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Lower insulin levels cut breast cancer recurrence

Researchers at the Dana-Farber Cancer Institute in Boston say exercise helps combat breast cancer. Not the first time we've heard this fact. But these same researchers have something new to say -- about the reason physical activity lowers the risk of breast cancer recurrence.

Jennifer Ligibel, MD, of Dana-Farber, reports that exercise lowers levels of the hormone insulin in the bloodstream. This is significant because there appears to be an association between relatively high levels of insulin, seen in obese and sedentary people, and an increased risk of breast cancer recurrence and breast cancer-related death.

"We know that women who are overweight at the time of breast cancer diagnosis have a higher risk of recurrence than lean women, but the reasons for this have not been clear," said Ligibel.

Continue reading Lower insulin levels cut breast cancer recurrence

Thought for the Day: Young women get breast cancer

OK, we all know young women get breast cancer. But the way some talk about the pair -- young women and the deadly disease -- it would seem finding a young one living with this type of cancer is like locating that needle in a haystack. Many a young woman -- like me -- have heard doctors and nurses and technicians and family and friends remark, "you are too young for the disease," and then dismiss cancer suspicions as needless worry.

The median age for women diagnosed with breast cancer is 65. But think about this fact, published in the Spring/Summer edition of Beyond: Live & Thrive After Breast Cancer.

More than 240,000 women in the United States age 40 and under are living with breast cancer. Each year in this country, more than 14,000 women 40 years old and younger are diagnosed with breast cancer, says Boston oncologist Ann Partridge, M.D., of the Dana-Farber Cancer Institute.

That's a lot of young women. That's a lot of breast cancer. And yet, mammograms still are not recommended for women under the age of 40.

Boston's Jon Lester hits cancer out of the ballpark

I know just how Jon Lester feels as he survives the cancer that took him out of the game of baseball and threw him into the arms of the medical system.

It's not the baseball I can identify with. It's the little bit of cancer fear that never really goes away. And it's the will to return to the land of the living that Lester and I share.

"When you're laying in bed at night, when you're not doing anything, you think about it a little bit," he says. "As long as I keep busy, I'm all right. Every now and again I feel something and go, `OK, what was that?' but I try not to think about it too much."

Lately, Lester is thinking mostly about a return to Boston's pitching staff, less than six months after a cancer curve ball came right at him, threatening both his promising career and his life.

Lester, whose weight was down to 190 during chemotherapy, is back up to 212 -- five pounds less than his normal weight -- and his arms are powerful, his legs strong, his appearance healthy.

As a rookie last year, Lester became the first Red Sox left-hander to win his first five decisions. He was 7-2 with a 4.76 ERA when cancer came crashing into his world. Diagnosed with anaplastic large cell lymphoma in August, Lester received treatment at both the Dana Farber Cancer Institute in Boston and at his hometown Hutchinson Cancer Research Center in Seattle. His last chemotherapy dose was delivered on December 4. His last check-up was in January. And now, newly 23 and cancer-free, Lester is ready to play ball.

Lester is prepared for his coaching staff to hold him back. He says he can tell everyone until he's blue in the face that he's ready but he knows the staff has his best interests in mind. He trusts their professional opinions, and he'll accept a return to the minors if that's what is in store for him.

"I'm not as hard on myself as I was last year," he said. "It's just a matter of enjoying playing baseball and not necessarily the result. So (I'm) just trying to enjoy things and take it day by day and live my life the best I can."

Share your Heart Fundraiser for Valentine's day

Peter Augustini's wife Jodi is fighting Stage IV breast cancer. They have three children, Charles, 10, Caroline, 7 and Max, 2.

Augustini is organizing a fundraiser to benefit the research Dana Farber Cancer Institute is using to help his wife fight breast cancer. He wanted to help Jodi and others fighting her type of aggressive breast cancer, referred to as Her-2 positive breast cancer.

Augustini decided to take on a holiday, Valentines day, that some people seem to think is a commercially contrived holiday. Augustini says "This is the chance to do something meaningful".

You can purchase a three inch wooden heart for your Valentine via the Share your Heart Fundraiser. The proceeds will benefit a fund specifically set up to fund research into a cure for Her-2 neu form of breast cancer. The research involves work on a drug called herceptin, which is attracted to specific proteins found only in cancer cells in the body.

The hearts are $5 each. You can also purchase a package of 10 for $20 and a package of 25 for $40. The hearts come unpainted and ready to decorate.

Share Your Heart Valentines are available for order vial the Dale, Wheelock and Memorial School Web sites, www.medfield.net or by e-mail to paugustini@cera.com.

Celebrities, Red Sox help raise money for The Jimmy Fund

The Jimmy Fund upped it's total by $2.8 million this Saturday -- thanks to celebrities Donald Trump, Ben Affleck, Billy Ray Cyrus, Jon Cryer, and others who helped raise funds for this cancer-fighting charity through a Boston radio-telethon. Established in 1948 to support cancer research at the Dana-Farber Cancer Institute, The Jimmy Fund has been the primary charity for the Boston Red Sox since 1953 and has been the beneficiary of this same radio-telethon for five years now. Since 2002, the telethon has raised more than $5 million to support research and care for both children and adults. This year's goal was to raise $2.6 million. With generous donations, the goal was reached -- and exceeded.

Trump -- who threw out the first pitch at the Red Sox-Yankees doubleheader on Saturday -- donated $60,000 to the charity. His donation jumped this year's total ahead of last year's $2.3 million. Red Sox owner John Henry donated $30,000, and Yankees owner George Steinbrenner gave $10,000. Massachusetts Senators Edward Kennedy and John Kerry also sent in donations during the 18-hour fundraiser that aims to strike out cancer.

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