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Posts with tag halt

National Cancer Institute risks budget cuts -- again

National Cancer Institute director John Neiderhuber worries the NCI 2007 budget could be slashed by five to 10 percent. And he worries that key cancer research will inevitably come to a halt as a result.

Worries stem from budget cuts proposed by President Bush. Cuts would cost the NCI between $36 million and $4.7 billion -- but Bush reports that NCI funding has doubled in the past 10 years and would still remain relatively high. And due to the recent American Cancer Society announcement that cancer deaths dropped for the second straight year, White House spokesman Tony Fratto says, "We're proud of the significant investment that we have made in cancer research. We're also proud of the results showing that researchers are delivering on that investment."

But researchers still worry. They worry cuts will undermine their successes. They feel like the rug is being pulled out from under them, just as they are making significant progress. They suspect 95 clinical trials could be postponed or cancelled, 3,000 patients could miss the opportunity of joining a trial, and some cancers will be completely eliminated from studies.

"There is a real cost in human life," says Allen Lichter, executive vice president of the American Society of Clinical Oncology, of the more-than-monetary toll budget cuts will take on NCI research efforts.

One study already on hold, pending funding decisions, is the next phase of a study evaluating whether a class of drugs called aromatase inhibitors, can prevent breast cancer. Another research group has opted to stop studying brain tumors. This is a huge loss to patients with this type of cancer, says Lichter.

It's a huge loss to all of us really -- because cancer will affect each of us in some way, some day. And so with cut budgets come cut hopes, cut dreams, and sadly -- cut survival.

Cancer growth slowed with new angiogenesis finding

This summer I had written a post about angiogenesis and Dr. Judith Folkman who had come up with the theory in the early sixties. Angiogenesis is a normal process in growth and development, as well as in wound healing. However, this is also the process that forms new blood vessels for cancer cells to survive and grow.

Angiogenesis and its complexities are still being studied so that new drugs can target the cancer's cells ability to receive a blood supply and grow. Researchers from the University of Wisconsin Madison School of Medicine and Public Health were studying a protein that regulates the maturation of blood cells and instead discovered a new part of the mechanism of angiogenesis.

The tests showed that a gene that makes a compound call NK-B can inhibit angiogenesis in four different ways which could be a promising way to halt tumor growth.

Emery Bresnick, the senior author on the study says "we have discovered a new peptide that clearly suppresses angiogenesis via a novel multi-component mechanism."

Resource for working women with cancer just a click away

I remember reading that Barbara Delinsky, novelist and breast cancer survivor, never shared her diagnosis of cancer until well after her fight was over. She feared the news would somehow halt her career in the publishing world. She wanted to remain untainted by disease in the eyes of her readers and bosses so she saved her secret. The secret is out now -- and is also part of a book she wrote called Uplift: Secrets from the Sisterhood of Breast Cancer Survivorship. She is in the clear now -- but she once feared the consequences of managing both cancer and her career.

The experts who offer a website resource at cancerandcareers.org believe that it is possible to combine cancer and career without fear or worry or secrecy. The advice provided on this site offers wisdom for working women and for employers and for co-workers. There is also a forum for shared stories -- where all of these individuals weigh in on their experiences. There are reading recommendations and a listing of available programs and services and a complete story about how this all came about.

Five years ago, the Board of Directors at Cosmetic Executive Women -- the preeminent nonprofit organization representing women in the U.S. and European beauty industries -- realized that five out of their 40 members had been diagnosed with cancer. Some told their colleagues at work and some did not. But all continued to work and experienced similar challenges. The fact is that work does not stop for all women who have been diagnosed with cancer. So the mission of this group is to help women, their employers, coworkers, and caregivers deal with this problem in the same way that they have learned to deal with problems at work -- strategically, knowledgeably, and effectively. With the right tools, stress and difficulty can be minimized. And this site is one great tool.

A survivor's tale: AA principles used during chemotherapy

"It's said that chemotherapy is like skiing in front of an avalanche. You do one thing wrong, and the avalanche is going to get you." -- Harvey Rushfeldt

Using the principles he learned in Alcoholics Anonymous, AA, helped Harvey Rushfeldt, 72, diagnosed with non-Hodgkin's lymphoma last October, create a strategy for successfully living through the often grueling ordeal of chemotherapy. Rushfeldt sees both cancer and alcoholism as mortal threats and he approached his cancer treatments with the same 12 step attitude and perspectives alcoholics adopt on the one-day-at-a-time road to recovery.

Continue reading A survivor's tale: AA principles used during chemotherapy

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