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Posts with tag markers

Thought for the Day: Something to bead about

Breast cancer survivor Linda Griggs offers a wide variety of hands-on healing products for other survivors -- like an inner child notebook with markers for journaling and expressing emotions, a wooden box with instructions on how to create a healing shrine, a non-fiction account of her own cancer journey, and so much more. Griggs, who also teaches workshops and speaks out on cancer as a hero's quest, is now onto something new. She's stringing beads.

Think about this:

"After helping a young breast cancer survivor make a "power necklace" to help pump her up before chemo, I realized perhaps other survivors might benefit from having their own empowering necklaces," Griggs says.

Griggs has begun making necklaces from natural stones associated with chakras she believes are most relevant to survivors. The root chakra, for example is connected with survival, the sacral chakra with emotional balance, the solar plexus chakra with personal power, the heart chakra with giving and receiving love, and the throat chakra with free expression.

Each necklace -- there are earring sets too -- come with an explanation of the stones and chakras involved and each has its own unique name. There is the
Amazon Warrior, the Wild Woman, and the Heart Light.

Think about a visit to Griggs' website when you have a moment. And bead all about the resources this one survivor has crafted for those wishing to transcend the depths of cancer.

Thought for the Day: On tonsils and breast cancer

I never thought I'd hear this one -- that women whose tonsils were removed during childhood may be at increased risk of developing pre-menopausal breast cancer. But sure enough, that's what researchers at the University of Buffalo are reporting.

Think about this:

Researchers say the association between tonsillectomies and breast cancer may be related to the loss of protective function when tonsils are removed. Also, tonsils can be markers for infection in childhood. Some infections cause inflammation which can contribute to cancer. When the tonsils are gone, markers are gone.

Other studies have linked tonsillectomies with an increased risk of Hodgkin's lymphoma, leukemia, and breast and prostate cancers. This study, reported at the 100th annual meeting of the American Association of Cancer Research, confirms the breast cancer connection -- but further study is still necessary.

Markers may predict risk of cancer recurrence in bladder cancer patients

Bladder cancer is diagnosed in 55,000 - 60,000 individuals annually in the United States. Patients whose cancer has spread to deeper tissues in the bladder and/or nearby lymph nodes may be treated with a radical cystectomy, the surgical removal of the bladder and nearby lymph nodes.

This approach may be able to cure the patient, however recurrences do occur. Researchers want to find out which patients may be more susceptible to a recurrence so that they can either monitor them more closely or treat them more aggressively to reduce the risk of recurrence.

An article was published in Lancet Oncology saying that markers may help predict the risk of cancer recurrences in patients who are treated with a radical cystectomy. Researchers from Texas and Canada conducted a clinical study to evaluate markers found in the the tissue samples taken after surgery. The markers tested included the expression of Bcl-2, caspase-3, P53, and survivin.

The study found that those patients that had an altered expression of Bcl-2, caspase-3, P533 and survivin were associated with over four times the risk of cancer recurrence. Also, the altered expression of all of these bio-markers was associated with nearly seven times the risk of death from cancer.

The researchers conclude that these findings support other studies that show these bio-markers can help predict who will remain cancer free. They look at this as moving forward towards more individualized treatments for the patients.

It did not say in the article whether using this test after the surgery would help them to determine if chemotherapy or radiation would be something that could reduce the risk of recurrence if the markers would show a high risk category of recurrence. I think this these studies are great but we need to be moving forward to get the patients to benefit from this vital information.

Cancer survivor's kit helps others keep on living

Survivorship is the new cancer buzz word -- and what an important word it is. Once left to each individual to define, manage, and transcend, survivorship is now recognized as a distinct phase of cancer recovery -- just as important, and maybe even more so, than diagnosis and treatment.

Linda Griggs, a 13-year breast cancer survivor, clearly remembers the day her chemotherapy ended. With her therapy complete, her hair growing back, and her medical team sending her off to have a nice life, she thought she'd be fine. But she wasn't.

Three months after her last dose of chemotherapy, Griggs was depressed, consumed with worry about how her cancer might come back. And she realized that the end of treatment is not really the end. It's just the beginning.

Griggs told her doctor about her anxiety, about how she was just trying to make it to her next three-month-check up. When her doctor told her, "that's not living," something clicked for Griggs who instantly decided to start living -- really living.

Surviving is about self-nurturing, says Griggs, who has created a kit to help others survive cancer. On her website, she writes that there are a couple of other breast cancer survivor kits out there -- containing tissues, herbal teas, meditation tapes, medical appointment books, and breast cancer resource materials.

"This is not that," she says of her kit that focuses on the emotional upheaval cancer creates.

Griggs' kit is full of hands-on creative materials -- like an inner child notebook, complete with magic markers for journaling and expressing emotions. If you're angry, you can write down angry thoughts. If you're sad, write what makes you sad. Save the pages, tear them up, burn them, do what you wish -- but allow your emotions to flow, Griggs says.

