Researchers are reporting that a new vaccine designed to treat breast cancer appears to be safe in women with advanced disease. It showed signs of slowing down tumor growth too.

The Neuvenge vaccine, made by Dendreon Corporation -- maker of the Provenge prostate cancer vaccine -- targets the aggressive Her-2 positive form of breast cancer, which affects 20 to 30 percent of breast cancer patients. Using immune cells from a cancer patient's own body, Neuvenge is a tailor-made therapy.

Reports about Neuvenge, published in the Journal of Clinical Oncology, indicate the vaccine did not cause any serious side effects and of the 18 women who participated in the Phase I study, there was a reduction in the size of a tumor in one patient. In three other women, the disease seemed to stabilize for as long as a year.

Women treated with Herceptin (trastuzumab) in combination with chemotherapy for early stage breast cancer showed that after five years the risk of congestive heart failure did not increase with time.

The findings of the National Surgical Adjuvant Breast and Bowel Project (NSABP) were presented at the 43rd annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago last week.

Heart damage occurs in around 5 percent of patients treated with Herceptin. It is the most significant side effect; women with existing heart conditions cannot take the drug. The study showed that women were either susceptible to heart problems or they weren't. The risk of long-term problems is the same as the risk that is there from the beginning.

Peter Augustini's wife Jodi is fighting Stage IV breast cancer. They have three children, Charles, 10, Caroline, 7 and Max, 2.

Augustini is organizing a fundraiser to benefit the research Dana Farber Cancer Institute is using to help his wife fight breast cancer. He wanted to help Jodi and others fighting her type of aggressive breast cancer, referred to as Her-2 positive breast cancer.

Augustini decided to take on a holiday, Valentines day, that some people seem to think is a commercially contrived holiday. Augustini says "This is the chance to do something meaningful".

You can purchase a three inch wooden heart for your Valentine via the Share your Heart Fundraiser. The proceeds will benefit a fund specifically set up to fund research into a cure for Her-2 neu form of breast cancer. The research involves work on a drug called herceptin, which is attracted to specific proteins found only in cancer cells in the body.

The hearts are $5 each. You can also purchase a package of 10 for $20 and a package of 25 for $40. The hearts come unpainted and ready to decorate.

Share Your Heart Valentines are available for order vial the Dale, Wheelock and Memorial School Web sites, www.medfield.net or by e-mail to paugustini@cera.com.