David Foster was diagnosed with Advanced Renal Cell Carcinoma in April 2005. Translation: stage four kidney cancer and the sixth deadliest form of cancer. Not a great disease to acquire. Also not the end of the world. Just ask David who is busy working as a National Strategic Advisor in Augusta, Georgia, headlining within the independent magazine community, hanging out with dog Gracie, and documenting his journey in a blog he calls David Foster's Kicking Kidney Cancer's Arse.

He's no wimp, this guy. Just read his June 23 post, titled May kill me, but it ain't gonna beat me. He didn't let that hard-nosed kid Jerry whip him when he was eight -- he smacked him so hard in the lunchroom, Jerry was left stumbling and bleeding -- and he won't let cancer bully him either. Still, David admits: he is sick. He explains it all in a post he calls Mr. Foster, are you really sick?

David got an e-mail one day. It read, Mr. Foster, are you really sick? I read your blog and you don't sound sick.

A new study of mice implanted with human breast cancer cells shows the spread of the disease to the lungs -- a common metastasis site -- is caused by the abnormal activation of four specific genes working together.

The study, published in the journal Nature, indicates that shutting off the genes one by one can slow the growth and spread of this cancer. But turning off all four at one time almost completely stops the process. In mice anyway.

These genes are no strangers to researchers who have known for some time about their existence and functions. They just know more about them now.

The four genes work together at every step of the metastatic process to allow a breast tumor to develop blood vessels, let tumor cells enter the vessel walls and lungs, and permit them to pass out of the lung vessels and resume growth. New analysis shows that blocking these genes significantly reduces the tangle of blood vessels, making it harder for cancer cells to escape.

Researchers, who say the four genes are among 18 they associate with breast cancer metastasis, report that one implication of this study is clear: combined use of drug therapy may be more effective at inhibiting the activity of multiple gene targets.

The final nine episodes of HBO's Sunday night hit The Sopranos feature the stuff of life. You know -- blood, guts, betrayal, angst, and cancer. It's not quite the stuff of my life, well, except for the cancer part.

Actor Vince Curatola, who plays Johnny "Sack" Sacramoni, powerfully weaves cancer into the end of this popular television drama. Diagnosed with lung cancer, his character is given three months to live -- in a prison hospital bed.

Johnny Sack says very little in the last episodes. He does gasp to his wife in episode two, "I'm very, very sick," but he lacks the lung capacity to muster up much more. He disease is considered stage four.

The cancer depictions -- one shows Johnny Sack shuffling down a long corridor in his hospital robe, oxygen tank dragging behind -- are right on, say those who've taken an early peek at the shows. And reportedly, the cancer scenes pretty accurately reflect the concerns of the larger culture -- where cancer has become an epidemic that sadly, won't come to end in nine episodes.

Presidential candidate John Edwards and his wife Elizabeth will appear tonight on 60 Minutes where they will publicly discuss with Katie Couric Elizabeth's newest cancer diagnosis and their decision to continue on in the presidential race.

Elizabeth, 57 and first diagnosed with breast cancer in November 2004, shared Thursday that her cancer has returned, this time in her bones. Considered stage four and treatable -- but not curable -- her cancer has generated much discussion and awareness about the workings of this life-threatening disease.

To view a clip from tonight's news program, airing at 7:00 PM ET/PT, click here.

Elizabeth Edwards has been told the metastatic cancer found in her bones is considered stage four. And it's treatable. But not curable.

Tricky stuff -- all this cancer terminology -- and a little hard to fully comprehend.

I saw Sheryl Crow talking with Maria Shriver and Dr. Susan Love on Larry's King's CNN program the other night. Crow says her breast cancer was curable -- it was teeny tiny and had not spread and required a lumpectomy and radiation, but not chemotherapy. "I'm the walking poster child for early detection," she said. Her cancer was caught and treated swiftly. She is cured. Theoretically.

