When Dr. Jian-Wei Gu went to Mississippi to study the cardiovascular system and the process of blood vessel growth, he had no idea he'd make national headlines about his research into the world of cancer.

Gu, assistant professor of physiology and biophysics at the University of Mississippi Medical Center, says his discovery of the mechanism by which alcohol consumption causes tumor growth was purely accidental.

And extremely significant.

Scientists have known for a hundred years about the link between alcohol consumption and cancer. A study from Paris in 1910 showed that 80 percent of patients with cancer of the esophagus or gastric track were alcoholics. More recently, scientists have found correlations between alcohol consumption and cancer of the mouth, pharynx, larynx, esophagus, liver, large bowel, and even the breasts. Yet lab experiments have always failed to show the effects in animals that investigators knew to be true in humans.

Until now.

It seems past studies used too much alcohol -- in concentrations of 20 percent -- and the animals just wasted away while showing no tumor growth. But when Gu used concentrations of one percent -- about one to two drinks per day in humans -- to study blood vessel growth, he detected stimulated tumor growth in both chick embryos and mice. Thus, his cancer discovery was born.

Gu has further concluded that melanoma cancers in mice grew significantly faster and larger in the mice who consumed the equivalent of one or two alcoholic drinks a day than the mice receiving no alcohol.

Gu's findings, now confirmed by other scientists, are evidence of what many have long suspected -- alcohol, even in moderation, increases cancer risk.

President George Bush vetoed a bill that would have allowed surplus embryos from fertility clinics to be used in research. This decision will cause slowing of cures for several major diseases including cancer.

If politicians say they support stem cell research then it doesn't necessarily mean that they support embryonic stem cell research which is the one that holds the greatest promise for the most diseases.

It was five years ago that President Bush 'allowed' research on the 60 existing stem cell lines. It didn't sway his decision however that we now know that these lines are not going to help us with human diseases.

I would say more of what I think about President Bush's decision but then people might start going out and burning my music CD's.

Oh .. wait .. I don't have any music CD's!

Australian newspapers are reporting that a woman in Britain is pregnant with the first designer baby selected to prevent an inherited cancer. The mother-to-be, who has not been named, conceived after receiving treatment from Paul Serhal, of University College Hospital, London. In Britain, Dr. Serhal pioneered the use of this procedure to detect inherited cancers.

The Human Fertilization and Embryology Authority awarded him licenses to screen for retinoblastoma and a form of colon cancer. Using a genetic-screening technology that will prevent the mother from passing on a hereditary form of eye cancer to her children, doctors removed cells and tested them for the cancer gene, and only unaffected embryos were transferred to her womb. There is heated debate over the ethics of this practice. How do you feel about designer babies?

Related post: Disease-free designer babies embryo selection.

Several days ago, the American Society of Clinical Oncology issued new guidelines concerning the preservation of fertility during cancer treatments. Many treatments for cancer will lead to infertility if precautionary measures are not taken before treatment begins. The two methods of fertility preservation with the highest likelihood of success for cancer patients are embryo cryopreservation for women and sperm cryopreservation for men. Today, I came across a news story describing another option called ovarian transposition. In the article about dreams surviving cancer, surgeons made tiny incisions in Carrie Lintner's abdomen and gently pulled her ovaries behind her uterus, where they were held in place with a few stitches. The uterus shielded her ovaries from the damaging radiation beams from the treatment she received for her recurrent Hodgkin's lymphoma. The ovarian transposition procedure took 30 minutes and saved her ability to give birth. Ms. Lintner, who is now cancer-free, is the mother of a baby girl, Maia.

Of the many special issues facing young adults who receive a cancer diagnosis is the concern over fertility. Cancer, chemotherapy, and certain surgeries, can diminish or eliminate the possibility of conceiving a child later on in life. Both women and men can suffer temporary or permanent infertility. New guidelines set out by the American Society of Clinical Oncology hope to provide consistent and comprehensive recommendations for fertility and cancer.

• Discussion about infertility as a potential risk of cancer therapy should be initiated with patients of childbearing age as early as possible after diagnosis.
• Physicians should identify whether the patient is at risk for treatment-induced infertility and should discuss with the patient their concerns about infertility and interest in fertility preservation, as well as available treatment options, and the best time to undergo fertility preservation measures, before beginning cancer treatment.
• Patients interested and eligible for fertility preservation should be referred to reproductive specialists to facilitate decision-making and fertility treatment planning.

According to the experts, the two methods of fertility preservation with the highest likelihood of success in cancer patients are embryo cryopreservation for women and sperm cryopreservation for men. However, these procedures take time, and cancer patients considering these options need to do so as soon as possible after the cancer diagnosis.