When Dr. Jian-Wei Gu went to Mississippi to study the cardiovascular system and the process of blood vessel growth, he had no idea he'd make national headlines about his research into the world of cancer.

Gu, assistant professor of physiology and biophysics at the University of Mississippi Medical Center, says his discovery of the mechanism by which alcohol consumption causes tumor growth was purely accidental.

And extremely significant.

Scientists have known for a hundred years about the link between alcohol consumption and cancer. A study from Paris in 1910 showed that 80 percent of patients with cancer of the esophagus or gastric track were alcoholics. More recently, scientists have found correlations between alcohol consumption and cancer of the mouth, pharynx, larynx, esophagus, liver, large bowel, and even the breasts. Yet lab experiments have always failed to show the effects in animals that investigators knew to be true in humans.

Until now.

It seems past studies used too much alcohol -- in concentrations of 20 percent -- and the animals just wasted away while showing no tumor growth. But when Gu used concentrations of one percent -- about one to two drinks per day in humans -- to study blood vessel growth, he detected stimulated tumor growth in both chick embryos and mice. Thus, his cancer discovery was born.

Gu has further concluded that melanoma cancers in mice grew significantly faster and larger in the mice who consumed the equivalent of one or two alcoholic drinks a day than the mice receiving no alcohol.

Gu's findings, now confirmed by other scientists, are evidence of what many have long suspected -- alcohol, even in moderation, increases cancer risk.

The old saying an aspirin a day keeps the doctor away seems to apply for certain cancers now. Researchers reported that aspirin and other NSAIDs decrease the risk of progression of the most aggressive form of Barrett's esophagus to esophageal cancer. In a study NSAID users took the drug at least once a week for six or more months any time during follow-up, regardless of daily frequency, duration, or type, the researchers reported. Galipeau and colleagues also found that those with three or more of the biomarkers who used aspirin or other NSAIDs had a 30% risk of esophageal cancer after 10 years, while those with the same biomarkers who did not use NSAIDs had a 79% risk of developing cancer within a decade.

The vast majority of patients in this cohort had gastroesophageal reflux disease and were undergoing therapy, mainly with proton-pump inhibitors. It is unclear how the frequency or severity of symptoms may have affected NSAID use by participants, the researchers said. However, to their knowledge, they said, symptoms from reflux are not associated with intermediate endpoints or cancer in Barrett's esophagus, so it is unlikely that symptoms could explain the association of NSAID use with reduced risk of esophageal cancer. The findings may help identify patients who may benefit most from a very cost-effective, noninvasive therapy in the form of aspirin or NSAIDS.

The U.S. government's Institute of Medicine reported that asbestos, which is accepted as a cause of a number of respiratory ailments including lung cancer, may also be a source for laryngeal cancer. The larynx produces the sound of your voice. Each year in the United States, more than 10,000 people learn they have larynx cancer. Men are four times more likely than women to get cancer of the larynx. Occupational related issues are certainly a factor with mechanics, construction, and other jobs that handle asbestos.

A series of studies have found that certain cancers of the throat and lungs are similar, so the U.S. Senate asked the institute to investigate a potential link between asbestos and other upper-body cancers. Asbestos is also linked to mesothelioma which is a rare cancer that attacks the lining of the chest.

Smokers and smokers that drink alcohol are even more at risk to develop cancer of the larynx. Symptoms of larynx cancer are hoarseness or other voice changes,lump in the neck, a sore throat or feeling that something is stuck in your throat, a cough that does not go away, breathing problems, bad breath, earaches, and weight loss.

Katherine Schaefer was investigating methods for treating the inflammation seen in Crohn's disease and ulcerative colitis when something terrible happened -- she noticed her carefully cultured cells were dead. And then something wonderful happened -- she realized she had stumbled upon a potential new method of attacking cancerous tumors that have become resistant to existing drugs.

Schaefer and her colleagues at the University of Rochester Medical Center in New York were testing a compound called a PPAR-gamma modulator -- a compound never considered a cancer drug, or a drug of any kind really -- when Schaefer made a calculation error and used a lot more of the compound than she should have. And her cells died.

Upon further study, Schaefer found the compound killed just about every possible epithelial tumor cell. These cells line organs such as the colon and also the skin. The compound, that works like taxane drugs but without eventual tumor resistance, also killed colon tumors in mice without making them sick.

The research team, whose findings are published in the journal International Cancer Research, plans more safety tests in mice. And eventually, if their outcomes are promising, they plan to design something they can patent as a new drug -- because they would love to see this disastrous lab experiment one day lead to treatment for cancers of the colon, esophagus, liver, and skin.