The kit also includes a wooden box with instructions on how to create a healing shrine, a copy of Griggs' non-fiction account of the first five years of her cancer journey, and so much more.

Griggs, who also teaches healing workshops, guides others to understand cancer as a hero's quest. She says when something happens to us -- death, divorce, disease -- we are receiving a call to adventure. All bet's are off. We must start fresh, gather our spirit guides, collect ourselves, dive into the underworld, overcome, and then emerge full of wisdom of growth.

Griggs has emerged -- full of her own wisdom and growth. She is a hero -- on a quest to help others survive a disease that threw her way off track for way too long.

Merck, Moffitt Cancer Center partner to personalize treatment

Tampa's H. Lee Moffitt Cancer Center & Research Institute, the only comprehensive cancer center in Florida, has just partnered with Merck & Co., one of the world's largest drug companies, to develop personalized cancer treatments using a patient's genetic profile.

The two powerhouse entities will form a for-profit company called M2Gen on donated land near the University of South Florida. And in the span of just a few years, researchers plan to compile a database of tumor tissue and other medical information to determine why some patients respond to treatment while others do not. The database could house information on more than 30,000 patients within five years and will enable researchers to identify biological markers that could help doctors choose the most effective treatment based on the genetic make-up of each patient's tumor.

Blind treatment -- where everyone receives the same thing -- will be a thing of the past as tailor-made therapies replace the one-size-fits-all approach.

Florida Governor Jeb Bush says of the partnership that will create more than 170 high-paying jobs, "Man, I don't know if you can think of a better Christmas present than that."

Tumor markers predict cancer growth -- sometimes

Cancer cells sometimes secrete specialized proteins into the bloodstream that serve as indicators of tumor growth. These tumor markers are often distinctly associated with a particular type of cancer. Like prostate cancer.

The most well-known tumor marker today is the PSA -- the prostate-specific antigen. PSA is a highly specific protein that is secreted only by cells of the prostate gland. It is one of the most widely used -- and the only widely accepted -- screening test for cancer.

There's also the tumor marker CA-125, used in the diagnosis of ovarian cancer and in the monitoring of response to treatment for the same disease. There's CEA for colon cancer, CA-19-9 for pancreatic cancer, AFP for liver and testicular cancer, beta-HCG for testicular cancer, and CA 15-3 for breast cancer. And research is under way on newer, more useful tumor markers. This is a good thing -- because some tumor markers are not specific enough or sensitive enough to accurately predict tumor growth.

This is why my oncologist does not recommend I enter the world of tumor markers, despite my status as a breast cancer survivor. He suggests I rely simply on how I feel for monitoring my chances for cancer recurrence. If I experience any worrisome symptoms, he will be the first to wage an all-out assessment of my health. But without symptoms, tumor markers are not likely to help me at all.

A peek at my breast cancer tumor markers would likely be hazy, inconclusive, and not all that helpful. Examination of tumor markers can lead to false positives. It can lead to expensive and often unnecessary follow-up testing. It can lead to worry and panic and even alarm if the numbers are not in the hoped-for range.

Although an abnormal tumor marker level may suggest cancer, this alone is typically not enough to diagnose the disease. Measurements of tumor markers are usually combined with other tests, such as a biopsy, to confirm cancer. So what would I do with an abnormal number and nothing suspicious to biopsy? I would worry. I would panic. Perhaps unnecessarily.

My doctor suggests I refrain from a wild cancer chase. And I am happy with his suggestion. Between my own awareness, follow-up oncology appointments, mammograms, annual OB/GYN check-ups, and more, I am confident any health issues that come my way will be detected early -- and can be resolved in good time. I have no need for confusing tumor marker details. Unless they are conclusively recommended, I will survive without them. More important, I will survive without worry.

Cancer by the Numbers: Pancreatic Cancer

My mom's best friend died from pancreatic cancer just three months after her diagnosis with the disease. One of my co-workers lost her mother to the same disease just weeks after diagnosis. Another co-worker's husband lost his battle with pancreatic cancer after a 15-month all-out fight. And a family friend has somehow been surviving this deadly disease for years now. He's the exception, defying the odds rarely in favor of long-term survival.

About 33,730 people will be diagnosed with pancreatic cancer in 2006. Many of them -- 32,300 -- will die from the disease that is rarely caught early. Pancreatic cancer is the fifth leading cause of cancer death in the United States.

Continue reading Cancer by the Numbers: Pancreatic Cancer

Visit with oncologist prompts same old routine

I will visit my oncologist on Monday for my every-three-month check-up. It's the recurring appointment that will appear on my calendar until I hit the five-year-survival milestone. I am three years away.

It's the appointment that consumes at least half of my day due to endless waiting -- waiting for a parking spot, waiting in the lobby, waiting in the exam room, waiting to pay. It's the appointment that officially begins with the drawing of my blood for lab work, continues with a check of my vitals, proceeds with a history review and physical exam with a medical student. It's the appointment that brings me face to face with the man who prescribed my treatment, the man who offers me strategies for living beyond treatment, the man who helps keep me alive. My oncologist.

And so I am preparing for this visit in the same exact way as I always do. I set aside a large chunk of time for this time-consuming extravaganza. I think a lot about the lab work and wonder if something suspicious will surface. I think a lot about the physical exam and wonder if an enlarged lymph node or mass in my breast will be discovered. And I think a lot about what I want to ask -- because this is my only very own allotted time for unraveling the mysteries of cancer with the man who knows the topic like no one else I know.

On Monday, I will ask a few questions. I will ask about tumor markers, about why I am not tested for these indicators of tumor growth, a standard option for my co-writer and co-cancer survivor Kristina Collins. I will ask about Zoloft, about how long I should continue taking this anti-depressant and how to best wean myself from this drug when the time comes. I will ask about the flu shot, about whether or not I can get one during this same appointment.

And that's all. For now. Until three more months pass and my calendar tells me it's time to return for this recurring appointment that takes me closer to the five-year mark.

Blood tests to check for cancer recurrence: The waiting is over

Normal! That was the first word out of my oncologist's mouth when he called me last night. I was wondering if he would decide to call me even if everything was fine. Since I haven't gotten the tumor markers done in three years, I figure the man had to be curious.

I was thinking to myself last night before he called that I wanted him to care, not so much about what happens to me, but care about getting me the results as soon as possible. I know I'm not his only patient and he is a busy man but I don't want to be just a number either, someone easily forgotten when I leave the office. My husband says that is definitely not the case because I have made myself known in that office. Hmmm.. what could he possibly mean by that? I ask a lot of questions, show up when I don't have appointments, refuse to do blood work, yell at the callous receptionist in front of the whole waiting room, cry a lot..etc.

I'm lucky that I have the oncologist that I do. I feel like he does know me and that is so important.

Blood tests to check for cancer recurrence: The waiting game begins

Not only did I get the tumor markers to check for breast cancer recurrence but I figured I would really go nuts and have them do the ovarian cancer tumor marker too. I figured if I'm going to be worrying anyhow I might as well worry about everything. Of course I'm also thinking about the other blood tests they will be doing, especially the liver enzymes.

Yesterday I showed up at my oncologist's office without an appointment. I knew that I wouldn't need to see my oncologist to get a port flush and blood taken, however when he saw that I was there he wanted to see me. He immediately thought I had some sort of pain somewhere for me to be all of a sudden wanting tumor markers that I usually refuse to get. I do not have any pain or reason for getting these tests other than the fact that mentally I need to do this for myself.

This is hard, very hard. I'm scared that something is going to show up. I keep telling myself that knowledge is power and that if they do find something wrong that I will be getting on top of the problem before it gets worse. At this point I'm not sure if I will be calling my doctors office all day in a panic on Tuesday or if I'll just wait and see if my oncologist calls me.

Breathe in breathe out, breathe in breathe out...

Anxiety and blood tests to check for recurrence of breast cancer

Today might be the day. I think I finally am going to let my oncologist do tumor markers. I'm scared. I haven't had tumor markers done in about three years. After my treatment ended four years ago I let my doctor do the tumor markers for one year. I thought I was going to go crazy -- living my life in three month increments. I would say to myself, "Well, I can't plan that because what if my tumor markers show something in three months."

Testing and the anxiety that goes with it is something that all cancer survivors have to deal with. I just decided not to deal with it at the time because I didn't feel like I was living and it was ruining my quality of life. When I first started writing for The Cancer Blog one of my first posts was about how I felt about tumor markers. It's not that I don't feel that way anymore but I do feel a new strength that I can deal with whatever happens.

I still have my port in. It will be five years in December since I have been diagnosed with breast cancer. I need to get this port out and move on with my life. I feel stuck. I need to know if I really am okay and if not I need to fight what is going on inside of me. I can't hide from it. I haven't told anyone I was going to do this but woke up this morning and I felt it was something I needed to do -- today.

I wonder if I will chicken out! I hope not.

Tumor marker testing after breast cancer treatment

There is much debate about follow-up testing after breast cancer treatment. Some oncologists check the blood for tumor markers routinely while other oncologists choose not to use them. One popular marker that is used to detect early breast cancer recurrence is called CA 27.29.

Tumor markers caused me severe anxiety. I guess that would come with the territory of cancer. Get diagnosed with breast cancer, go through months and months of treatment and then have to get tests to see if the cancer has returned. It never ends.

I put a stop to it myself. For me this came down to a quality of life issue. For a year after my treatment was over for breast cancer I would get the tumor markers done every three months. I was living my life focused on these numbers. Am I in normal range?! What agony waiting for the results!

Continue reading Tumor marker testing after breast cancer treatment

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