Left-handed women under the age of 50 are more than twice as likely to develop breast cancer than those who are right-hand dominant.

What?

Yep, that's what a new study reveals.

This left-handed conclusion, published in the journal Epidemiology, comes from the study of 12,000 women in the Netherlands whose medical histories were followed for 13 years. Discounting all other factors -- lifestyle, environment, and other disease -- left-handers came up with a risk of breast cancer 1.39 times that of right-handers. For pre-menopausal women, the figure climbed to 2.41.

I just saw a powerful American Cancer Society (ACS) public service announcement in a magazine. A picture of a young woman fills most of the page and this woman, shown holding a framed photograph of another young woman, looks solemn. The words that accompany the photo capture the sadness in her eyes:

My sister accidentally killed herself.

These are the words that follow:

She died of skin cancer.

Most people think skin cancer happens to other people, according the ACS. Yet it's the most common of all cancers. And left undetected, skin cancer can be fatal. It is also curable -- if caught early.

It's been suspected that taking too many vitamins may spike men's risk of dying from prostate cancer. On Wednesday, the biggest study yet to link high-dose multivitamins and prostate damage was published in the Journal of the National Cancer Institute.

Government scientists have been looking at the diet and health of almost 300,000 men. One third reported taking a daily multivitamin. Five percent were heavy users, marked by use more than seven times per week. Within five years of the study's launch, 10,241 men had been diagnosed with prostate cancer. About 1,476 had an advanced form of the disease. And 179 died.

It seems heavy multivitamin users were nearly twice as likely to get fatal prostate cancer as men who never took the pills. Yet, oddly, researchers found no link between multivitamin use and early-stage prostate cancer. It could be that vitamins have little effect until a tumor appears -- and then it spurs growth.

More studies are on the horizon for this topic, which is becoming more and more pressing.

This comment just arrived in response to yesterday's post Headed for melanoma, and it's just too raw and powerful to leave buried in the comment section of the site.

So here it is, word for word -- a chilling and empowering message from a 37-year-old mom of two living with a disease that is downright deadly.

I have melanoma. I was diagnosed last August and have had 6 surgeries in 6 months.

I have lost 4 members in my melanoma support group. I go to Jaime's funeral tomorrow afternoon. She was 29 years old. Heather was 37 when she died on March 2, 2007. The midwife noticed a suspicious mole on her leg during the birth of her 4th child. She died 23 months later. Jan was a mother of 5 ages 9 to 19, she passed away on February 8, 2007. Ceri was only 20 years old when melanoma claimed her life on January 14, 2007.

I always thought skin cancer had to be HUGE, ugly, and hard to ignore. I didn't know it could be small, have no symptoms, and KILL you.

Melanoma incidence is increasing faster than any other cancer. According to statistics found on the American Cancer Society's website (www.cancer.org), the prognosis for someone diagnosed with melanoma is worse, stage for stage, than someone with breast cancer.

Getting more than 3 blistering sunburns during childhood doubles your risk. Sunbed use increases ones risk. Having fair skin and light eyes also puts you at a higher than average risk, but having dark skin does not make you immune. Bob Marley died from Melanoma in 1981.

Everyone at higher risk should get screened by a dermatologist every year. And all of us should be checking our own skin each month.

Melanoma is a virulent and aggressive cancer. It begins in the melanocytes, or the pigment in the skin. It presents itself as a change in an existing mole or skin pigment, or in the formation of a new one. It is easily treated in its most early stages. Once it spreads, though, it is often fatal.

Unfortunately, there is no cure for melanoma. Melanoma is one of the cancers that won't respond to conventional chemotherapy. There have been no significant advances in the medical treatment or survival rate in the last 30 years.

More awareness is needed. Most think "it's only skin cancer" and consider it nothing serious. But I can tell you with absolute certainty, they are DEAD wrong.

Dr. Len Lichtenfeld, MD, is the deputy chief medical officer for the American Cancer Society. He is also a blogger and authors his very own blog -- called Dr. Len's Cancer Blog.