Cancer of the esophagus is one of the fastest rising cancers in the United States -- but the common screening test, both expensive and risky, is not widely used. Thankfully, a newer option, around since the mid-90s, is quicker and easier and is catching on around the country.

Trans-Nasal Esophagoscopy (TNE) is the better option, and it works like this: a doctor numbs the nose, inserts a thin, flexible tube -- no bigger than a pencil -- through the nostril and into the esophagus, removes a bit of tissue for biopsy purposes, takes a few pictures, and pulls the tube back out through the nostril. The patient gets to watch it all on a monitor and gets to depart from the procedure with no ill effects.

Traditional esophagus cancer screening involves a similar tube that is inserted through the mouth. Due to the gag reflex, patients are sedated. While there are often no complications from the procedure itself, the intravenous sedation can cause problems.

"You don't need those risks to see what's going on," says one doctor, who reports that esophageal cancer responds very well when caught early by tools like TNE.

In previous studies there has not shown to be an increase in survival when adding chemotherapy after surgery for gastric cancer compared with surgery alone. Most U.S. patients that are diagnosed with cancer of the stomach or lower esophagus have locally advanced disease that is hard to cure.

The MAGIC trial represents a landmark study in gastric cancer, as it is the first trial to demonstrate a survival benefit for pre- and postoperative chemotherapy. Researchers studied 503 patients with cancer of the stomach, esphagogastric junction or lower esophagus. One arm of the trial received three preoperative and three postoperative cycles of chemotherapy, the other arm of the study had only surgery.

The trial concluded that the chemotherapy group had smaller resectable tumors with negative margins, fewer patients had advanced nodal disease and the five year survival rate increased by 13 percent. It was noted that this is a significant advance for the treatment of this disease.

Carbohydrate consumption of Americans has increased over the years and so has the incidence of esophageal cancer. Esophageal adenocarcinoma rose from 2,500 cases per year back in 1973 to nearly 15,000 cases per year in 2001.

The study reported by Vijay S. Khiani M.D., of Case Western Reserve in Cleveland, was presented at the American College of Gastroenterology meeting. The investigators found an association between the rising incidence of esophageal cancer in the United States and the increase in U.S. per-capita carbohydrate consumption over the past three decades.

Although the data could not prove a causal link, Dr Khiani noted that a carbohydrate-heavy diet can lead to obesity, which in turn can lead to gastroesophageal reflux disease (GERD). This disease has been linked to a greater likelihood for developing Barrett's esophagus, a precursor to lower-esophageal cancer.

Dr. Khiani stressed that the study does not support total carbohydrate avoidance, a strategy promoted by some fad diets. The investigators concluded, "This ecological study provides evidence for the hypothesis that excess carbohydrate intake in the U.S. population may partially account for the increased trend of incidence rates of adenocarcinoma of the esophagus. It is possible that obesity resulting from excess carbohydrate intake many be an intermediate link".

I have a new friend who is a new breast cancer survivor. She is surviving a new diagnosis, a recent lumpectomy, and the moments leading up to another surgery to further investigate the margins surrounding the tumor removed from her breast. She is surviving the first phase of her breast cancer journey. A phase full of uncertainty and fear and panic. A phase so new and so fresh and so raw, her mind is whirling. A phase that has her grasping for any bit of direction she can find as she navigates a terrifying, unfamiliar road.

My friend is a young wife and mother whose worries are consuming her. She e-mailed me today and asked if I ever have moments when I look at my young children and worry that cancer will take me from them while they are young. She asked if I have always been so sure I will be okay. And so I replied with this candid cancer confession.

I didn't know what was coming when I plopped myself down in the waiting room of an Ear, Nose, and Throat clinic yesterday -- which is a good thing. Had I known what doctors would do to me, I may have run the other way. I may have learned to live with the pain I was experiencing each time I swallowed food. But I waited patiently, aware that doctors would "scope" my esophagus, mildly certain the procedure could be uncomfortable, completely unprepared for the full "scope" experience.

I swallowed a pill on Friday night -- not even a whole pill, just a half of one pill -- and it hurt when it went down my throat. I've had the feeling before, a sensation like the pill got stuck, but the discomfort has always gone away within a few hours. This time, it lasted. It hurt to swallow saliva. It hurt to swallow food. It just hurt. So after three days, I took myself to the clinic -- with the subtle worry that cancer was settling in my esophagus.

I know rationally that every ache and pain I experience is not cancer. But I've had cancer. And so I constantly battle a nagging fear lodged deep in my head that reminds me cancer is always a possibility, that cancer is often a shocking outcome of a routine little test for a simple little health concern.

