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Posts with tag developing

Breast cancer risk assessment tool

Do you want to know your risk for developing invasive breast cancer? If so, you can use an online interactive tool for measuring your five year risk and also your lifetime risk of developing the disease.

There are seven questions to answer to calculate your risk. It should not be used by women who already have had a breast cancer diagnosis. This tool has been used successfully in clinics for women with a strong family history of breast cancer.

Keep in mind that other factors also affect the risk of developing breast cancer that are not accounted for by the online tool. Women who do not get mammograms will have a lower chance of having their breast cancer detected.

Thought for the Day: Headed for melanoma

Oh no. I think I 'm headed for melanoma. At the very least, I seem to have a very high risk for developing the disease, thanks to my once-stubborn pursuit of a silly tan.

Think about this:

A review of seven different studies concludes that using a tanning bed under the age of 35 -- I'm so guilty -- can increase the risk of melanoma by 75 percent. Even those who have ever used indoor tanning were 15 percent more likely to develop the disease.

We're talking the deadliest form of skin cancer here. So deadly some experts are recommending strong measures to restrict the use of tanning beds by young people. Adults should be discouraged from tanning, some say, but access should be limited for those under the age of 18.

New Jersey already has regulations in place -- those under 14 are banned from tanning salons and anyone between 14 and 18 must have parental consent.


If I could turn back time, I would listen to my grandma. She told me the sun -- and tanning beds too -- were no good. But I was young. And I didn't care.

Now I'm older. And I care. But it may be too late. It seems this could be one lesson I learn the hard way.

Thought for the Day: Breast cancer risk less than you think

While sitting in the lobby of my hospital's MRI center on Friday -- time for the annual breast MRI -- I found myself a bit irritated by an appointment mix-up that kept me waiting much too long for a procedure that in and of itself is no real treat.

As I waited to bare my breasts and dangle them through square cut-outs on an MRI table, I flipped through a few ancient magazines -- why are lobby offerings so old? -- and as is usually the case when I read just about any publication, out jumped some cancer news.

So maybe the wait was worth it. Without it, I wouldn't have found this enlightening bit of information, this thought for today.

Now I warn you -- this item I am about to share comes from an October 2005 issue of Parenting magazine, so it's a bit outdated. But it still holds some truth. And if you remember nothing else from this message, I hope you'll take to heart this one lesson -- women tend to overestimate their chances of developing breast cancer.

Think about this:
  • 46%: What women estimate is their lifetime risk of getting breast cancer
  • 13%: Their actual risk

Cervical cancer vaccine discount pursued for poor nations

United States drug company Merck hopes to offer the cervical cancer vaccine Gardasil to developing countries at much lower prices -- within months, if possible.

Currently, the three-dose vaccine is not affordable in the developing world -- where 80 percent of cervical cancer deaths occur and 95 percent of females have never had a Pap test . And while the exact discounted price has not yet been determined, Merck professionals report they are committed to slashing the price of Gardasil for these women.

Merck also aims to help developing countries receive drugs sooner. Right now, there is a time lag of 15 to 20 years between the approval of drugs in the West and the time they reach these countries.

International health experts are pushing for rapid worldwide access to Gardasil, the vaccine that protects women against the sexually transmitted human papillomavirus (HPV) which causes most cases of the disease.

At this time, the vaccine is available in the United States and in 13 European Union countries.

Expressing all that is within me

I spend 10.5 hours every weekday on my own with some combination of my two little boys. My day starts each morning and extends through meals and playtime and laughs and tears and fights and struggles and snuggles -- but never a nap -- and even a part-time preschool job where one or two boys always tag along. Sometimes I try to write during the day while my boys are happy and occupied. Typically, I don't accomplish much. Interruptions are endless -- as they should be for a mostly stay-at-home mom who chooses to devote her daytime hours to raising children.

And so I go it alone until dinner time when my husband returns from work and selflessly takes over and sets me free. He cooks, serves, and cleans up dinner. He plays and entertains and wrestles and heads up bath and book time. And then he transports each boy on his back to their respective beds.

During my moments of freedom each evening, I lose myself in my thoughts -- and I begin to write. I love my mommy job -- and wouldn't trade it for any other full-time job -- but I also love being alone. And I love writing.

Helen Keller said, "I must have something besides husband and children, something I can devote myself to! I want to go on living even after my death! And therefore, I am grateful to God for giving me this gift, this possibility of developing myself, and of writing, of expressing all that is within me."

Writing -- mostly about cancer -- helps me develop my surviving self. It helps me express all that is within me. And maybe it's fitting that I don't get too much time to dwell on the disease that consumed me for two years. If I had to choose between two busy boys and a life busy with cancer, I'd take two boys in an instant. At the end of the day, a little bit of writing about a little of cancer suits me just fine.

Esophageal cancer linked to a diet heavy in carbohydrates

Carbohydrate consumption of Americans has increased over the years and so has the incidence of esophageal cancer. Esophageal adenocarcinoma rose from 2,500 cases per year back in 1973 to nearly 15,000 cases per year in 2001.

The study reported by Vijay S. Khiani M.D., of Case Western Reserve in Cleveland, was presented at the American College of Gastroenterology meeting. The investigators found an association between the rising incidence of esophageal cancer in the United States and the increase in U.S. per-capita carbohydrate consumption over the past three decades.

Although the data could not prove a causal link, Dr Khiani noted that a carbohydrate-heavy diet can lead to obesity, which in turn can lead to gastroesophageal reflux disease (GERD). This disease has been linked to a greater likelihood for developing Barrett's esophagus, a precursor to lower-esophageal cancer.

Dr. Khiani stressed that the study does not support total carbohydrate avoidance, a strategy promoted by some fad diets. The investigators concluded, "This ecological study provides evidence for the hypothesis that excess carbohydrate intake in the U.S. population may partially account for the increased trend of incidence rates of adenocarcinoma of the esophagus. It is possible that obesity resulting from excess carbohydrate intake many be an intermediate link".

Preventing prostate cancer before it starts

High grade Prostatic intraepithelial neoplasia (PIN) is the most significant risk factor for prostate cancer. PIN is strongly predictive of adenocarcinoma and if its identified in a biopsy specimen then it warrants repeat biopsies to check for cancer. This preinvasive cancer does not seem to have an impact on the levels of PSA scores.

All doctors can do now is the watch and wait method with those diagnosed with PIN. A preliminary study has shown that Toremifene can decrease the incidence of prostate cancer in men diagnosed with this precancerous condition.

A study was done with 514 men who had been diagnosed with PIN and had no evidence of prostate cancer. They were randomized to daily treatment with Toremifene or placebo for twelve months. The researchers concluded that 6.8% of every 100 men had their prostate cancer prevented with Toremifene.

Having a precancerous condition is very stressful. Its like the sword is just hanging over your head waiting to drop. This medication and its use with PIN to prevent prostate cancer is in its early stages but it is hopeful because at the current time there is no treatment for PIN available.

Sunday Seven: Seven questions predict breast cancer risk

Each month, about 22,000 women log on to the National Cancer Institute (NCI) web site and answer seven questions to determine their risk of developing invasive breast cancer. The Gail Model, named for the NCI's chief biostatistician, Mitchell H. Gail, generates a five-year risk and a lifetime risk for each woman who answers each of these seven questions.
  • Does the woman have a medical history of any breast cancer or of any ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS)? Note: This assessment tool cannot accurately predict risk for a woman who already has a medical history of breast cancer.
  • What is the woman's age? Note: This tool only calculates risk for women ages 35 and older.
  • What was the woman's age at the time of her first menstrual period?
  • What was the woman's age at the time of her first live birth of a child?
  • How many of the woman's first-degree relatives -- mother, sisters, daughters -- have had breast cancer?
  • Has the woman ever had a breast biopsy? How many breast biopsies has the woman had? Has the woman had at least one breast biopsy with atypical hyperplasia?
  • What is the woman's race/ethnicity?
A simple drop-down answer menu is provided for each question, and explanations for each question are available. Upon completion of the short survey, the Gail Model spits out a five-year breast cancer risk and a lifetime breast cancer risk with comparisons to the general population of women.

While this is only an assessment -- based on statistics that do not always take into account individual differences -- it is still a helpful tool. Because it's clear that women can minimize breast cancer risk with behavior changes and sometimes medication. And generating a personal rating on risk is a rating worth knowing. It's also worth knowing that this tool was designed for use by health professionals. If you are not a health professional, consider discussing your results with your doctor.

Overheated sperm link to childhood brain cancer

Children's Hospital of Philadelphia researchers surveyed the parents of 636 children -- parents of 318 children that had been diagnosed with brain tumors and parents of 318 children who were healthy. Based on the knowledge that heat damages sperm, they asked the parents to try to remember the frequency of exposure to excessive heat -- saunas, hot tubs and electric blankets -- in the three months leading up to the conception of their child. If the average age of children diagnosed with the two brain tumors the researchers were focused on, medulloblastoma and primitive neuroectodermal tumors, then the parents were being asked to remember back on average four to ten years.

According to the researchers report, heat exposure among the men in the three months before conception appeared to be linked to brain cancer risk among the children. The researchers do conclude by stating that the idea that paternal heat exposure before a child's conception and increased risk of these childhood brain cancers must be considered speculative until more proof is found.

The last statement made by the researchers might be the most significant. Now that I have told you what BBC News is reporting about this study, which I assume the researchers in some form released to the news media, let me say I believe you could fly a space shuttle through the speculative link between heat-damaged sperm and childhood brain tumors based on a survey. How good is your long-term memory in recalling daily life four to ten years ago? How many ways can a man's sperm become overheated?

I hope in the case of this study, the news will come with a substantial and cautionary warning that it might very well be a connection of dots that do not connect. I can think of nothing more additionally painful for a worried father who is facing his child's cancer diagnosis, than to have it even suggested that his overheated sperm might be the reason for his child's suffering -- when in fact it might have nothing at all to do with his child's brain tumor. The only known fact about childhood brain tumors is that researchers are looking into environmental and genetic factors for clues, and there is little concrete evidence as to what causes childhood brain tumors.

Study shows red meat associated with pancreatic cancer

I'm never quite sure about what foods I should eat and what foods I should not eat. Sometimes I hear that fish is healthy and recommended and then I hear that I should not eat fish at all due to concerns such as mercury levels. It seems that opinion on certain foods -- like fish and carbohydrates and dairy items -- sways and changes, which leaves me uncertain about how I might approach my diet in the best possible way. But opinion on red meat seems to be getting more and more consistent -- as more and more studies indicate that red meat is associated with a variety of health problems. And now red meat appears to raise the risk of developing pancreatic cancer, according to a Swedish report in the International Journal of Cancer.

More than 61,000 women were studied for possible effects of meat, fish, poultry, and egg consumption. After 17 years, 172 of these women were diagnosed with pancreatic cancer, and researches say it's because of the red meat. I suppose this could have been a coincidence -- and these women were destined for their diagnoses regardless of diet. But researchers conclude that long-term consumption of red meat is associated with an increased risk of pancreatic cancer -- one of the most deadly cancers that is seldom detected at an early, curable stage.

The good news from this study -- there does not seem to be a connection between pancreatic cancer and the consumption of fish and eggs. And the consumption of poultry may actually cut the risk of pancreatic cancer.

First cervical cancer vaccine approved

It is official. The first cervical cancer vaccine has been approved by the Food and Drug Administration, FDA. Merck's Gardasil cervical cancer vaccine is the first of several cancer vaccines expected to win approval this year. Gardasil, which targets human papillomavirus, HPV, will be given in three doses over six months. HPV is known to be responsible for the majority of cervical cancer cases.

The cervical cancer vaccine is not without its warnings though. In an earlier post, cervical cancer vaccine protects and promotes cancer, we noted a caution that research has shown the vaccine can actually raise the risk of cervical cancer if the woman is already infected with HPV at the time she receives the cervical cancer vaccine. So, it is not for every woman.

We also noted in an earlier post, cancer vaccine facing Christian Right opposition, there is strong objection to the cervical cancer vaccine based on religious convictions regarding sex and teenage girls. According to experts, girls in their early teens are the most likely to benefit from the cervical cancer vaccine. 

If canned tuna is a risky food -- what fish is safe to eat?

Consumer Reports has completed a review of the FDA testing on mercury levels found in canned tuna and issued new safety concerns. While the focus is on a clear alert for pregnant women and the damage mercury-contaminated tuna can cause to a developing fetus, mercury is also known to have an adverse effect on the immune system of adults. For anyone interested in cancer prevention, a healthy immune system is a vital first-line defense to keeping cancer from developing in the first place. Mercury, once consumed, can stay in the body for years.

Because of the new information provided by Consumer Reports regarding the dangers of canned tuna, and because fish is an excellent cancer prevention food, here is a list of fish that have shown consistently low-levels of mercury during testing and are safe to eat daily. Wild salmon and tilapia can be safely eaten every day. Flounder, sole, mullet, Atlantic mackerel and crab can be safely eaten once a week. In addition, Consumer Reports found fish-oil supplements to be a safe, reliable way to get omega-3 fatty acids. You can check state agencies and the Environmental Protection Agency advisories for contaminant levels of fish caught where you live here.

Can heartburn cause cancer?

Studies show that nighttime heartburn increases the risk of developing other serious conditions, including cancer of the esophagus. Day or night, chronic reflux can gradually damage the esophagus. It may lead to inflammation and scar tissue that narrows the esophagus. In some people, chronic heartburn can lead to Barrett's esophagus, changes in the cells that increase the risk of esophageal cancer. But nighttime heartburn tends to leave acid in the esophagus longer, and therefore may cause more damage than daytime heartburn.

Healing Heartburn written by Lawrence J. Cheskin, MD and Brian E. Lacy, MD of Johns Hopkins School of Medicine in Baltimore, MD discusses how acids from the stomach can cause serious damage to the esophagus if left untreated. It can also cause chronic insomnia and difficulty working through the pain.

Some common ways to help stop heartburn are not eating two or three hours before you go to bed; putting blocks under the top of the mattress to elevate the head 4 to 6 inches; chewing gum to increase saliva which coats the esophagus with natural bicarbonate; and avoiding foods that can lead to heartburn -- such as alcohol, chocolate, coffee, carbonated drinks, citrus fruits and juices, tomatoes, pepper, vinegar, catsup and mustard, and spicy or fatty foods.

As in most cases where natural remedies and diets will not take care of the situation, you should consult your doctor for a more complete check up and diagnosis.

Crisis of healthcare costs a global issue

The costs of medical care are skyrocketing. Governments are grappling with the rising costs in how to provide healthcare and cancer patients are struggling to get the care they need. Where is the unfolding national and global healthcare crisis headed and what will our healthcare look like in the future?

According to the World Bank, the healthcare gap between rich and poor countries remains steady and warns the trend is likely to continue without some type of fundamental change in how we care for people in less-prosperous countries. Jean-Louis Sarbib, vice president for the World Bank's division that produced the new report, is quoted as saying, "This inequity has tremendous consequences for the health of the world's poor." It is predicted that the world's population is expected to grow from 6 billion today to a projected 7.5 billion by 2020, with most of the growth expected to be in developing countries.

Continue reading Crisis of healthcare costs a global issue

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