Tom Keilty of San Dimas, California lost his wife Ruth to breast cancer in 2005, 12 years after she was first diagnosed with the disease. From the very first day cancer entered their lives until the very last day of Ruth's life, the Keilty family received hundreds of hand-written notes for Ruth, filled with encouragement and support.

The notes are still arriving, this time for Keilty and his three children. The notes help strengthen this family's faith and help them grieve. The Keiltys are grateful for the trail of mail that has come their way -- and they ask others to consider writing their own their own notes of hope.

It's simple.

Just drop by a local retailer and pick up a special edition PaperMate Pink Ribbon Pen and Pink Pearl City of Hope Eraser. For each item sold through December 31, 2008, PaperMate will make a donation -- up to $200,000 -- to City of Hope for breast cancer research, education, and treatment.

Then sit down and Write for Hope in honor of someone battling breast cancer. Not only will you warm someone's heart, you will also earn the chance to win a $500 donation made in your honor to City of Hope Cancer Center.

Click here to enter.

In the not-too-distant future, dermatologists will be able to diagnose skin cancer without ever cutting the skin.

Right now, doctors cut out all suspicious lesions in order to examine them, to determine if they are cancerous or not. But with the development of a new microscope, cells can be examined right on the body -- without cutting.

Moles matter, reported Matt Lauer on Thursday's TODAY show during an interview with a skin cancer expert. Moles are highly associated with melanoma, the deadliest form of skin cancer. So it is critical that each mole is investigated. With this new high resolution technology -- essentially a video biopsy -- a camera will allow doctors to view cells, zero in on the area of concern, and pinpoint the exact cells that make up a mole. If the cells are similar in shape and size and have equal distribution, the mole is normal. If the individual cells are irregular and have no uniform pattern, the mole is abnormal and probably cancerous.

While cutting for biopsy purposes will one day be a thing of the past, cutting will still be necessary if a mole is characterized by cancerous cells. If it's cancer, it must come out. But the video biopsy can be used to map the border and boundaries and will allow for precise removal of the mole.

This technology is still developing -- but one day, perhaps eight to 10 years from now -- doctors will be able to more consistently detect cancer without removal of skin. For now, they must take a piece of the mole and put it under a microscope.

There are definite warning signs of skin cancer. Any mole that is asymmetrical with irregular borders and varied, dark colors should be reported to a physician. Also, any mole that changes in color, shape, or size and is bigger than a pencil eraser is cause for concern.

I am an expert in the game of what-if. I guess it's because my recent what if this hard lump in my breast is cancer worry turned into Oh My God, it is cancer that I am so polished at this exercise in all things irrational. Sure, some worries will be fulfilled by reality but for the most part, things turn out okay. But still, I worry. When a bone hurt in my arm last year, I was sure it was bone cancer. It wasn't. When I felt a soft bump on the roof of my mouth, I whisked myself to the dentist for my mouth cancer diagnosis. It was just a little bit of inflammation, probably from a cold. A headache landed me in a tube for a scan of my head. It revealed nothing interesting, and ibuprofen fixed me right up. And lately, I am checking every mole, freckle, spot, speck, and discoloration that adorns my fair skin.

I asked about each of these what-if marks yesterday at my annual skin cancer screening. Surprise -- nothing is wrong with me. But all unfounded fears aside, there is some method to my madness about skin cancer because I have had several bad burns in my life, have spent too many hours in the sun in search of a tan, and have already had a few pre-cancerous spots removed from my skin. So I do plan to monitor my skin -- just maybe not every day -- for the ABCDs of melanoma. And you should too -- because melanoma is the deadliest of skin cancers, and it is known for spreading, which makes treatment essential. So consider these what-ifs when screening yourself for skin cancer.

What if a spot on my skin is Asymmetrical? This means that one half of the mark on your skin does not match the other half. See your dermatologist.

What if the Border of the spot is irregular? This means that the edges are ragged, notched, or blurred. See your dermatologist.

What if the Color of the spot is not uniform? This means that shades of tan, brown, and black are present. Dashes of red, white, and blue add to the mottled appearance. See your dermatologist.

What if the Diameter is more than 6 millimeters? This is about the size of a pencil eraser. Any growth of any mole should also be of concern. See your dermatologist.

It is estimated that 44,000 Americans will develop melanoma annually. Of these people, 7,300 will die. But the death rate is declining -- because patients are seeking help earlier. Perhaps the ABCDs of melanoma are helping. I hope they help you -- and me too.