I do not have cancer. I do not have cancer of the throat, voice box, esophagus, or stomach. That's the good news. The scope revealed -- via a tiny camera that traveled through my body -- nothing but healthy tissue. That makes me happy. The test did not make me happy.

I now know the scope is a long, thin tube that enters the body through one nostril. Ouch. It travels into the throat. Ouch. The patient swallows when it reaches the throat to assist in maneuvering it down further. Ouch. The scope then makes its way past the voice box, though the esophagus, and into the stomach. Ouch. Ouch. Ouch. The travels are all displayed on a monitor, and I actually got a glimpse of these body parts -- during the split second when I was able to control my gagging, loosen my grip on the arms of the exam chair, and open my clinched eyes. So I saw for myself that everything looks healthy -- just before the tube was pulled right back through all these parts, leaving me with a very sore throat.

Now that I am home and have talked with a few people, I hear that some patients are unconscious for this procedure. They are completely unaware of the horrors of the scope. I got a few sprays to numb my nose and throat and drank a thick cocktail of lidocaine -- but I did not get the luxury of unconsciousness. And in the end that is okay. I got to see what was happening. I got to hear the doctor's revelation that nothing major is wrong. I got to witness the wonder of medical technology. I got to prove to myself that I can handle a little discomfort in exchange for a clean bill of health. And I got to learn that I have a bit of acid reflux. And now I have to squash that nagging fear that reminds me of the literature out there suggesting a link between acid reflux and cancer.

Studies exist that link acid-reflux conditions to cancer of the larynx -- or voice box -- but authors of a new study say they all suffer shortcomings in methodology.

The new study, published in the American Journal of Medicine, was intended to make up for these shortcomings by comparing 96 men and women with laryngeal cancer to a group of adults without the disease. All participants were matched by age, gender, and ethnicity -- three of the most important risk factors for this cancer. Overall, the study found people with GERD -- gastroesophageal reflux disease -- were twice as likely to develop laryngeal cancer, compared to those without the condition. GERD has long been considered a possible risk factor for this cancer, mostly because GERD is common among people with the cancer. More definitive studies are on the horizon.

GERD, which occurs when the muscle of the bottom of the esophagus fails to close properly, allowing stomach acids to leak into the esophagus, is also linked to esophageal cancer.

Heartburn has never really been considered a major health concern. It has been considered uncomfortable and annoying and troublesome -- yet still only a harmless nuisance. In recent studies, though -- summed up in the September 2006 Oprah magazine -- heartburn has been linked to a deadly form of esophageal cancer. Apparently, people who experience heartburn one time per week or more have a fivefold or greater risk of adenocarcinoma of the esophagus -- a cancer with incidences jumping as much as 500 percent over the past 40 years. Experts insist, however, that adenocarcinoma is still rare. One doctor states that 40 percent of Americans have heartburn once per month -- yet only 8,000 to 9,000 people develop this specific cancer each year.

For the unfortunate few who do go on to contract cancer, there is hope in a surgical procedure to remove the cancer and part or all of the esophagus and nearby lymph nodes -- which can dramatically increase the odds for survival. For most of us, a bit of heartburn does not signal an eventual cancer diagnosis. It just means we might need to self-treat the symptoms with over-the-counter remedies. And a recent review at Stanford suggests that sleeping with your head elevated can reduce reflux pain.

You should see a doctor if your heartburn results in a consistent burning sensation, difficulty swallowing, or vomiting.

The addition of further chemotherapy added to neoadjuvant chemotherapy in patients with esophageal cancer can improve survival. When diagnosed with esophageal cancer the patient is usually given chemotherapy to shrink the tumor before surgery, it also may be accompanied by radiation. This gives a better chance that the tumor will be smaller and can be fully removed. It also is treating the body immediately with systematic therapy in case any cancer cells are circulating in the body.

The journal Cancer has published an article from researchers at MD Anderson Cancer Center regarding additional chemotherapy added to the neoadjuvant chemotherapy already given to patients who have locally advanced esophageal cancer.

The study included 130 patients with esophageal cancer who received neoadjuvant chemotherapy plus radiation therapy and their outcomes were compared to 117 patients who received the same treatment plus and additional course of chemotherapy (induction chemotherapy) prior to surgery.

At five years overall survival was 43 percent for those treated with the additional induction chemotherapy before surgery, compared to 28 percent for those not treated with induction chemotherapy.

The researchers concluded that the induction chemotherapy added to the neoadjuvant chemotherapy improved survival.

