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Posts with tag fertility

Fertility may be preserved after ovarian cancer

Women with malignant ovarian germ cell tumors who undergo surgery intended to preserve fertility, in addition to platinum-based chemotherapy, are likely to maintain fertility, says a new study from MD Anderson Cancer Center in Houston. Malignant ovarian germ cell tumors occur in the eggs of the ovary and tend to affect young women.

71 out of the 132 patients in the study underwent the procedure and reported still having menstrual periods and 37 children had been born to 24 of the women after their cancer treatment. Compared to the controls, the cancer survivors had higher reproductive concerns, less sexual pleasure. However they scored higher in terms of relationships with significant others, either within marriage or outside of marriage.

Dr. David M. Gershenson said that only half the patients had the fertility-sparing surgery, which "is much too low and reflects the fact that many of the patients underwent primary surgery by non-subspecialists who performed unnecessary sterilizing surgery in many cases."


Eggs from young girls with cancer successfully matured

Chemotherapy is harsh, which is good when it comes to killing cancer. What's not-so-good is that it can also cause hair loss, inflict nausea, and disable the proper functioning of all sorts of organs -- including the ovaries. Chemotherapy, therefore, can affect female fertility.

In some cases, doctors have extracted immature eggs from adult women about to receive chemotherapy, matured them in a laboratory, and then implanted them when the women are ready to have children. Until now, no one had ever tried this with eggs from young girls -- girls who have not yet undergone puberty. But it's just recently happened.

Doctors have removed eggs from young female cancer patients and for the first time, have brought the eggs to maturity before freezing them.

Continue reading Eggs from young girls with cancer successfully matured

Fertility drug gives cancer patients hope

For young women diagnosed with cancer, the disease is more than life-altering, it also sometimes dashes all hopes and dreams they might have had for the perfect marriage, the perfect career and the perfect foray into motherhood. It might seem impossible to have children after cancer, since treatment often seriously compromises a woman's chance at conceiving, but all hope's not lost. For instance, Hodgkin's survivors can get pregnant, according to a study, and women who've undergone chemo can freeze their eggs for fertilization.

And now it's being shown that a drug developed in Australia can give new hope to wannabe mothers. It works by shielding the ovaries from harmful cancer treatments by temporarily shutting them down, so to speak. The drug's been impressing doctors around the world, and honestly, I can't wait to see it hit the market and offer some salvation for young women from the horror that is cancer.

Thought for the Day: I'm too young for this

There's this guy. His name is Matthew Zachary. He's a cancer survivor, a motivational speaker, a concert pianist, and the founder of a resource portal for young adults surviving cancer.

Steps for Living, Inc. -- also known as I'm too young for this -- was created by Zachary because he wants us all to know there are awesome cancer support services out there for adolescents and young adults. He means really awesome opportunities -- like spa retreats, online forums and blogs, social networking, camping excursions, fertility education, peer counseling, financial scholarships, and more.

You may be too young for cancer, but you are not alone, says Zachary whose mantra is Get Busy Living. And this is exactly what he is doing, despite challenges and setbacks in his own cancer recovery.

Think about this, an e-mail written by Zachary for those near and dear to his heart:

I am writing to share that I have suddenly gone deaf in my left ear. The condition is called Sudden Sensory Neural Hearing Loss.

After consulting with the country's best hearing experts as well as my oncologist, it has been determined that this is unequivocally a latent, long-term side effect of my post-operative cancer treatments from eleven years ago. Evidently, the excessive radiation dosages to the left hemisphere of my brain have caused irreparable neurological damage to my cochlea, which has ceased functioning.

There may be options (cochlear implants) but I will not know more for several weeks. As you can imagine, this is a devastating blow to my personal life and music career, especially since I remember fighting so hard to regain dexterity and muscle control in my left hand when it ceased functioning prior to my initial diagnosis in 1995.

That said, it has only reinvigorated me to stay the course and continue to advocate on behalf of the more than 500,000 young adults living with, through and beyond cancer each and every year. Now more than ever, I stress the importance of recognizing that remission is not a cure and that public awareness and adequate funding for adolescent and young adult cancer survivorship programming is tantamount to that of cancer research.

This is what it means to be a cancer survivor.

To read more about Zachary's powerful journey, click here for an unbelievably moving essay -- titled The Cost Of Living: No Cure For Cancer -- written by this unbelievably grounded guy.

Reach for BEYOND -- tomorrow

Tomorrow, the second issue of Beyond: Live & Thrive After Breast Cancer hits newsstands. And I, for one, can't wait to pick up a copy of the Spring/Summer edition of this positively powerful publication.

