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Posts with tag growing

Rituxan improves long term survival for mantle cell lymphoma

Mantle cell lymphoma is a type of Non-Hodgkins lymphoma. It is a cancer that forms in the cells of the lymph system. Mantle cell lymphoma is considered to be a low-grade and slow growing lymphoma.

The standard of care treatment is usually the chemotherapy combination called MCP, mitoxantrone, chlorambucil, and prednisolone.

The Journal of Clinical Oncology says that the addition of Rituxan (rituximab) to the chemo combination of MCP as initial therapy can improve long term survival rates.

Since Rituxan has proved to have anti-cancer responses in other forms of NHL, researchers continue to evaluate how it can work in the treatment of various types of Non-Hodgkins lymphoma.

Continue reading Rituxan improves long term survival for mantle cell lymphoma

Tiny implants to broadcast status of tumors

Scientists from Harvard University and Massachusetts Institute of Technology (MIT) are developing a tiny implant that will allow doctors to see what's happening with tumors from the inside out.

If all proceeds according to plan, doctors will one day be implanting tiny sensors inside tumors to determine whether or not cancer drugs are shrinking the tumors. The sensors will also determine whether or not tumors are growing.

Cancer specialists have long wished for better methods of measuring the success of drugs. While blood tests can show if a drug has reached the bloodstream, they don't reveal much about the tumor itself. This small silicone cube, no bigger than two millimeters on each side and embedded in a tumor or lymph node, would remain in the body throughout treatment while essentially broadcasting what's going on inside the tumor.

MIT scientists hope to begin animal experiments within months. Their goal is to one day make the implant as thin as the pieces of led used in mechanical pencils.

This research, funded by the National Cancer Institute, is part of a long-term project to make medical technologies that will cure cancer. It's all part of journey toward complete targeted cancer treatment. And this little implant will have the power to communicate whether or not these treatments are working.

Cancer deaths down for second straight year

In 1971, when it was evident cancer deaths were rising, President Nixon and Congress declared a war on cancer. Finally, after 35 years, it seems we are winning the war.

Experts say the absolute decline in cancer deaths is quite amazing -- because our population is both growing and aging, both of which could contribute to an increased cancer death rate. But prevention, early detection, and early treatment are working wonders and are saving lives for three of the most common cancers -- breast cancer, prostate cancer, and colorectal cancer. More and more men are also surviving lung cancer due to cessation of smoking more than 20 years ago. The female lung cancer death rate is not declining, however, due to continued high rates of smoking.

The highest drop in deaths among the major cancers was for colorectal cancer -- thanks to effective screening methods. Deaths dropped by 1,110 for men and 1,094 for women.

According to an American Cancer Society review of U.S. death certificates, cancer deaths declined by 369 between the years 2002 and 2003. Between 2003 to 2004, the decrease was 3,014 -- more than eight times greater.

Experts predict cancer deaths will continue to decline over the years -- although some expect the obesity epidemic, which increases risk for all cancers, to pop the cancer death rate back up in the long run.

Young women and high grade breast cancer

Why is it that younger women have a more aggressive breast cancer? I don't think anyone really knows for sure. Throughout my cancer diagnoses and treatment I have met many young women who had pathology of grade three cancers. Grade one is the least aggressive and can also be called well differentiated. Grade three is the most aggressive and is also called poorly differentiated. Grade two falls in between and is considered moderately aggressive.

I belong to the Young Survival Coalition (YSC). I decided to poll women on the boards to see if the theory rang true that younger women have a more aggressive breast cancer. I polled the group and asked what grade their tumor was at diagnosis. One hundred and fourteen young women participated in the poll. Of course this is only a small sample of young women diagnosed with breast cancer.

Out of 114 women only 12 percent had grade one tumors, 22 percent had grade two and 67 percent had grade three.

A positive thing about having a highly aggressive cancer is that chemotherapy seems to work better on these tumors. Chemotherapy kills fast growing cells so it makes sense that the faster growing cells would be more susceptible to the treatments.

I had a grade one cancer. In a way it makes me happy that I did have a low grade and less aggressive cancer, however, I did have a positive lymph node. My tumor was not very large. It was only 1.5 centimeters. But it did already start to spread. I feel like that since my tumor was slow growing that it might take longer for metastasis to show up. So, I worry about that-among other things!

I do think that breast cancer in young pre-menopausal women is different from the post-menopausal group. It's good to see studies done on younger women so we can figure out better ways to treat our cancer. YSC seeks to educate the medical, research, breast cancer legislative communities and to persuade them to address breast cancer in women 40 and under.

Mister Rogers reminds people of all ages it's good to be alive

Our days start early now that Joey is in kindergarten and school begins promptly at 7:45 AM. His daddy gets him out of bed at 6:30 AM so he can have some time to wake to the world before shuffling out the door, and we've happily found that Mister Rogers' Neighborhood comes on at just this time. The same Mister Rogers that first appeared on television in Canada in 1963 and then in the United States in 1967 -- with a gentle man, Mister Rogers himself, spreading his calm but uplifting messages to children and nurturing personalities of kids everywhere.

The last original episode of Mister Rogers' Neighborhood was aired in 2001. And in 2003, Fred McFeeley Rogers died at the age of 74 after a brief bout with stomach cancer. But his legacy lives on as his show -- the longest-running PBS program ever -- still graces the television screen. I remember watching this show with my grandmother when I was a little girl. And now I get to watch it with my little boy -- who can also visit Mister Rogers on the PBS website.

Today, Joey and I started our day with a cheery little song, sung by the man who hated television and joined it only to bring about change -- to use this fabulous instrument to guide children in a positive direction. And here is what he sang this morning -- the song that is still playing in my head as I take on the day ahead of me.

It's such a good feeling to know you're alive.
It's such a happy feeling: You're growing inside.
And when you wake up ready to say,
"I think I'll make a snappy new day."
It's such a good feeling, a very good feeling,
The feeling you know that we're friends.

I hope it's a good day in your neighborhood.

Colonoscopy saves woman's life from silent cancer killer

Coletta Barrett believed her stomach pains were caused by a gall bladder attack after eating greasy fried food. She excused a tightening in her lower abdomen as irritable bowel syndrome, and she explained blood in her stool as a response to stress. Only after a referral to a gastroenterologist led to a colonoscopy did she learn that the upper portion of her colon was almost completely blocked by a large tumor -- a cancerous tumor. Barrett was diagnosed with colon cancer. Her colonoscopy saved her life.

Barrett never once predicted she might have colon cancer. She thought the disease mostly struck older people. She was just 42. Screening tests are not even recommended until the age of 50. She had no family history of this cancer and had no typical risk factors associated with the disease. She did not smoke, was not overweight, and drank very little. But she did in fact have colon cancer -- shocking as it was -- and doctors believed her tumor had been growing for 18 months before detected. Fortunately, Barrett learned that her cancer had not spread. And she learned a few other things that she now shares as advice -- from her survivor point of view. These tips come from an article about Barrett in the August 1 Women's Day magazine.
  • Barrett says, "know your body." And don't ignore or dismiss any changes that occur.
  • Don't let embarrassment stop you from seeking help. Some symptoms can be difficult to discuss -- such as change in size and frequency of bowel movements, bloody stool, cramping, and bloating -- but still ask your doctor about them. Early detection is critical, she says.
  • If diagnosed with colon cancer, learn as much as you can about the disease -- a well-informed patient has a better chance at a better outcome.
Barrett offers sound advice. And I think it is global advice. Knowing your body, discussing symptoms, and education after diagnosis are key for anyone. For everyone.

Green-fingered challenge for gardeners

Breakthrough Breast Cancer, UK's leading charity committed to fighting breast cancer through research and education, has hands down and without argument, some of the best fundraising campaigns around. They are fun and innovative and trendy. In a recently announced fundraiser, they are inviting gardeners with a "passion for digging, sowing and cultivating their gardens" to host a garden party for friends to raise money for cancer charity -- or to sell cuttings from the garden and donate the proceeds to cancer charity.

According to Breakthrough, Linda Clegg from Keighley, West Yorkshire has been using her garden to raise money for Breakthrough since 2000, she says: "When my friend Norma called to say she had been diagnosed with breast cancer it was a huge shock. She really impressed me when she told me months later, that she had become a £1,000 Challenger. Little did I guess that I too would be diagnosed with breast cancer and subsequently have been bitten by the bug to raise funds for Breakthrough's research."

"It was difficult during my six months of chemotherapy, but my husband was a tower of strength through it all. When I look back now some very positive things to came out of that dreadful time."

Now in its 15th year, Breakthrough's £1,000 Challenge is the charity's longest-running, fundraising campaign. Once a fundraiser reaches the £1,000 target, Challengers can honor someone they love by having their name permanently displayed on the £1,000 Challengers' Wall, at the Breakthrough Breast Cancer Research Centre. Over 5,000 supporters have become Challengers so far, and to date have raised over £12 million.

The Breakthrough Breast Cancer green-fingered gardening challenge certainly isn't the only fundraiser they have launched. To find out more, go here. Not only can you sign up to participate in existing fundraisers, it's quite possible learning about what people are doing to raise money for cancer research and services will inspire you to original ideas of your own.

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