Chemotherapy given before surgery to remove cancer is called neoadjuvant treatment. An oncologist might recommend this based of the size of the tumor -- it being very large. The idea is to shrink the tumor and then have surgery to remove the cancer.
Having chemotherapy administered while the tumor is still there can show what drugs are working and what drugs have no effect on the tumor. Chemotherapy when started immediately, not after surgery with healing time needed, gives the patient systematic treatment right away. This could be beneficial and is why physicians might recommend this form of treatment. The truth is they don't know if it is better or not.
Of course, every case of breast cancer is different. We all need to make tough decisions regarding our treatment plan. The facts are that currently there is no evidence that survival is improved with neoadjuvant verses adjuvant (after surgery) chemotherapy in women with locally advanced breast cancer.
The clinical trials that are done help physicians understand what treatments are more effective. Results from a Phase II clinical trial was published in the Journal of Clinical Oncology. It stated that neoadjuvant treatment with Taxotere, Navelbine, and Herceptin resulted in a complete disappearance of detectable cancer in 39 percent of women with locally advanced HER2 positive breast cancer.
The study showed that after two years followup, on the thirty one women with locally advanced breast cancer involved in the study, the overall survival was 97 percent and cancer free survival was 84 percent.
So, the message here is that, even though the study group was small, the results showed a good response to this treatment plan.


In previous studies there has not shown to be an increase in survival when adding chemotherapy after surgery for gastric cancer compared with surgery alone. Most U.S. patients that are diagnosed with cancer of the stomach or lower esophagus have locally advanced disease that is hard to cure.
Where does the time go? Even though most of us have been experiencing the height of the summer season in the form of a nationwide scorcher of a heat wave, summer is almost over for school kids and teens leaving for college. Yes, in less than a month, it's back to school. There are advertisements everywhere you look for new school supplies and new school clothes. In preparation for the new school season, Duke Health has published
Young women sometimes are dismissed when they pursue medical attention for suspicious lumps, bumps, pains, or changes in their breasts -- because breast cancer is not so common in young women and medical professionals may assume that breast cancer is not the culprit for the complaints brought before them by young women. But young women do get breast cancer -- I did at age 34 -- and many times, the tumors found in young breasts are more aggressive than those that appear for older women. So it is critical that young women seek medical attention for anything out-of-the-ordinary. And it is critical that doctors respond with urgency so that breast cancer in young women can be detected early -- and treated appropriately.