If you read the first issue -- the Fall/Winter magazine released in October -- you know what this glossy book has to offer. There are personal stories and interviews, shared wisdom and sound advice. There are exercise tips and health tips and survival tips. There are stories about chemo brain and fertility and relationships. There is information about breast cancer research and resources and products that are tried and true.

I want to tell you so much more -- but really, I want you find out for yourself just how moving and soothing this magazine can be.

So plan to get your copy -- tomorrow -- and tell all your friends to do the same. If you need a gift for a loved one newly diagnosed or someone who has long survived this disease, try this on for size. Buy a few copies and donate them to your favorite doctors' offices -- a fresh magazine can do wonders for any waiting room. Share one with a neighbor, a relative, a new acquaintance.

Do what you can, will you -- to both reap the benefits of this solid source of inspiration and help sustain the life of this magazine? Because magazines are only as strong as the readers who embrace them. And trust me, this is one catch we cannot afford to lose.

Breast cancer weighs heavily on young emotions

Research indicates that young breast cancer survivors have a harder time recovering emotionally from cancer than women who develop the disease later in life.

In Australia, a quality of life survey including 300 women found most survivors adjusted normally within 18 months after diagnosis. But women under the age of 50 reported more of a struggle with their emotional health.

Perhaps it's the direct threat to her life, or her fertility, or her sexuality, or her body image that brings on the added challenge for a young woman. Regardless, there are no easy solutions or quick remedies for lightening the load that weighs heavily on young minds.

Breast cancer changes everything, and bouncing back from the disease takes time. And this research validates the need for programs targeted at younger women, as well as further research to more clearly identify how to better help breast cancer's youngest victims.

Young women's breast cancer conference

I wanted to remind anyone who is interested in attending the 7th Annual Conference for Young Women Affected by Breast Cancer that it is being held this weekend in Arlington, Virginia.

I will be attending and plan on giving updates over the weekend on the many different seminars and workshops. This will be my fifth conference since I was diagnosed in December 2001. It is such an amazing experience.

The seminars and workshops are very informative and you can pick and choose different topics depending on where you are in the treatment process or if you are newly diagnosed with breast cancer or have had a recurrence. There is something for everyone who is a young breast cancer survivor.

I also enjoy being in a room filled with women who are now not just other young survivors but friends.

My friend Deb and I were diagnosed only a few days apart and met on the YSC message boards. She came to visit me this weekend and we celebrated reaching the milestone of five years of survivorship!

www.youngsurvivorsconference.org

Chemopause may help women survive breast cancer

Some women opt to remove their ovaries to prevent breast cancer recurrence. I considered it -- and then decided I would not take such an extreme measure when I wasn't all that sure I was done having children.

Now, ovary removal may not be necessary -- because a new chemical equivalent of surgery allows women to temporarily shut down their ovaries while preserving their fertility.

The shutdown of the ovaries is called chemopause, and women who choose to go this route receive monthly injections -- considered a super-hormone treatment -- of a drug that blocks the male hormone testosterone and is often used to treat prostate cancer.

Chemopause has big advantages. It doesn't require surgery. And it's not permanent. Women who want to have children can stop the treatment in order to conceive. And women who have trouble with side effects can discontinue use of the surgery-sparing drugs.

The ovary-suppressing drugs -- triptorelin, goserelin, leuprolide, and buserelin -- can be used in place of or on top of standard chemotherapy and hormone therapy and are showing promise in their ability to decrease incidences of breast cancer recurrence.

Medical professionals agree there is value in ovarian suppression. Studies show women whose periods do not return after chemotherapy -- which often causes early menopause -- have lower relapse rates than women whose periods resume. So shutting down the ovaries and stopping menstruation may not be such a bad idea -- and not such an extreme measure either.

I'm Too Young For This! teens and young adults with cancer

I'm Too Young For This! (i2y) is a recently launched portal for adolescent and young adult (AYA) cancer survivors. Featured i2y resources and support services include survivor spa retreats, online forums and blogs, social networking, camping excursions, fertility education, peer counseling, and financial scholarships.

"The i2y website is primed to become a premiere online resource for AYAs with cancer by eliminating the stress and hassle of navigating through thousands of search engine results," said Matthew Zachary, founder and executive director of Steps For Living and an 11-year young adult survivor of pediatric brain cancer. "Our goal to make I'm Too Young For This! the first place adolescents and young adults with cancer think of to go when in search of credible, targeted support programs, tools and services."