Can Crow's cancer still return? Yep.

We just aren't sure at the time of one cancer discovery if these deadly cells have drifted away from the main site and will later show up elsewhere, explained Dr. Love. All predictions would have Crow living a long life free of cancer. But they may have had Edwards in the same boat just two years ago when she was first diagnosed with breast cancer.

So now Edwards' cancer is not curable. It is treatable. And this is a bit easier to understand. Her cancer will never go away. But doctors can keep it at bay. And Love says they can even make it better. But there is no cure for what Edwards has. So she will live with cancer for the rest of her life.

I guess curable means: the cancer is gone and we hope it never comes back. And treatable means: the cancer is not gone and will never be gone but we will treat it for as long as we can.

I think I get it.

Elizabeth Edwards, wife of Democratic presidential candidate John Edwards, has had many routine medical follow-ups since her 2004 breast cancer diagnosis. And all of them -- until just a few days ago -- resulted in what is generally termed a clean bill of health.

The term doesn't always come with a sense of relief for those of us surviving breast cancer -- or any cancer for that matter -- because it only really defines what our bodies are telling us at one specific moment. There are no magic blood tests, no special body scans, no conclusive ways of determining whether or not cancerous cells have gone astray and will one day surface again.

I asked my oncologist after my first six-month follow-up how he would know if my cancer returns. He told me it's really up to me to determine whether it comes back. It's up to me to get mammograms and ultrasounds and MRIs. It's up to me to report any symptoms and suspicions. It's up to me to track my general well-being so that it will be clear when something feels not-so-right. If I have a persistent cough or headaches that won't subside, my doctor will take action with X-rays and scans and tests. But as long as I feel fine and nothing troubling presents itself, then I remain in the clean-bill-of-health club.

Edwards no longer has a clean bill of health. But she is determined to use her newest diagnosis -- stage four metastatic cancer of the bones, considered treatable but not curable -- to work toward the best health she can acquire for as long as she can hold onto it. And that is about as good as any of us can do.

I guess the concept is happy -- the public urging for our world's policy makers to make cancer a top priority -- but the fact that becomes all too apparent on this World Cancer Day is quite sobering. More than seven million people die from cancer and close to 11 million new cases are diagnosed worldwide each year. In 2006, cancer killed more people than AIDS, malaria, and tuberculosis combined.

So today is both happy and sad. But for now, let's focus on the happy.

The Geneva-based International Union Against Cancer (UICC) and member organizations in 86 countries are launching a five-year campaign to impart life lessons to children so they can prevent cancer later in life. Parents are critical in this campaign and must take an active role in teaching their children techniques for saving their lives.

Forty-three percent of cancer cases can be prevented through healthy lifestyles that begin in childhood. The World Cancer Campaign slogan -- Today's Children, Tomorrow's World -- underscores the possibility that a concerted effort among world leaders, parents, and their children can make a real difference through four key actions -- providing a smoke-free environment for children; ensuring children keep physically active, eat a healthy diet, and avoid obesity; educating children about vaccines for virus-related liver and cervical cancers; and limiting children's exposure to the sun.

Former First Lady Barbara Bush, Her Royal Highness Lalla Slama of Morocco, Nigerian President Olusegun Obasanjo, and tennis star Steffi Graf are some of the powerful voices powering this campaign that UICC president Dr. Franco Cavalli says can save so many lives if embraced by those at the highest decision-making levels.

"Complacency and inaction on the part of world community will effectively contribute to more than 10 million deaths every year by 2020," he said.

I am jingling and jangling with charms around my wrist once again. Ever since I was diagnosed with breast cancer, my friend Nicole has sent me a Brighton breast cancer bracelet. My very first bracelet arrived in 2004, and I wore it proudly. My second bracelet arrived in 2005 and took the place of the first. And now, as I enter my third year of survival, my 2006 Power of Pink bracelet dangles from my arm.

