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Posts with tag evista

Eli Lilly's Evista cancer drug approved by FDA

It's interesting when a drug is re-purposed into something aimed at fighting cancer, but that is what has happened to Evista, a prescription drug made by Eli Lilly which was originally for osteoporosis patients.

The FDA has officially approved Evista for use in breast cancer patients as of late this week, although the drug will now come with a box warning advising patients of a heightened risk for stroke by taking the drug.

I'm not sure -- are some drugs worth the possible benefits when certain side effects can be just as bad as what is trying to be treated?

FDA to consider Evista breast cancer drug approval?

Eli Lilly's Evista breast cancer drug has seen sharp criticism from womens' groups and more -- and has seen opposition from the FDA as well. The drug, nevertheless, may be approved by an FDA panel soon. What would most likely follow would be official FDA approval, which means the drug would then be free to be marketed and prescribed.

Although Evista was designed for osteoporosis prevention eight years ago, Eli Lilly now wants it used for breast cancer prevention in postmenopausal women. Is this a case of a drug being re-packaged to treat some other condition as a way to make it more "sale-able?"

Who knows. But when drugs meant for one condition are turned into drugs to treat something else, one has to question the motives. Will you?

Evista: breast cancer drug increases stroke risk

For over twenty years, the gold standard in long-term chemoprevention for women with estrogen-positive breast cancer was Tamoxifen. It seemed to work well in preventing recurrence of breast cancer for a certain percentage of women taking it for five years. Tamoxifen had its drawbacks though, as it was known to increase the risk for uterine cancer, blood clots and strokes. But there was nothing else that worked as well at preventing breast cancer from coming back, so women took it and hoped for the best.

A few months ago, researchers found that raloxifene, known by most as Evista, worked just as well as Tamoxifen with fewer of the potentially life-threatening side-effects of Tamoxifen. Seemed like good news at the time. But as I like to point out on a semi-regular basis, I feel there is a rush to swallow the latest newest pill before taking a long look at the potential dangers. Every pill comes with dangers. It is a matter of calculated risks when deciding to take a drug that might save your life only to cause a whole new set of medical problems.

And now Eli Lilly, Evista's drug maker, has come out with a new warning that its drug, previously thought to be safer than Tamoxifen, increases the risk for stroke. According to Eli Lilly, the finding was made during a study designed to see if raloxifene reduced the risk of heart disease and breast cancer in postmenopausal women who had heart disease or were considered at high risk.

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