Dr. Len writes on his blog about all sorts of topics related to cancer. He shares his opinion on the recent drop in breast cancer cases (December 15, 2006), he promotes the Great American Smokeout (November 14, 2006), he sounds off on lung cancer screenings (October 25, 2006), and he urges parents to always slather sunscreen on their children (October 5, 2006). He has so much more to say -- and his blog is a great stop for those wishing for more information on hot cancer topics.

As this year comes to a close, Dr. Len offers a review of what he believes were the hottest cancer topics of 2006.

Dr. Len reflects in his blog about decreased cancer death rates that represent real progress in the fight against cancer. He calls the HPV vaccine a breakthrough and he recaps the STAR trial -- a comparison of raloxifene to tamoxifen to reduce the risk of recurrent breast cancer in post-menopausal women -- with emphasis on how raloxifene proved just as effective as tamoxifen, but with a better safety profile. He calls new targeted therapies a dream -- with a hefty price tag -- sure to garner debate and discussion in 2007.

Dr. Len reviews the Surgeon General's report on second-hand smoke -- it's harmful to non-smokers, the report says -- and he marvels at the capability of science to approach an understanding of what makes a cancer cell a cancer cell. He also remarks on how remarkable it is that chronic myelogenous leukemia is in fact chronic and no longer fatal, thanks to the drug Gleevec.

Of course, there is ample attention given to the declining incidence of breast cancer, reportedly due to less women using hormone replacement therapy, and the risks weighing on those who are overweight and obese, and survivors and supporters who gathered for Celebration on the Hill -- the site of one incredible American Cancer Society event.

Dr. Len closes his review of 2006 with recognition of three celebrities who lost their lives this year to cancer -- Dana Reeve, Ann Richards, and Ed Bradley. And while he recognizes there are other lives and other stories that deserve mention, there is simply not enough time or space for him to do justice to every noteworthy item.

"What we have seen over the past year is an incredible leap forward in cancer research, diagnosis and treatment, and I suspect there are going to be even more exciting developments in the coming year," says Dr. Len who looks forward to 2007 -- a year that is sure to deliver more hope and more progress in the fight against cancer.

Over half of advanced-stage ovarian cancer patients who appear to be disease-free after initial treatment develop recurrent disease. A binding protein responsible for ovarian cancer recurrence has been discovered by John Hopkins researchers, leading to a greater insight into why some women experience a quick and sometimes fatal recurrence of ovarian cancer after initial treatment.

The NAC-1 protein was found in cancer tissue found of ovarian cancer patients who went on to experience recurrence within the same year. Researchers feel that this discovery, and testing for the binding protein, will allow oncologists to take treatment measures to block NAC-1 activity.

"Because recurrent cancers are often what really kill patients, and most ovarian cancer is diagnosed when it's already advanced, our findings offer women a better chance of catching or preventing recurrent disease early and increasing survival," stated Ie-Ming Shih, M.D., Ph.D., associate professor of pathology at Johns Hopkins Kimmel Cancer Center.

Roy Thayers has experienced death up close, as he was caregiver for his first wife as she battled cancer -- he knows what it is like to watch someone fight for their life -- and he was there when she lost her life to cancer.

Thayers, who at the age of 77 lives alone, was recently told by his doctors that he was at risk for a fatal heart attack and might lose his life if he didn't undergo heart surgery to unblock the heart valves immediately.

The problem of avoiding death and living longer became a matter of time and money. When the NHS put Thayers on a nine-month waiting list for heart surgery, he worried he might not have that long to wait -- considering the urgency with which the doctors had impressed upon him concerning the imminent threat of a fatal heart attack without surgery. He was told he could have the surgery immediately if he paid for it himself.

Welcome back from the weekend! Here is a review of what we were talking about during the second week in July in our other health blogs.

From The Cardio Blog:

• Bucindolol: experimental heart failure drug.
• Mammograms can find heart health problems.
• Eggs: bad or not bad for heart health -- which is it?
• The clock of life and time of day determines heart health.
• Extreme obesity raises mortality rate in women.
• Austrailian stem cell research innovates new heart treatment.
• Public physical activity program helps weight loss, lower blood pressure.
• Tuna imported from Latin America has highest mercury level.
• Eating less helps slow aging process.
• Teens helped to learn healthy diet habits with household food rules.
• Volunteer work helps seniors stay active and healthy.
• Working overtime worse for womens health.
• Aging and single living combined linked to higher heart disease risk.
• Tubby kids motivated to exercise by reward of TV time.
• Humidity and high temps linked to rise in summer heart attacks.
• Comedian Red Button dies of vascular disease.
• Migraine aura linked to increased heart attack stroke risk.
  

