Researchers have made a stem cell discovery that may help treat pancreatic cancer -- one of the deadliest forms of the disease.

University of Michigan scientists have found cancer stem cells in pancreatic tumors that appear to drive cell tumor growth and could lead to the development of drugs to target and kill these cells.

Pancreatic cancer kills 97 percent of people diagnosed with the disease within five years. Half of all diagnosed patients die within six months of diagnosis, and this cancer -- that spreads quickly and is rarely detected at an early state -- kills 33,000 each year in the United States alone. So any improvement in the study of this disease is a true gift.

"The clinical implications of this work are significant," said Dr. Diane Simeone, director of the Gastrointestinal Oncology Program at the University of Michigan Comprehensive Cancer Centre and lead author of the study, published in the journal Cancer Research.

"We've made baby steps in improving the survival in these patients -- on the order of a few months (longer to live) -- over the past decade or so. But we really haven't had a major breakthrough in coming up with something that has the potential to provide a cure," she said.

Simeone says killing these cancer stem cells is like pulling out the root of a weed. And she says the best way to pull out the root is to target these stem cells instead of the traditional approach of shrinking tumors by killing as many cells as possible -- an approach that may be flawed because cancer stem cells tend to resist standard therapies.

Americans are urged to know their family medical histories -- and to share them with their doctors.

Spearheaded by the U.S. surgeon general's office and other public and private agencies, this urging is critical -- because knowledge of family history can lead to more frequent and earlier screenings for particular cancers, to changes in diet and exercise to combat onset of heart disease and diabetes, to more formal genetic counseling and testing if warranted.

This Thanksgiving marked the third anniversary of Thanksgiving National Family History Day, a day the surgeon general's office has reserved for family discussion and documentation of medical histories.

"Family history itself is the first and best genetic test," says Sharon Terry, president of Genetic Alliance, a non-profit group in Washington, D.C.

Brigham and Women's Hospital in Boston has started a work-place initiative regarding medical family history. In the past year, about half of the 13,000 employees -- from physicians to file clerks -- have completed the computerized family history forms developed by the surgeon general's office.

Acting surgeon general Kenneth Moritsugu says, "knowing your family history can help you make better health choices. Much of what we do in American health care is treat chronic diseases, many of which involve choices over a lifetime."