According to an article published in the American Journal of Epidemiology, smoking is responsible for the majority of laryngeal cancer in Central Europe.

The majority of head and neck cancers are cancers of the larynx, or voice box. Central Europe has some of the highest incidence rates of laryngeal cancer in the world. Researchers are continuing to evaluate potential links between smoking and other environmental variables and the risk of laryngeal cancer.

Researchers from Europe recently conducted a clinical study to evaluate the potential role of both tobacco and alcohol in the development of this disease.

The study found:

• Approximately 87 percent of laryngeal cancer is attributed to the use of tobacco
• 75 percent of laryngeal cancer is attributed to current tobacco use
• 12 percent is due to past tobacco use
• Nearly 40 percent of laryngeal cancers are attributed to the interaction between alcohol and tobacco
• Stopping smoking for five years or longer protected individuals against the development of laryngeal cancer
• Alcohol use alone was not significantly associated with an increased risk of developing laryngeal cancer

The authors of the study states "Preventive efforts to encourage current smokers to quit are likely to be the most effective way to reduce the incidence of laryngeal cancer in this region"

The U.S. government's Institute of Medicine reported that asbestos, which is accepted as a cause of a number of respiratory ailments including lung cancer, may also be a source for laryngeal cancer. The larynx produces the sound of your voice. Each year in the United States, more than 10,000 people learn they have larynx cancer. Men are four times more likely than women to get cancer of the larynx. Occupational related issues are certainly a factor with mechanics, construction, and other jobs that handle asbestos.

A series of studies have found that certain cancers of the throat and lungs are similar, so the U.S. Senate asked the institute to investigate a potential link between asbestos and other upper-body cancers. Asbestos is also linked to mesothelioma which is a rare cancer that attacks the lining of the chest.

Smokers and smokers that drink alcohol are even more at risk to develop cancer of the larynx. Symptoms of larynx cancer are hoarseness or other voice changes,lump in the neck, a sore throat or feeling that something is stuck in your throat, a cough that does not go away, breathing problems, bad breath, earaches, and weight loss.

Studies exist that link acid-reflux conditions to cancer of the larynx -- or voice box -- but authors of a new study say they all suffer shortcomings in methodology.

The new study, published in the American Journal of Medicine, was intended to make up for these shortcomings by comparing 96 men and women with laryngeal cancer to a group of adults without the disease. All participants were matched by age, gender, and ethnicity -- three of the most important risk factors for this cancer. Overall, the study found people with GERD -- gastroesophageal reflux disease -- were twice as likely to develop laryngeal cancer, compared to those without the condition. GERD has long been considered a possible risk factor for this cancer, mostly because GERD is common among people with the cancer. More definitive studies are on the horizon.

GERD, which occurs when the muscle of the bottom of the esophagus fails to close properly, allowing stomach acids to leak into the esophagus, is also linked to esophageal cancer.