Prescription weight-loss drug Xenical hit drugstore shelves on Friday with a new name -- Alli (pronounced: "Al-eye") and with a new non-prescription strength. The newly-named drug is to be more effective with less unpleasureable side effects. Still, there's a problem surrounding this drug, regardless of its name. It's thought to cause colon cancer.

The nonprofit group Public Citizen says Alli, made by GlaxoSmithKline, has been shown in mice studies to cause pre-cancerous lesions in the colon. Since there are no long-term studies on humans, this group believes the FDA should not have approved the drug for non-prescription use. It's not clear whether or not the pre-cancerous spots will lead to colon cancer but the mere suggestion that it might is enough, says a Public Citizen spokesperson.

"What we do know is that these lesions occur much more frequently in people who do get colon cancer," he said. "Why do we recommend that everyone get a colonscopy at the age of 50? Because you pick up on these polyps when you do one. And, even though not all of the polyps are pre-cancerous, no (doctor) does a colonscopy without removing every single polyp that is found. And you do this because you know if you don't, it greatly increases the chances of getting cancer."

There are four pages in the March 2007 Reader's Digest featuring amazing discoveries, devices, tests, and cures. And many of the snippets of information are -- yes -- somehow linked to cancer.

Think about this:

• A new ultrasound technique lets radiologists distinguish between malignant and benign breast lesions. Using elasticity imaging, researchers accurately identified harmless and cancerous lesions in almost all of the 80 cases studied. If results can be reproduced in a large trial, this technique could significantly reduce the number of breast biopsies required.

• Scientists seeking new treatment for diseases can use an online tool developed by researchers at MIT and Harvard. The Connectivity Map matches diseases with compatible drugs, based on the genetic profiles of both. So far, about 160 drugs and compounds are cataloged, and a few new uses for existing drugs have already been suggested. Eventually, all FDA-approved drugs will be included.

• For those who sometimes forget to take their pills, a new device -- that can be preloaded with up to 100 doses of medication -- could one day be implanted in the body and programmed to administer drugs via wireless signals. This device, successful in tests using dogs, was designed to deliver medicines that are less effective when taken orally.

Sometimes it seems cancer's grip is tightening. Other times, in the war against this pesky disease, it seems we are on the verge of something really great.

A colonoscopy camera lets the physician check for abnormalities inside the colon. These can include cancerous or precancerous growths. The doctor guides a flexible scope though the colon, that can take about seven minutes, he then spends on average another six minutes withdrawing the scope evaluating inside of the colon.

The New England Journal of Medicine published a study that found colonoscopies that took a longer time to complete found more abnormal growths. Faster testing was shown to miss some abnormalities. Doctors who spent more than six minutes withdrawing the colonoscopy tube found more abnormal growths than those who withdrew it in less than six minutes.

The study did not have a conclusive answer as to exactly long physicians should spend withdrawing the tube. Other experts say to keep it in the range of six to ten minutes.

I know this is the last thing you want to say to your physician-- "Can you keep that up there a bit longer please?', but it might just save your life.

In the not-too-distant future, dermatologists will be able to diagnose skin cancer without ever cutting the skin.

Right now, doctors cut out all suspicious lesions in order to examine them, to determine if they are cancerous or not. But with the development of a new microscope, cells can be examined right on the body -- without cutting.

Moles matter, reported Matt Lauer on Thursday's TODAY show during an interview with a skin cancer expert. Moles are highly associated with melanoma, the deadliest form of skin cancer. So it is critical that each mole is investigated. With this new high resolution technology -- essentially a video biopsy -- a camera will allow doctors to view cells, zero in on the area of concern, and pinpoint the exact cells that make up a mole. If the cells are similar in shape and size and have equal distribution, the mole is normal. If the individual cells are irregular and have no uniform pattern, the mole is abnormal and probably cancerous.

While cutting for biopsy purposes will one day be a thing of the past, cutting will still be necessary if a mole is characterized by cancerous cells. If it's cancer, it must come out. But the video biopsy can be used to map the border and boundaries and will allow for precise removal of the mole.

This technology is still developing -- but one day, perhaps eight to 10 years from now -- doctors will be able to more consistently detect cancer without removal of skin. For now, they must take a piece of the mole and put it under a microscope.

There are definite warning signs of skin cancer. Any mole that is asymmetrical with irregular borders and varied, dark colors should be reported to a physician. Also, any mole that changes in color, shape, or size and is bigger than a pencil eraser is cause for concern.

Scientists have determined that mouth cancer develops in two different ways which dictates the seriousness of the disease. This finding, revealed on Tuesday, could lead to better prevention and treatment. In laboratory experiments with healthy, early, and advanced cancer cells, researchers were able to pinpoint differences in the cells that determined the aggressiveness of the cancer. They found faults in the p53 gene, which stops damaged cells from dividing, and in the p16 gene, which helps regulate and prevent cancer from developing. Both changes are linked to more aggressive tumors. This is first-time evidence that some mouth cancer tumors are more aggressive than others and are unfortunately linked to poor patient survival.

Oral cancer typically stems from pre-cancerous lesions, changes, or patches in the mouth -- all of which are early signs of cancer. Recognizing which pre-cancerous changes are more likely to develop into aggressive tumors would allow doctors an insight that could help them prescribe the best treatment.

Smoking, use of chewing tobacco, and heavy alcohol consumption are the leading causes of mouth cancer. And smoking and drinking are a very dangerous combination. Like lung cancer, mouth cancer usually develops in people age 50 or older.