Make smart financial decisions with DailyFinance

Note: The contents of this blog are for informational purposes only and should not be construed as medical advice or substitute for professional care. For medical emergencies, dial 911!

Posts with tag malignant

Stem cells may look, but not act, like cancer

I love it when I find research coming straight from the halls of the very hospital where I received my breast cancer treatment. It reminds me that I'm in good hands, that University of Florida researchers are on the cusp of breaking through the mysteries of cancer, that I may one day be the lucky recipient of cutting-edge discoveries, like this:

University of Florida researchers report in a paper to be published in the August issue of Stem Cells that bone marrow stem cells attracted to the site of cancerous growths often take on the appearance of the malignant cells surrounding them. While these cells look like cancer, though, they may not act like cancer. They have the same skin, says lead study author Dr. Chris Cogle. But the question is: do they have the same guts?

"Our results indicate these cells act as developmental mimics; they come in and look like the surrounding neoplastic tissue, but they aren't actually the seed of cancer," said Cogle who is affiliated with the cancer center I've called home for more than two years.

Continue reading Stem cells may look, but not act, like cancer

Is Farrah Fawcett's cancer back?

The National Inquirer was the first to break the news about Farrah's diagnosis of anal cancer before the star confirmed it.

The same paper is now saying that Farrah's cancer has returned. According to the article, doctors have found a small, malignant polyp. The actress was previously treated with radiation and chemotherapy. The new plan would be to place a small metallic seed in the area that would kill the cancerous polyp.

Can't believe everything you read -- especially from this source. Even if it is true that her cancer has recurred, I think most of what is said in the article is probably wrong.

Is targeting stem cells the way to cure cancer?

Some scientists think that the reason cancer recurs is because we haven't gotten to the root of the disease. What they mean by the root is -- the cancer stem cells.

Stem cells can reproduce and make exact copies of themselves and can live longer than ordinary cells. Embryonic stem cells can have the potential to become many different types of cells, whereas adult stem cells are generally limited to becoming into the cell types of a specific organ.

The researchers gave the analogy of a dandelion that is growing in your backyard. You can cut the weed but if you don't kill the root the dandelion will grow back. It seems that our treatments today for cancer can kill the ordinary cancer cells but can leave the stem cells behind to grow into new tumors and spread.

So how do we kill the cancer stem cells? Well, they don't know yet. But it is promising research that I look forward to hearing more about in the future.

Thought for the Day: On the verge of something great

There are four pages in the March 2007 Reader's Digest featuring amazing discoveries, devices, tests, and cures. And many of the snippets of information are -- yes -- somehow linked to cancer.

Think about this:
  • A new ultrasound technique lets radiologists distinguish between malignant and benign breast lesions. Using elasticity imaging, researchers accurately identified harmless and cancerous lesions in almost all of the 80 cases studied. If results can be reproduced in a large trial, this technique could significantly reduce the number of breast biopsies required.
  • Scientists seeking new treatment for diseases can use an online tool developed by researchers at MIT and Harvard. The Connectivity Map matches diseases with compatible drugs, based on the genetic profiles of both. So far, about 160 drugs and compounds are cataloged, and a few new uses for existing drugs have already been suggested. Eventually, all FDA-approved drugs will be included.
  • For those who sometimes forget to take their pills, a new device -- that can be preloaded with up to 100 doses of medication -- could one day be implanted in the body and programmed to administer drugs via wireless signals. This device, successful in tests using dogs, was designed to deliver medicines that are less effective when taken orally.
Sometimes it seems cancer's grip is tightening. Other times, in the war against this pesky disease, it seems we are on the verge of something really great.

Cancer drug Avastin fights brain tumors too

Lung and colorectal cancer drug Avastin has been tested for the first time against the most common and deadly form of brain cancer.

Duke University researchers used Avastin, known chemically as bevacizumab, in combination with a standard chemotherapy agent in patients with recurrent brain tumors called gliomas. Good news -- the two drugs together stopped tumor growth for twice as long as any other therapy.

Gliomas are mostly incurable in all cases, but this new treatment approach may extend life and may help preserve physical and mental function for a longer period of time for patients fighting this deadly disease.

"These results are exciting because of the possible implications for a patient population that currently has the poorest possible prognosis going into treatment -- those with malignant brain tumors that have recurred after initial treatment," says the lead researcher whose findings appear in the journal Clinical Cancer Research.

NASCAR driver Bobby Hamilton dies of cancer

Longtime NASCAR driver Bobby Hamilton -- winner of the 2001 Talladega 500 and champion of the 2004 Craftsman Truck Series -- died Sunday of cancer. He was 49.

Hamilton was diagnosed with head and neck cancer in February 2006 after a malignant growth was found when swelling from dental surgery did not resolve.