This year's bracelet features a heart-shaped locket. Other charms -- designed to represent stepping stones to recovery -- feature key survival terms. Brighton tells it like this -- "When we accept, we open the door to trust and find love that will heal. Along the way, we learn to be the inspiration." And there are still more charms -- a breast cancer awareness ribbon signifying a fight for the cure, a four leaf clover to assure luck is on our side, silver beads for richness, clear crystals for truth and purity. And still, there are more.

Brighton recommends we all make a difference in the breast cancer crusade. Some may choose to chip in by contributing financially. Some may volunteer. Some may lend a sympathetic ear to others in need. Some may purchase and wear the 2006 Power of Pink bracelet -- proceeds benefit breast cancer research -- and this one simple act will send an empowering message to women everywhere.

Two months ago, Wal-Mart launched its $4 dollar generic prescription drug program in Tampa, Florida. Two weeks ago, the program was expanded to include all Wal-Mart and Sam's Club pharmacies in 14 additional states -- Alaska, Arizona, Arkansas, Delaware, Illinois, Indiana, Nevada, New Jersey, New Mexico, New York, North Carolina, Oregon, Texas and Vermont.

314 generic prescription drugs, accounting for 25 percent of prescriptions it currently dispenses in its pharmacies nationwide, are available under the $4 dollar program.

For those with health insurance, the typical co-pay for the 314 generic drugs in Wal-Mart's $4 dollar generic prescription drug program cost between $5 dollars and $10 dollars. While the savings might not seem like much for people with health insurance, the co-payments can add up each month. For those on limited incomes, any savings is welcome relief. For the 46 million uninsured patients who live in one of the 15 states where this program is available, the savings can amount to much more, and may be one of the few times they have been offered a break when it comes to medical costs.

The generic drug list is available as a PDF document here.

Almost two months ago, we posted that the U.S. Food and Drug Administration, FDA, was fast-tracking a potentially promising new drug to help smokers quit smoking. In earlier clinical trials, Chantix, varenicline tartrate, worked in ways that previous smoking cessation drugs did not, indicating a higher success rate where other drugs had failed.

Chantix acts on the areas of the brain affected by nicotine and helps those who smoke cigarettes to quit smoking in two ways: by providing some nicotine effects to ease the withdrawal symptoms and by blocking the effects of nicotine from cigarettes if they start smoking again.

Now, according to three studies published in the July 5 Journal of the American Medical Association, it is being reported that Chantix quadruples the chances that a smoker can quit smoking and is twice as effective as the currently prescribed drug Zyban. Keep in mind though, the research was funded by the drug maker, Pfizer, and experts warn that the drug is far from a perfect solution for smokers trying to quit -- and "definitely not a panacea for smoking cessation."

According to Dr. Steven Galson, Director of FDA's Center for Drug Evaluation and Research, "Chantix therapy has proven to be effective in smokers motivated to quit and will provide another tool for physicians to use for the millions of smokers who want to quit." I believe this is a more realistic assessment of the ability of a medication designed to help smokers quit smoking.

UPDATE: Chantix: quit smoking drug now available in US pharmacies.

I have a Vera Bradley purse -- a backpack, actually -- that is black with pink ribbons and little multi-colored flowers sprinkled all over the fabric. The print is called New Hope and a portion of the proceeds from the purchase of this bag go toward breast cancer research. Now there is a second print available that also carries hope for a cure. Hope Toile is the name of this bright, cheery, perfect-for-summer, pink bag -- and like the purse I have, part of the sales will benefit the Vera Bradley Foundation for Breast Cancer. Since 1994, Vera Bradley has raised more than four million dollars for breast cancer research and this pattern -- which also shows up on accessories such as umbrellas, wallets, belts, eyeglass cases, and watches -- symbolizes renewed hope for a cure. And while I don't have this purse yet, it is on my wish list for a time when I need something new and fresh and hopeful.