There are four pages in the March 2007 Reader's Digest featuring amazing discoveries, devices, tests, and cures. And many of the snippets of information are -- yes -- somehow linked to cancer.

Think about this:

• A new ultrasound technique lets radiologists distinguish between malignant and benign breast lesions. Using elasticity imaging, researchers accurately identified harmless and cancerous lesions in almost all of the 80 cases studied. If results can be reproduced in a large trial, this technique could significantly reduce the number of breast biopsies required.

• Scientists seeking new treatment for diseases can use an online tool developed by researchers at MIT and Harvard. The Connectivity Map matches diseases with compatible drugs, based on the genetic profiles of both. So far, about 160 drugs and compounds are cataloged, and a few new uses for existing drugs have already been suggested. Eventually, all FDA-approved drugs will be included.

• For those who sometimes forget to take their pills, a new device -- that can be preloaded with up to 100 doses of medication -- could one day be implanted in the body and programmed to administer drugs via wireless signals. This device, successful in tests using dogs, was designed to deliver medicines that are less effective when taken orally.

Sometimes it seems cancer's grip is tightening. Other times, in the war against this pesky disease, it seems we are on the verge of something really great.

One in 18 men and women will be diagnosed with colorectal cancer during their lifetimes -- that translates into more than 150,000 people diagnosed and more than 52,000 colorectal cancer deaths each year, securing the disease as the second leading cause of cancer death in the United States.

Fortunately, mortality rates for this disease have been declining due to earlier screenings, awareness of symptoms, removal of polyps, and improved treatments through advances in research discoveries -- like today's genetic breakthroughs.

In a recent study, researchers identified a cell pathway critical in the development of colon cancer and also lung and stomach cancers.

STAT3 (signal transducer and activator of transcription 3) is the newest discovery and is a target regulated by PRPRT (receptor protein tyrosine phosphatase T), already identified to be mutated in these cancers.

"The role of protein tyrosine phosphatase in cancer is still an under-explored area," says Zhenghe John Wang, Ph.D., Assistant Professor, Department of Genetics at Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center.

"Our study shows that receptor protein tyrosine phosphatase T regulates an important signaling pathway that is critical in cancer development. This identification will allow new approaches to pharmacological designs and facilitate alternative approaches for cancer treatment."

This study, published in the Proceedings of the National Academy of Sciences (PNAS Online Edition Feb. 20-23, 2007), provides new hope for the development of drugs that will target this potentially deadly disease.

I like to read. I just don't find much time to do it -- with two kids, two jobs, an unpredictable exercise schedule, endless medical appointments, and all the other craziness that accompanies life. I would like to find more time for books -- books a bit more complex than the one I found time to read at bedtime tonight about a frog and a toad who spend their days flying kites and enjoying picnics together. I would like to read books that capture relationships and life experiences and a bit of mystery too.

The last book I read -- The Shop on Blossom Street -- is the kind of book I like. It is easy to read and captivating and inspiring and comforting. It is the kind of book I want to keep reading -- long after I have to put it down to tend to distractions. Perhaps it's the thread of cancer woven into the storyline of this book that kept me wanting more.

The Shop on Blossom Street -- by Debbie Macomber -- follows four women who are all seeking change in their lives. The lead character opens a yarn shop, years after a cancer diagnosis and with the intention of moving forward despite an uncertain future. She hosts knitting classes and forms relationships with three other women in search of brighter days.

Character Lydia Hoffman -- the cancer survivor -- overcomes obstacles and challenges and even another cancer scare. She finds friendship and love and all sorts of unexpected discoveries. She even graces the pages of a second book -- A Good Yarn -- that follows her continued life journeys.

I have the book A Good Yarn. It's on my bookshelf. And I can't wait to read it. I just can't find the time.