To cut down on cancer risks if consuming alcohol, The American Cancer Society, recommends cutting down drinks to one daily for women and two daily for men. Alcohol consumption on a daily basis increases the risk of cancers of the mouth, esophagus, pharynx, larynx, and liver in both women and men and also increases the risk of breast cancer in women. The risk elevates after one daily drink for women and two for men.

Oral cancers are six times more common in alcohol users than non alcohol users. About 75 percent to 80 percent of all patients with oral cancer consume alcohol frequently. Smokers who also drink are at much higher risks. Heavy alcohol use is the primary cause of liver cancer. Alcohol alters the liver's ability to metabolize some carcinogenic substances into harmless compounds or to disable certain existing carcinogens. Studies also show a relation between higher risks in breast cancer with alcohol use and the increase risk factor rising with the more drinks consumed daily. Alcohol increases hormones in your body.

Teach your children the importance of eating healthy and staying away from preserved meats. Yes it is quick and easy to prepare hotdogs or to order pepperoni pizzas when in a pinch for time or you are just too tired and don't feel like cooking a full meal. Parents should be the mentors to their children and set a healthy lifestyle starting with eating habits.

Most preserved meats contain nitrates which are converted into a carcinogen, cancer causing agent, in the body. This includes foods that are typically pink in color like bologna, salami, pepperoni, hotdogs, corned beef, pastrami, bacon, and cured ham.

Historically, nitrates served two purposes: to help prevent the growth of certain bacteria that can cause an outbreak of botulism, a deadly food-borne illness, and to give cured meat a pink color. These nitrates, once added to the meat, would break down over a period of time, forming nitrites. Eventually, nitrites themselves were added directly to the meat to speed up the curing process.

In cooked meats, the time and temperature of the cooking are the critical factors in preventing bacterial growth. In recent years, better production and food storage methods have decreased the potential for food-borne illness. However, nitrites continue to be used in cooked meats to maintain the traditional pink color and cured flavor. Nitrites can contribute to the formation of potentially dangerous carcinogens in the body, which in turn can result in malignant tumor growth over time.

Children are especially susceptible to nitrite poisoning. These carcinogenic compounds have been associated with cancer of the oral cavity, urinary bladder, esophagus, stomach and brain and child leukemia. One study found that children eating more than 12 hot dogs per month have nine times the normal risk of developing childhood leukemia. So take the time to help your children eat right and set good eating habits from the beginning. If you just have that uncontrollable craving for a hot dog, be sure to buy a brand of hot dogs that do not contain nitrates. Or when the pizza craving hits, order a veggie pizza and learn to leave off the pepperoni and ham and other processed meats with nitrates. Learning a healthy diet starting out will decrease the chances of childhood obesity, diabetes, and heart disease also.

It's summer time, it's hot, and most back yard cookouts have an ice cream maker churning away making that creamy frozen dessert that everyone loves.  Why not put a healthier more nutritional dessert on the table that even children will love? A diet high in fruits is likely to be linked to a decrease in the risk of cancer of the mouth, esophagus, stomach, lung, colon, rectum and possibly other cancers. Eating large amounts of fruits has been clearly linked to a decrease in the risk of cardiovascular disease. Eating fruits may also help improve bone health, diabetes control, and the maintenance of a healthy body weight. The consumption of fruits may strengthen the immune system, which is the body's defense against various diseases including cancer.

Three weeks ago one of my dalmatians developed a lot of bacteria in her stomach and my veterinarian reminded me of the healing powers of the cultures in yogurt.  She loves a couple of spoon fulls in her dry food. Tonight while I was on a fruit binge in the grocery store to fulfill my dedication of going back to my alkaline based diet, I remembered this salad recipe mixing the best of both worlds. I wasn't even tempted to pause at the frozen foods section to gaze longingly at my favorite mint chocolate chip ice cream.  By the way all of these ingredients are on the alkaline side of the food spectrum except for yogurt.  But your best diets contain 70 percent alkaline and 30 percent acid. So this salad is perfect.

Vicki's Mixed Fruit and Vanilla Yogurt Salad (with a minty twist)
1 cup blueberries
1 cup raspberries
1 cup diced strawberries
1 cup green grapes (slice them in half)
1 peach diced
1 pear diced
1 Granny Smith apple diced
1/3 cup sliced raw almonds
3 or 4 fresh mint leaves finely chopped.
1 6 ounce container vanilla yogurt

Mix everything but the mint in a large mixing bowl stirring gently so not to crush the raspberries and strawberries.  Sprinkle a pinch of the freshly chopped mint on the top of the individual servings.  It looks fancy and gives the dessert a little extra zing. This recipe serves 6 to 8 people. But remember if you have left overs to store them in an air tight container and then use them in the morning on your cereal or granola or for an added dessert treat at lunch.