Despite his diagnosis, Hamilton went on to race in the year's first three events, with a best finish of 14th at Atlanta Motor Speedway.

"I love what I do; I love this business," Hamilton said. "NASCAR has been good to me, and I just don't feel comfortable when I am not around it."

Hamilton did turn over the wheel to his son, Bobby Hamilton Jr., for a short time while undergoing chemotherapy and radiation -- and then he was back to the races in August when CAT scans revealed he looked healthy.

But he learned all too quickly that microscopic cells remained on the right side of his neck.

"Cancer is an ongoing battle, and once you are diagnosed you always live with the thought of the disease in your body," Hamilton said. "It is the worst thing you could ever imagine."

Hamilton, who drove in all of NASCAR's top three divisions, had four wins under his belt in what is now the Nextel Cup series. His wins came at Talladega, Phoenix, Rockingham, and Martinsville, and his best ever season was in 1996 when he finished ninth in the points standings. Also winner of 10 truck races and one Busch Series race, Hamilton boasted earnings of $14.3 million, raced to 20 top-five finishes, and became a full-time driver-owner in the truck series in 2003.

Another NASCAR favorite, Benny Parsons -- 1973 Winston Cup champion -- was diagnosed with lung cancer in July. He was admitted to intensive care last week at a North Carolina hospital.

Ohio State football coach tackles cancer

Ohio State quarterbacks coach Joe Daniels is part of a coaching staff preparing to take on the University of Florida in the NCAA Football National Championship in Glendale, Arizona next week. It's a big game, with big stakes -- but it's just one match-up Daniels plans to tackle this year. He's also in the midst of a game with cancer -- a game he plans to win.

Daniels, a 64-year-old assistant to head coach Jim Tressel and contender for the Broyles Award, given January 16 to the nation's top assistant coach, was diagnosed with kidney cancer this past year shortly after suffering a heart attack and while mourning the death of his mother. Although it was a tough year, he still managed to make it through his 37th season as an assistant coach. He and his wife, Kathy, say it's been a hard road but a blessed one too.

"Cancer is a terrible disease," says Kathy. "But in a lot of ways, it's enriched our lives. It's not the burden a lot of people expect it to be. Maybe it's because we've been so fortunate to have football as a distraction."

The Buckeyes' 12-0 season -- complete with a Heisman Trophy victory for quarterback Troy Smith -- was quite a distraction for Daniels who was able to avoid chemotherapy and radiation and is faithfully taking a drug called Sutent to treat his malignant tumor. He takes a pill for 28 days, then takes 14 days off, and then begins again.

Medically, everything seems to be working out just fine for Daniels. His monthly check-ups continue to deliver good news, and he reports he has felt good, with just a bit of fatigue, for the entire season.

Now about that other game. Tune into the FOX network on Monday, January 8 at 8:15 PM -- and watch it all unfold.

Revolutionary breast cancer screening device

The National Institutes of Health (NIH) has awarded Techniscan Medical Systems (TMS), a Utah-based company that has developed an ultrasound imaging system known as UltraSound CTTM, a $2.8 million dollar small business grant to go forward with a radiation-free, non-invasive, breast cancer screening device that does not compress the breast during examination.

How does it work? While a woman is lying face down, the breast is suspended in warm water and an ultrasound scanner rotates in a circle, producing detailed 3-D images. According to the company, the diagnostic imaging tool will be able to detect normal, benign and malignant tissues in the breast.

To learn more about the UltraSound CTTM, visit the TMS website.

Marathon runners face skin cancer risk

It's not surprising marathon runners face an increased risk of skin cancer due to long-term sun exposure. What's surprising is that so many are not taking measures to protect themselves from the sun's damaging rays.

A team of Austrian researchers, all of them dermatologists, became interested in studying long-distance runners when they realized they had collectively treated eight ultra-marathon runners with malignant skin cancer over a period of 10 years. All researchers are themselves enthusiastic runners, and two of them participate in marathons. The topic was near and dear to their hearts.

Research was conducted on white runners, so it is unclear if the findings -- listed below -- apply to black runners.
  • Only 56 percent of runners in the study reported wearing sunscreen. Most were unaware of the increased risk to their skin -- and even the running researchers report it is good to be reminded to wear the right gear and regularly use sunscreen
  • Many runners race with a lot of skin exposed. And sometimes training clothing covers different areas than racing clothing. Shoulders that are covered during training may be exposed during the long hours of a marathon. During triathlons, most wear a bathing suit for the duration of the event, leaving most skin susceptible to burning. Runners can lower their risk by training during morning and evening hours and wearing water-resistant sunscreen. They can wear clothing made of new fabrics that screen harmful ultraviolet rays.
  • It's possible that endurance athletes may have suppressed immune systems caused by repeated tissue damage, leaving them more vulnerable to skin cancer.
While some marathon runners take pride in a bronzed skin -- proof they are running in the elements -- researchers hope runners will consider the risk they face. In some races, volunteers offer to quickly apple sunscreen on athletes who don't want to lose precious seconds as they race for the finish line. It's a start.

