"The normal response of prostate cells when male hormones are blocked is cell death," said George Kulik, assistant professor of cancer biology and senior researcher at Wake Forest University School of Medicine. "The cancer cells find a way to resist the treatment and we wanted to discover the mechanism."

Researchers have discovered the canny and shrewd way prostate cancer cells manage to defy death and become resistant to hormone treatment. The prostate cancer cells are using three separate pathways to send signals to cancer cells by inactivating a protein, BAD, meant to cause cell death.

If animal and human studies further prove what the researchers have discovered, new drug therapies could be developed to keep BAD active and doing its job in helping to destroy prostate cancer cells.

I was present for death only one time in my 36 years of life. I consider this both a bad and a good thing. It's bad because I did not want my grandmother to die -- and watching it happen made it so real, so vivid, so painful. I don't think I would have ever chosen to watch my grandma die -- to watch her slip from consciousness to coma, to observe her altered body once death arrived, to witness the movement of her body on a stretcher as it was wheeled out of the house from the bedroom I still see every time I visit my mom's house. But I think I am lucky really -- and this is the good part -- because I got to be with her during her final moments. I got to watch her body as it lay still, peaceful and calm and still breathing. I got to talk to her and although she could not respond, I believe she could hear my words. And it makes me happy to know my grandma may have known I was with just prior to her flight to heaven. And after her flight, I got to touch her cool hands. I got to feel the power of the passing of one life -- a long life -- and I got to feel the comfort of a death that was not ugly or painful or difficult. It was sad -- it's still sad -- that my grandma died three years ago. But what a privilege it was to be part of the day she left this world.

Susan DeWilde left this world in much the same way -- with loved ones by her side. She was a fighter and had conquered several rounds of breast cancer, a tumor in her spinal cord, uterine cancer, lymphatic cancer, and then leukemia, which took her life at the age of 53. I don't know this from Susan herself but from her friend, Christy Mack -- who helped her accept her death and guided her into her own final moments so that she could escape her pain and die peacefully. Christy writes about her beautiful friend and her empowering death in an article that appears in the August 2006 Oprah Magazine. Titled Friends to the End, Christy's story details how she soothed her friend, cradled her hand, and talked her through her last breaths. She helped her on her way during a time her friend feared most. Christy writes, "What she and I shared the night she died was a precious gift of friendship, emotionally profound and sacred in its perfection. It broke my heart. It strengthened my soul."

This I understand.

The tunnel was long. And dark. And winding. And foggy. And ominous. It seemed to last forever -- at the time -- and at moments, time seemed to stand still. I was not sure if I'd ever pass through it and be okay -- if I'd ever see the light at the end. But I did. I tunneled through it all -- somehow -- and I came out feeling more alive than ever before. Now, some time after my escape from the fog, I am already taking for granted the fact that I am breathing, that I am healthy, that I am living. And when my fitness trainer noticed yesterday that I do not get dizzy and lightheaded anymore during my workouts -- when I once had to sit down, breathe, collect my whereabouts -- I realized that some of my progress since exiting my breast cancer tunnel is already lost on me. And I don't want to lose sight of where I was and how far I've come. I want to remember it and measure it and never forget how alive I am at this very moment. So I have started to really think about how things have changed since I felt stuck in time, in a dark place. I am thinking about my times in a hospital bed when I was barely able to stand up, barely able to walk a few steps without feeling like I would collapse. Now I can hop out of bed at a moment's notice, half asleep in response to a demanding child screaming from his bed. I am thinking about my once challenging pre-cancer exercise routine and how a time came when my legs felt so heavy I could not even contemplate walking down my street. Yesterday, I completed an hour of weight training. Today I ran for 20 minutes. Tomorrow, I go back for more weight training. And I remember feeling incoherent, unable to conjure of meaningful thoughts or sentences. And now, despite some potential chemo brain forgetfulness, I am back on track.

I have only just touched the surface. There is so much more to reflect on. So I plan to think more about my travels so I can better appreciate how I arrived at the exact place where I am right now -- where it's light and clear, where time passes at normal speed, where I feel lucky to be alive.

I found Sark long ago -- about 10 years ago when I was working with college students on a campus in Virginia. Part of my job was supervising Resident Assistants -- students who live and work on the residence hall floors and are responsible for building community among residents -- advising them and counseling them and mentoring them and stepping in when conflict and trouble arises. It's a tough job -- being a peer and being in charge at the same time -- and Resident Assistants receive intensive training on how to best manage a floor of students possibly living away from home for the first time. I got to train these student leaders at times -- and Sark's books helped me motivate, inspire, and get to know these individuals. And over the years, as I assumed other jobs and roles and purposes, I found that Sark was still a great companion for me. And now I realize that what Sark has to offer really applies to anyone looking for a little inspiration, a little direction, a little creativity, a little delight.