"This website is just what the doctor ordered. Now, with the click of a mouse, they can instantly connect with a universe of others just like them." Doug Ulman, Chief Mission Officer for the Lance Armstrong Foundation and a 10-year young adult survivor says, "We are pleased that Steps For Living is dedicated to making a difference in cancer advocacy for this community."

To raise awareness for the i2y organization, the AYA Steps For Living musician/cancer survivors have released a 21-track benefit CD featuring their original songs and music. You can listen to the playlist here. Included in the album is an i2y online resource guide.

The tagline of i2y reads: Got Cancer? Under 40? Sucks, huh? Get Busy Living. Indeed, if you are between the ages of 15-39, i2y is a destination meant just for you. If you are a caregiver or friend of a teen or young adult who is facing the challenges of cancer survivorship, let them know about i2y. This is a phenomenal group of artists, musicians, writers and photographers who, as young adult cancer survivors, got busy living. Visit I'm Too Young For This! to learn more.

Cancer by the Numbers: Cervical Cancer

Cervical cancer was once the most common cancer in women. But between 1955 and 1992, the number of cervical cancer deaths dropped by 74 percent -- thanks to increased use of the Pap test, a screening tool that can find changes in the cervix before cancer develops and can also detect cancer in its most curable stage. The Pap test is still widely used. And the cervical cancer death rate continues to drop four percent every year.

In 2006, about 9,700 new cases of invasive cervical cancer will be diagnosed in the United States. About 3,700 women will die from the disease. Non-invasive cervical cancer is believed to be four times more common than the invasive form of the disease. Nearly all of these cases can be cured.

Cervical cancer typically occurs in women between the ages of 35 and 55 and rarely in women under the age of 20. It affects mostly Hispanic women, and African-American women develop the disease 50 percent more often than non-Hispanic white women. Women most as risk for cervical cancer are smokers, those with HIV or chlamydia infections, those with diets low in fruit and vegetable consumption, those who between 1940 and 1971 took the hormonal drug DES, and those who have taken oral contraceptives for extended periods of time. Women who have had multiple pregnancies, have a family history of the disease, and have a low socio-economic status are also at risk. Those most at risk, however, are women with human papilloma virus.

Human papilloma virus (HPV) is the most common risk factor for cervical cancer, and some experts believe a woman must have HPV to contract cervical cancer. There are 100 different types of HPV, 13 of which are likely to cause cervical cancer through sexual contact. There are usually no symptoms of HPV, but possible signs of cervical cancer can include vaginal bleeding, unusual discharge, pelvic pain, and pain during sexual intercourse.

There are two ways to stop cervical cancer. First, women can protect themselves against HPV. Protection comes in the form of delaying sexual activity, limiting the amount of sexual partners and their partners, using condoms (thought to be 70 percent effective) and receiving the cervical cancer vaccine, recommended for use in females ages 11-26. The vaccine is most effective for women who have never been sexually active. Second, women can receive regular Pap tests in order to catch pre-cancers. Pap tests are recommended for women three years after their first sexual encounter and before the age of 21 -- and then every year after that.

An abnormal Pap test typically prompts a colposcopy -- a technique that uses a scope to examine the cervix. Diagnosis usually stems from a combination of other scoping methods, pelvic exams, imaging tests, and biopsies used to confirm the presence of cancer and to stage the disease. Stages range from 0-4.

For non-invasive cervical cancer, surgery -- ranging from removal of the cancerous tissue to hysterectomy -- may be the only treatment necessary. For invasive forms of the cancer, surgery is often followed by radiation and chemotherapy. Women interested in preserving their fertility should discuss options with their physicians.

The state of cervical cancer has come a long way over the years. And this year, two critical developments emerged. In June 2006, the FDA approved the first drug for late-stage cervical cancer. The drug, Hycamtin, is recommended for use in combination with chemotherapy. Also is June, the cervical cancer vaccine, Gardasil, was released. Both developments are monumental -- and both will undoubtedly help decrease the already-dropping cervical cancer death rate.

For more information about cervical cancer, visit the following sites:

American Cancer Society
Mayo Clinic
Medline Plus
National Women's Health Information Center

Cancer by the Numbers: Testicular Cancer

Testicular cancer, cancer in one or both of the testicles, usually occurs in young men and will strike about 8,250 of these men this year. About 370 men will die.