Ultrasound technique detects benign or malignant breast disease

The ultrasound technique called elasticity imaging might be able to reduce the amount breast biopsies given to patients. It works almost like a regular ultrasound examination of the breast except it is much more sensitive. The technique gauges how much tissue moves when pushed to detect how soft or stiff the mass is in the breast.

The study that was done showed that all 17 of the imaging studies thought to be malignant were found to be malignant after a biopsy was done. It also identified 105 out of the 106 benign lumps in the breast. From this study it suggests that elasticity imaging is 100 percent sensitive and 99 percent specific.

This could turn out be another useful tool used along with mammography and breast MRI's to detect a cancerous lesion in the breast. I, however, will always want a lump biopsied since I know that is the only way to know 100 percent whether it is malignant or benign.

(Thanks to Patti Anastasi for the tip)

Clinical trial tests common virus to treat malignant brain tumors

Malignant glioma is the most common primary brain tumor. The outlook for patients with malignant glioma is poor. Median survival for patients with grade III glioma is three to five years and less than one year for the most aggressive form of malignant glioma called glioblastoma multiforme.

The virus or reovirus that the researchers are focusing on is a common virus in humans that inhabits the lungs and intestines. The researchers added that this virus is something that most humans have been exposed to by adulthood but demonstrates no illness or negative effects on us.

When the virus is exposed to the malignant glioma cells it appears to infect and kill the tumor cells. Dr. James M. Markert, M.D., professor and director of the division of neurosurgery at the University of Alabama at Birmingham (UAB) and lead investigator of the trial explains "Healthy, non-cancerous cells in our bodies have the ability to prevent the reovirus from replicating, so that even if we are infected with the virus we do not usually exhibit significant symptoms but brain tumor cells do not have that protection, due to a mutation in their DNA. The reovirus replicates, destroying the tumor cell, and the replicated virus goes in search of new tumor cells to infect". So not only will the main tumor be destroyed but the virus could potentially be effective against glioma cells that have begun to spread away from the primary tumor to other parts of the brain.

The phase one clinical trial will enroll fifteen patients that have recurrent malignant glioma. The patients will have a brain surgery procedure that infuses the reovirus through two catheters that are placed on the tumor mass.

The main purpose of this study is to determine whether the virus is safe to administer to humans. It has shown in previous studies to be well tolerated and not have any negative side effects. This research sounds very exciting to me since this disease is very hard to treat. I know too well, as my uncle was diagnosed with a brain tumor and died just over a year from diagnoses before he turned forty. This was in 1987. The prognosis since that time really hasn't changed for malignant glioma. I hope this is something that can give the patients diagnosed much more hope of a longer survival.

Sunday Seven: Seven super searches to make at Wikipedia

I have made on-line visits to Wikipedia many times -- mostly for information on cancer. And what I've found are endless resources, thoroughly-covered topics, and material that is easy to read and easy to understand. Wikipedia, a free on-line encyclopedia -- where readers can participate in editing and changing content -- offers information on just about any topic you can imagine. And here are seven stops you might make in pursuit of cancer-related material.

Continue reading Sunday Seven: Seven super searches to make at Wikipedia

Staying out of sun saves lives, seeking sun steals lives

I wish I could reverse the damage I've already done to my skin after too much time spent in the scorching sun, in search of a tan. It's seems unfair that a tan is so temporary -- yet its damage is everlasting. And it seems crazy that so many people are still searching for a tan -- when it has become so clear that is it so harmful.

As many as 60,000 people a year die from too much sun -- mostly from malignant skin cancer -- according to the World Health Organization (WHO). About 48,000 deaths are caused by malignant melanomas, and 12,000 deaths are caused by other kinds of skin cancer. And 90 percent of these cancers are caused by ultraviolet light from the sun. Cancer is not the only side effect of sun exposure, though -- serious sunburn, wrinkling, eye cataracts, growths on the flesh of the eye, cold sores, and other illness can result from the sun.

We all need some sun -- the vitamin D that is produced in the body by the sun helps to prevent disease and immune disorders. But too much is dangerous and sometimes deadly. Yet almost all ill effects from the sun can be prevented. And the WHO has released a report that advises people to seek shade, to use sunscreen with an SPF of at least 15, and to stay out of tanning salons. The report operates under the premise that sunscreens be used not to prolong sun exposure but to protect the skin when exposure is unavoidable.

Breast cancer surgery during your lunch break

The UK's Daily Mail has published an incredible news story featuring a surgical procedure that cuts out tumors so quickly that it allows women to undergo breast surgery to remove breast lumps during their lunch break.

