International pharmaceutical company AstraZeneca is donating $10 million to the American Cancer Society (ACS). The donation is one of the largest gifts ever received by the ACS and will help provide support for patients in United States hospitals.

Support will come in the form of specially-trained ACS employees who will work in 60 different hospitals and cancer centers and will offer social, emotional, financial, and transportation assistance in medically underserved Atlanta areas.

London-based AstraZeneca, maker of breast cancer drug tamoxifen and other breast and prostate cancer drugs, made $26 billion in sales last year, the same year the company gave $7 million to a Boston Cancer Society for the development of a Hope Lodge.

Glenn Close is the 2006 Entertainment Industry Foundation (EIF) ambassador to the Saks Fifth Avenue Key to the Cure campaign. Oscar de la Renta is the 2006 designer of the Key to the Cure t-shirt -- available now at Saks Fifth Avenue stores for the price of $35. For each t-shirt purchase, $31 will benefit EIF's Women's Cancer Research Fund. T-shirts are available on-line and in retails stores everywhere.

All Saks Fifth Avenue retail stores and Saks.com will contribute to Key to the Cure by donating 2 percent of all profits during October 12-15. Off Fifth stores will donate 1 percent of profits during the same time period to benefit local and national women's cancer charities.

Key to the Cure is a women's cancer initiative founded in partnership with EIF's Women's Cancer Research Fund. The program receives on-going support from Mercedes-Benz USA -- set to donate one million dollars to the cause. EIF is the entertainment industry's leading charitable organization and has shared hundreds of millions of dollars in support of critical issues facing our society. Like breast cancer.

Pink Pony is the catch phrase for Ralph Lauren's initiative in the fight against breast cancer. Not only does Ralph Lauren support the fight by donating 10 percent of the proceeds from Pink Pony products to charity, but he has his own charity -- The Pink Pony Fund for Cancer Care and Prevention.

The Pink Pony Fund is a worldwide philanthropic effort. In the United States alone, Pink Pony recipients include Women's Cancer Research Institute at Cedars-Sinai in Los Angeles, Memorial Sloan-Kettering Cancer Center and Breast Cancer Research Foundation in New York City, Prevención, Inc., and Nina Hyde Center, both in Washington, D.C.

One of the premiere services provided by the Ralph Lauren Center for Cancer Care and Prevention is the patient navigator -- a concept created by Dr. Harold Freeman, medical director of the Center. Navigators assist patients and family members with access to health-care services and help them move with ease through the medical system. Navigators help patients with communication barriers, financial concerns, insurance difficulties, emotional issues, and more.

There is more than meets the eye when it comes to the pink pony. It is not merely a fashion statement that happens to kick a few dollars toward breast cancer research. It is a statement of true compassion and concern and commitment. It is a symbol of one man's hard work over the past 15 years to make a difference in the lives of women everywhere.

Quick autopsies -- or rapid organ donation -- may steer scientists in the direction of better diagnosing and treating the most lethal of cancers. Some 33,700 Americans will be diagnosed with pancreatic cancer this year -- and 32,300 will die. There is no early detection test for this disease and early symptoms are vague and may be mistaken for health concerns like indigestion. By the time the classic symptoms -- jaundice and itching -- surface, the cancer has typically spread and patients have only months to live. Rapid autopsies have been used before -- for Alzheimer's and prostate cancer -- but this a first in the study of pancreatic cancer and it just may lead to the discovery of what makes this cancer so aggressive and so deadly.

I'm in the market for a new vacuum cleaner. Mine is 11 years old -- it was a wedding gift -- and although it still picks up the dirt and sand and grime that often litters my carpet as a result of two busy little boys, it's been through the ringer. Maybe that's because all I do is vacuum, or so my 5-year-old Joey thinks. He was asked in preschool one day to talk about his daddy's job and his mommy's job. He told his teachers that his daddy "plays the keyboard" which is true but while he meant a computer keyboard, his teachers conjured up the image of a musician and wanted to invite Joey's daddy to join the class for a jam session. And Joey said that his mommy "vacuums." Of all the things I do in a day -- as a mostly stay-at-home-mom -- Joey seems to think vacuuming sums me up. I think this justifies the purchase of a new vacuum cleaner.

There's a pink vacuum cleaner on the market, and I think it's just what I need. Made by Oreck Corporation -- a company that intends to offer the finest products for a cleaner, healthier home -- this vacuum also benefits the Susan G. Komen Breast Cancer Foundation by donating $50 for each consumer who tries for 30 days this special edition Clean for the Cure product. This hypo-allergenic vacuum weighs just eight pounds and comes with an eight-year guarantee and eight free annual tune-ups. And you can't beat the pink color and pink breast cancer ribbon displayed prominently on this product that can tidy up the messiest of messes while helping to power the fight against breast cancer. I'm sold.