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Posts with tag cycle

Marijuana halts lung cancer growth by half

More and more media reports are mentioning the potential merits of marijuana. The most recent headlines say the active ingredient in the drug cuts tumor growth in common lung cancers in half and greatly reduces the ability of the cancer to spread.

Researchers at Harvard University tested marijuana's main ingredient, delta-tetrahydrocannabinol or THC, in both lab and mouse studies and say their experiments are the first to show THC inhibits the growth of cancer.

Researchers are not certain why THC inhibits tumor growth, but it could be that the substance activates molecules that arrest the cell cycle. THC may also interfere with angiogenesis and vascularization, which promotes cancer growth.

There is a long way to go in the study of THC. Yet "the beauty of this study is that we are showing that a substance of abuse, if used prudently, may offer a new road to therapy against lung cancer," says Anju Preet, Ph.D., a researcher in the Division of Experimental Medicine.

Sunday Seven: Seven stops on extreme makeover tour

I've had my very own extreme makeover. And while it has nothing to do with cosmetic plastic surgery or an overhaul on my house, it's been an appearance-altering and life-changing event. I'll call it my Extreme Makeover: Cancer Edition.

Stop One

The first stop on my extreme makeover tour came compliments of a lumpectomy -- to remove one cancerous tumor in my breast along with four lymph nodes. I was left with two scars that travel underneath my armpit, a bit of scar tissue buried beneath the skin, and a tinge of numbness that comes and goes without warning.

Stop Two

My second stop brought me a port -- to save my veins and ease the infusion of chemotherapy -- which for more than a year allowed me to look a bit like an alien. A foreign object sewn under the skin of my collarbone popped up something like a tracking device that identified my whereabouts. Now surgically removed, my port has been discarded. A scar marks the one-time location of this wondrous apparatus.

Stop Three

The third facet of my makeover was quite extreme -- is still quite extreme. It happened like clockwork -- 13 days after my very first chemotherapy treatment -- and while I knew it would happen, the shock of total hair loss was not minimized in any way, shape, or form by predictability. And the shock of my new dark, curly hair with a sprinkling of gray -- that replaced my blond, straight hair -- amazes me every time I look in the mirror.

Stop Four

For four months, I lost my menstrual cycle to chemotherapy -- not such a bad deal except for the hot flashes that arrived for the same four-month period. When my cycles returned, they were unpredictable and much more intense than ever before. They are still problematic.

Stop Five

Surgery and radiation limited the range of motion in my left arm. Physical therapy helped some, and weight training helps too. But my arm is permanently affected by the attempts to save my life.

Stop Six

Just when I thought my makeover journey was coming to an end, my mind told me otherwise. Bouts of fogginess, forgetfulness, and just plain odd behavior marked the beginning of what researchers now call chemo brain. The plentiful drugs that cycled through my body for almost two years are playing tricks on my brain.

Stop Seven

And to cope with it all -- my scars, my hair, my confusing cycles, my tightened arm, and my chemo brain -- I made one last stop at the pharmacy for an anti-depressant. Prescribed so that I could become accustomed to my new life after cancer, my Zoloft keeps me calm and peaceful and happy. And one day, when I have adjusted to all that has changed in my world, I will wean myself off this potion.

I am not sure I would ever elect to alter my appearance -- although I am sometimes tempted by a tummy tuck to remove what two more-than-10-pound babies left with me.

Mostly, I think cancer has done enough to reshape and redesign my whole self. And while I didn't wish for any of my cancer changes, I think they help me define me. They tell a story -- of challenge and hardship and victory and survival. For as long as I am alive, for as long as my extreme makeover is visible, it will be clear that I have conquered something great and powerful. And that makes me proud.

Jane Tomlinson completes epic ride across America

I have the deepest admiration for terminal breast cancer survivor Jane Tomlinson. In fact, you could rightly say I am in awe of her. This summer, I followed her epic journey across the US, as she left from San Francisco to ride across this country on a bicycle. Cycling 4,200 miles for cancer charity, she intended to end her ride at Battery Park in New York City, and she has arrived.

Why does Jane inspire me? It is her spirit. In times of any challenge or crisis, we all need heroes. People who inspire by sheer determination and resilience of will. Someone to look to as a reminder to keep going as long as we can. Jane is one of my heroes.

Continue reading Jane Tomlinson completes epic ride across America

Pedalling Penguin Appeal: man and penguin cross Australia in epic ride

In celebration of his 50th birthday, fitness enthusiast Patrick Thompson and his over-sized inflatable penguin Percy start the epic journey to cycle across Australia to raise funds for child cancer research today.

His fundraiser was inspired by the loss of three friends to cancer. Thompson estimates it will take 80 days to finish the journey from Margaret River in WA to the Manning River at Taree in NSW. He hopes to raise more than $50,000 for the Children's Leukemia and Cancer Research Foundation.

According to if it's bloody easy, everybody would be doing it Thompson, he has been training most of his life for this unusual and challenging event. The Pedalling Penguin Appeal website has been launched where you can learn more about Thompson, Percy the Penguin, check his progress at Where is Patrick? and donate a few dollars to a worthy cause.

Family doctor blogs painful breast lumps breast cancer

Marjory, who is currently undergoing chemotherapy for breast cancer and her husband Gordon, a family physician, both blog Beating Breast Cancer. Marjory shares her perspective as a breast cancer patient and Gordon shares his knowledge as a doctor. I check in on Marjory and Gordon regularly, as Beating Breast Cancer is one of my favorite blogs in the cancer community.

In a recent post, Gordon admits to checking the blog's traffic report to see who is visiting and what they are searching for when they arrive at the Beating Breast Cancer blog. He noticed that a search for information on painful lumps in the breast is a topic frequently searched for -- and so he put together easy to understand information for readers interested in learning more about breast pain and painful breast lumps. Gordon is reassuring in letting women know most breast lumps do not turn out to be breast cancer (although he insists that a woman see her physician immediately should she find a lump in her breast) and he explains the causes of painful breast lumps. To learn more, visit Gordon's A Painful Breast Lump - Could It Be Breast Cancer?

Pink tampons for breast cancer

Has anyone else questioned the intent of businesses hitching their product wagon to the pink campaign for breast cancer? I am not picking on this business in particular, it's just the business news press release of the day announcing another company going pink for breast cancer charity. According to vendPINK, a division of the dittie company -- in announcing the launch of its new cause-related pink vending program -- states that the vendPINK program will be supporting women in and out of the bathroom. The company goes on to state that "VendPINK vends the fun, feminine and fabulous dittie tampons that inspires and supports women during that time of the month. While out of the bathroom, vendPINK is inspiring those women fighting breast cancer." Okay. They said it -- not me.

"Our vendPINK programs reflects dittie's commitment to creating a network of women dedicated to supporting one another," said Barbara Carey, dittie and vendPINK president and founder. "Everyone has been affected by breast cancer in one way or another. We are passionate about creating this support system and do not want anyone to ever feel they have to face breast cancer alone." 20 percent of the profits from the sale of this product are going to breast cancer charity. I like all companies who donate a portion of their profits to cancer charity. But there is a small part of me that is becoming cynically exhausted by the pink. Maybe it's just me. How do you feel about the pink?

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