A man's lifetime risk of developing this cancer -- that typically shows up in only one testicle -- is 1 in 300, securing it as one of the less common cancers in the United States. The chances of dying from testicular cancer are 1 in 5,000, making it one of the most curable forms of cancer. Yet it is still the most common form of cancer in men ages 15-34. It is also a cancer commonly characterized by denial and embarrassment. As a result, it is one of the least mentioned cancers.

Continue reading Cancer by the Numbers: Testicular Cancer

Baby after breast cancer diagnoses

A member of the Young Survival Coalition named Julie agreed to share her story of having a child after breast cancer.

I asked Julie if she thought that hearing other stories of women having a baby after breast cancer gave her comfort knowing it could happen for her. (That was my reason for me wanting to write this blog post in the first place.) Julie says "I did find comfort in hearing about success stories but I was also very cautious." She was unsure when she met with a fertility specialist how far she wanted to go with the treatments to help her get pregnant. Julie's advice is to find a fertility specialist that will make all medical procedures open to you.

Julie was diagnosed with and 8cm tumor of DCIS and two other tumors that were invasive. Julie received four rounds of Adriamycin and Cytoxen and then four rounds of Taxol. She was told to wait two years before she could try and get pregnant. Her tumor was estrogen negative. Julie was worried that the chemotherapy regime she received would affect her fertility.

She was told there was not much hope in her getting pregnant on her own however Julie was able to get pregnant with no medical intervention. She was 38 at the time. She now has a boy named Michael.

She would like to tell other young breast cancer patients that there is always hope. She doesn't like to brag about getting pregnant to others because she knows that for every one of us that gets pregnant, there are many of us survivors that can't.

Julie says that "she believes Michael was a gift. I look at him everyday and am amazed that he is my son"

Tampa breast cancer conference kicks off awareness month

At the end of the September 30 FACTors Breast Cancer Educational Conference in Tampa, Florida, there will be a passing of the torch ceremony to celebrate the end of Ovarian Cancer Month and the start of Breast Cancer Awareness Month. But first, conference participants can gather a whole lot of information on a whole lot of topics at this 19th annual conference, hosted by the Tampa-based H. Lee Moffitt Cancer Center & Research Institute. The conference -- with a registration fee of just $25 -- includes breakfast, lunch, an art exhibit, and a variety of educational sessions which span topics such as healthy eating and exercise, genetic connections, fertility, sexuality, early onset menopause, caregiving, relaxation, communicating with children about cancer, and shaping the future.

Actress and breast cancer survivor Lynn Redgrave's daughter, Annabel Clark, will deliver the keynote address and will discuss her book, Journal: A Mother and Daughter's Recovery From Breast Cancer. There will be exhibits and door prizes and a special lunch guest too -- breast cancer survivor Dee Dee Jonrowe, the world's top female dog sledder and 23-year veteran of the Alaskan Iditarod race.

From 8:00 AM to 4:00 PM on September 30, the topic of breast cancer will be top priority for all who attend this conference in Tampa. And then the next day -- which kicks off the month of October -- breast cancer will be top priority all over the country when Breast Cancer Awareness Month commences. And we pay special attention to this disease that already gets a lot of special attention. Fortunately.

Fighting for Our Future: Young women and breast cancer

Fighting for Our Future:How Young Women Find Strength, Hope, and Courage While Taking Control of Breast Cancer. Beth Murphy spent two years studing young women with breast cancer and her book gives young women a valuable resource.

Fighting for Our Future talks about many issues related specifically to women under forty diagnosed with breast cancer. Some of this issues are fertility, pregnancy, negotiating treatment, living with the illness, sexuality and dating. It reaches out to the newly diagnosed and those living with metastatic disease to all in between.

Breast Cancer patients tell their own stories throughout sections of the book. They decribe treatment and procedures and give the real information that the young women need to know.

Little known procedure saves fertility

Several days ago, the American Society of Clinical Oncology issued new guidelines concerning the preservation of fertility during cancer treatments. Many treatments for cancer will lead to infertility if precautionary measures are not taken before treatment begins. The two methods of fertility preservation with the highest likelihood of success for cancer patients are embryo cryopreservation for women and sperm cryopreservation for men. Today, I came across a news story describing another option called ovarian transposition. In the article about dreams surviving cancer, surgeons made tiny incisions in Carrie Lintner's abdomen and gently pulled her ovaries behind her uterus, where they were held in place with a few stitches. The uterus shielded her ovaries from the damaging radiation beams from the treatment she received for her recurrent Hodgkin's lymphoma. The ovarian transposition procedure took 30 minutes and saved her ability to give birth. Ms. Lintner, who is now cancer-free, is the mother of a baby girl, Maia.

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