From The Diabetes Blog:

• Martial arts black belt uses youth group to fight diabetes.
• FDA approves GlaxoSmithKline diabetes drug.
• Pink Floyd Syd Barrett dies from diabetes complications.
• Update on fatal NC car crash involving diabetic driver.
• Major study links Type 2 diabetes and glaucoma risk.
• Life insurance industry plays catch-up.
• A1c Champions program trains diabetes mentors.
• Danish study confirms suspected diabetes, multiple sclerosis link.
• Debate continues on virtues, shortcomings of inhalable insulin, Exubera.
• Blogger's advice to T2 diabetics: follow in footsteps of movie producer Weinstein.
• Diabetes, obesity blamed for sky-high US kidney failure rates.
• Canadians await approval of inhalable insulin.
• Lifestyle ed could greatly reduce diabetes onset in older Americans, say researchers.

To your good health! To a great week!

Lung cancer affects more than 80,000 American women annually. More than 70,000 of these cases are fatal. Thirty thousand more women die from lung cancer than from breast cancer. And lung cancer claims more lives of more women than breast, uterine, and ovarian cancers combined. Yet a new study reveals that American women are uninformed about statistics like these -- and about the threats posed by lung cancer.

A 2006 survey of 500 women provides a snapshot of women's attitudes and beliefs about lung cancer -- and the overwhelming conclusion is that there is a widespread lack of awareness about the nation's top cancer killer. And here's the lowdown:

• Only 41 percent of women know that lung cancer is the leading cancer killer in the United States.
• Only 8 percent of women know that exposure to radon gas is the second leading cause of lung cancer -- 60 percent instead believe that second-hand smoke is the culprit.
• Only 36 percent of women know lung cancer kills more women than breast cancer.
• Only 41 percent of women know that one in 17 women will develop lung cancer sometime in her life.
• Only 4 percent of women know that women typically fare better than men following lung cancer treatment.
• And 25 percent of women mistakingly believe that there is a standard screening test to detect lung cancer in its early stages. Currently, there is not one.

Lung cancer is often believed to be a man's disease. But it is not. It affects tens of thousands of women too. And now I -- as one of the previously uninformed women -- know better.

One of the first books I read after my breast cancer diagnosis was issued in hardback in 1986 -- 20 years ago -- and then was published again and reissued and reprinted in 1990, 1998, and 2002.While the cover has changed and perhaps some wording too, the message in this book -- Love, Medicine, & Miracles by Bernie S. Siegel, M.D. -- remains unchanged.  And it is inside the covers of this book that I keep learning that I have the capacity and power to become an exceptional patient -- despite the fact that I've been faced with a life-shattering diagnosis of cancer.

Delaying treatments or surgeries to get second or third opinions or to make up your mind what is best for you, can really make a difference in surviving bladder cancer. However, sometimes postponing bladder cancer surgery might prove to be fatal. 

More than 61,000 people are expected to be diagnosed with bladder cancer in the United States in 2006. Although most cases are caught before the cancer has spread, about 20 percent of bladder cancers are diagnosed when they have already grown into or through the bladder wall. About half of patients with bladder cancer this advanced die within 5 years after surgery. Not delaying surgery is a simple thing doctors and patients can do to improve the chances a patient will survive.

Research found that delaying surgery more than 3 months led to a higher death rate. Three years after surgery, the death rate from bladder cancer was 51percent in patients who waited more than 3 months, compared to 38 percent in those who had surgery within 3 months.

In one study researchers found one reason for the delay was that the patients were getting second and third opinions to see if the surgery was really needed. Other studies found delays in surgery because patients had other medical problems. This might have caused the delay and perhaps made them less likely to have a good outcome. But in reviewing the charts, they found that other medical conditions were a problem in only 15 percent of patients who delayed surgery. Just 12 percent delayed treatment because they had trouble making a decision about it. Most of the delays -- 46 percent -- were caused by scheduling problems for tests as well as the surgery.