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Posts with tag defects

Prenatal vitamins protect kids from cancer

Besides preventing birth defects in the brain and spine and other congenital abnormalities, the folic acid found in prenatal multivitamins has now been shown to prevent cancer in children whose mothers take the vitamins during pregnancy.

A new Canadian study, appearing online in the journal Clinical Pharmacology & Therapeutics, estimates prenatal multivitamin supplements can save hundreds of children each year in Canada -- where only 40 to 50 percent of women take prenatal vitamins -- from developing leukemia, brain tumors, or neuroblastoma. And the vitamins may prevent 900 cases of pediatric leukemia and more than 300 brain tumor cases annually in the United States.

It's not clear which vitamins or minerals, and in what amounts, could be protecting babies from cancer, but it's possible folic acid -- critical for cellular function -- may be acting alone.

One thing is certain, says lead investigator Dr. Gideon Koren -- this is one inexpensive way to prevent cancer.

Link between hard plastic and breast cancer debated

A chemical found in hard plastics -- such as CD cases, baby bottles, food-storage containers, and even electronics parts -- has been loosely linked to incidences of breast cancer. Popular opinion cautions that if we were not worried about this news yesterday, we should not be worried about it today -- because studies are preliminary and nothing is definitive at this point. But there are definitely two sides to the debate over how harmful these hard plastics may be.

The chemical in question -- a pseudo-estrogen called bisphenol-A (BPA) -- appears to be absorbed by breast tumor cells, according to a new study published in the August 28 issue of Chemistry & Biology. Previous studies have linked small exposures of BPA to prostate abnormalities in mice that suggest a link between the plastic chemical and human prostate cancer. Some studies even theorize that embryonic and fetal exposure might influence mental retardation and birth defects. And because this pseudo-estrogen is a synthetic material that in human cells can trigger estrogenic effects, breast cancer now comes up as a disease that may result from this questionable chemical.

Critics say that average levels of the chemical found in urine is infinitesimally small -- about one part per billion. Some say the results of this research come from in-vitro studies that one expert says can never fully explain human disease. Yet the real crux of the matter, according to another expert, is that we are surrounded by all sorts of chemicals that are pseudo-estrogenic -- not just BPA -- and it's the cumulative effects that we do need to worry about.

Thalidomide: drug of tragic consequence approved for cancer

During the late 1950s, Thalidomide was prescribed to pregnant women in many countries around the globe as an antiemetic to combat morning sickness. As it turns out, the drug, which had passed safety tests necessary to gain approval, was a nightmare of unimaginable proportion when it was discovered that babies born to mothers who took the drug suffered extreme birth deformities and missing limbs. Many of the babies did not survive the first year of life. If it were not for Frances Oldham Kelsey, a reviewer for the Food and Drug Administration, who refused to grant approval for a drug she knew was not safe, many babies in the United States would have suffered the same tragic fate. Thalidomide was pulled from the market when it became clear what was causing a sudden epidemic in birth deformities. The drug was later introduced in the treatment for leprosy.

Drug makers have found a new use for thalidomide, being marketed as Thalomid, in the approval for treatment of multiple myeloma -- a blood cancer. It sounds like everyone is being very cautious about this drug, and with good reason, given its history. According to reports, it will be strictly controlled to prevent pregnant women from access to the drug. Thalomid also will carry a black box warning about an increased risk of blood clots for multiple myeloma patients.

PITS: People investigating toxic sites

Janice R. England has been investigating dumpsites and landfills and cancer clusters for over twenty years. In 1984, she founded People Investigating Toxic Sites, P.I.T.S., to provide information on locations of open and closed dumpsites and landfills, contaminated groundwater, and to investigate illnesses related to contamination of the environment.

P.I.T.S. features an online resource of a state by state list of toxic waste, military ordinance and chemical warfare dumps. According to England, many of these sites are linked to contaminated groundwater, cancer clusters, birth defects and various health problems. She has provided a way for you to find out if you live, work, play or send your children to schools that are on or adjacent to these toxic sites. Visit P.I.T.S. to learn more.

Traveling back in cell division time

This is amazing. Oklahoma Medical Research Foundation researchers have found a way to do what was thought to be impossible -- reverse the process of cell division. "Until now no one has been able to make the cell cycle go backwards," states Gary J. Gorbsky, Ph.D., a scientist with the Oklahoma Medical Research Foundation. According to the researchers, they were able to successfully control a protein responsible for the division process, interrupt and reverse the event, and send duplicate chromosomes back to the center of the original cell. To me, this ranks right up there with someone announcing they have perfected time travel. The implication of possibility in being able to reverse the cellular process is mind-boggling. It's science -- and not fiction.

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