to consider these facts.
  • Smoking is the most preventable cause of death in the United States and causes nearly one in five deaths, killing about 438,000 Americans each year. Yet 45 million adults still smoke -- 23 percent of them men and 19 percent of them women.
  • Poor nutrition, inactivity, and obesity account for one in three of the 564,830 deaths from all cancers. Experts say that excess calories cause mutations that start genes traveling down pathways that cause cells to divide out of control -- and that's what cancer is. According to Aldige, if each person could magically acquire the perfect body mass index, there would be a whole lot less colorectal, breast, and prostate cancers.
  • It requires little time and not much discomfort for certain screenings that can detect cancer at an early enough stage that it can be successfully treated. There are already screenings for breast cancer, colon cancer, prostate cancer, testicular cancer, cervical cancer, and skin cancer. And soon, there may be a simple screening for lung cancer too.
  • A diet rich in nutrients and vitamin supplements helps maintain health and prevent cancer.
There are some highly effective defenses against cancer -- but they require some attention and effort on the part of each individual. Not everyone will make health-conscious choices -- some for reasons out of their control (lack of access to screenings, for example) and some for reasons I personally do not understand. But maybe that's because I have already had cancer and I know that I don't ever wish for it to return. So for that reason alone, I plan to adhere to the considerations listed above. It seems like common sense to me.

Cervical cancer vaccine available for college students

Right here in Gainesville, Florida -- at the University of Florida to be exact -- the vaccine for cervical cancer is now available for college students. This vaccine -- called Gardasil -- could prevent women from contracting the human papillomavirus (HPV) which can cause cervical cancer and genital warts. Almost 30 of the more than 100 different strains of HPV are sexually transmitted -- and sometime in their lives, 50 percent of sexually active men and women will contract genital HPV infection. Many will not know they have it and will spread it unknowingly to sexual partners. Protection can come in the form of Gardasil which is approved for use in women between the ages of 9 and 26.

Women who are not sexually active are the best candidates for this vaccine because it is clear that they have not yet been infected. The vaccine is not effective for women who already are infected with HPV. And those who don't know if they are infected can determine if they have HPV through a routine Pap smear. If they do not have HPV, the vaccine is indicated. Once the vaccine is indicated, it is delivered in three separate doses over a six-month period of time. Each dose costs $120 -- which may discourage students from this option.

About 9,700 women in the United States will develop cervical cancer in 2006 and this cancer will kill 3,700 of these women. This vaccine -- if received well by young women who can afford it -- should prove a breakthrough in cancer research and prevention.

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