According to an explanation of how this works, in a procedure that lasts at the longest 30 minutes -- using a machine called Soros -- a small incision is made (that heals quickly and leaves no scar); the lump is sliced up into tiny pieces and vacuumed out of the body; and the woman has time left over to presumably have lunch.

This high-tech procedure is currently in clinical trials at the Princess Grace Hospital in London, and is expected to be used in the surgical removal of both benign and malignant tumors up to three centimeters in size. For a detailed step-by-step description, read Breast cancer surgery in your lunch break.

Pets: dog breast cancer survivorship story

Spotted Calamity Jane, my Dalmatian, was 3 1/2-years-old when she was determined to have breast cancer. I spotted this when checking her breasts after she was near completion of breast feeding her litter of 11 pups. At that time my vet was not concerned that the little marble sized lump would turn out to be cancer thinking it was probably where a pup had bit her harder than normal while nursing.

I had already made the decision to have Cally spayed after this one and only litter, so I gave the go ahead to have my vet remove the lump in her breast and biopsy it for safety.  We were all shocked to find out the results from the tumor biopsy was indeed cancer. I questioned whether chemo or any other kind of treatment was necessary and my vet felt like all of the lump had been removed and that there should not be any alarm for it to grow or spread.

Continue reading Pets: dog breast cancer survivorship story

Cancer Fundraisers
 (0)
Cancer events (141)
Pink products (63)
Celebrities
Celebrity cancer diagnosis (73)
Celebrity fundraisers (83)
Celebrity in memoriam (75)
Celebrity news (173)
Celebrity spokesperson (46)
Features
Form and Function (7)
Today, I Am Grateful (10)
Worthy Wisdom (21)
RetroReview (6)
Saturday Six (4)
Sunday Seven (64)
Survivor Spotlight (40)
Cancer by the Numbers (17)
Recipe Healthy Living (52)
Healing Attitude Almanac (6)
Thought for the Day (148)
Media
Blogs (144)
Books (109)
Magazines (51)
Movies (21)
Products (154)
Services (116)
Sports (20)
Television (101)
Video games (4)
Meet the Bloggers
Bloggers (13)
Jacki Donaldson (2)
Kristina Collins (1)
Diane Rixon (1)
Nine DeJanvier (1)
Chris Sparling (1)
Allie Beatty (1)
Dalene Entenmann (1)
News
Daily news (684)
Events (85)
Fundraisers (169)
Opinion (170)
Politics (145)
Research (799)
Prevention
Cancer prevention foods (170)
Diets (213)
Environment (115)
Exercise (94)
Non-toxic alternatives (35)
Nutrition (131)
Obesity (52)
Smoking (101)
Stress Reduction (91)
Vitamins and nutrients (90)
Treatment
Alternative Therapies (411)
Cancer Caregivers (71)
Cancer Pre-vivors (21)
Cancer Survivors (469)
Chemotherapy (495)
Clinical Trials (160)
Drug (497)
Hospice (18)
Prevention (1327)
Radiation (77)
Stem Cell (25)
Surgery (40)
Types of Cancer
 (0)
All Cancers (820)
Anal cancer (2)
Animal (18)
Bladder Cancer (39)
Blood Cancer (18)
Bone Cancer (15)
Brain Cancer (106)
Breast Cancer (1324)
Cervical Cancer (72)
Childhood Cancers (204)
Colon and Rectal Cancer (235)
Endometrial Cancer (25)
Esophageal Cancer (35)
Eye Cancer (6)
Gallbladder Cancer (2)
Gastric cancer (5)
Germ Cell Tumors (1)
Head and Neck cancer (13)
Hodgkin's Lymphoma (55)
Kidney Cancer (56)
Leukemia (145)
Liver Cancer (50)
Lung Cancer (273)
Melanoma (105)
Mouth Cancer (42)
Multiple Myeloma (13)
Neuroblastoma (1)
Non-Hodgkins Lymphoma (56)
Oral Cancer (16)
Ovarian Cancer (154)
Pancreatic Cancer (78)
Pet Cancers (11)
Pregnancy and cancer (6)
Prostate Cancer (233)
Rectal Cancer (3)
Sarcoma (8)
Skin Cancer (153)
Stomach Cancer (28)
Teen Cancers (26)
Testicular Cancer (17)
Throat Cancer (20)
Thymic Cancer (0)
Thyroid Cancer (49)
Tissue Cancers (1)
Tongue Cancer (3)
Unknown Primary (2)
Uterine Cancer (9)
Womb Cancer (1)
Young Adult Cancers (104)

RESOURCES

RSS NEWSFEEDS

Powered by Blogsmith

Other Weblogs Inc. Network blogs you might be interested in: