Canadian researcher Evangelos Michelakis, associate professor of medicine at the University of Alberta in Edmonton, has stumbled upon something quite remarkable -- a potentially new anti-cancer agent called dichloroacetate, or DCA.

DCA is nothing new -- it's long been used for treatment of rare metabolic disorders -- but using it to fight cancer puts an entirely new spin on the potential of this drug.

"This is one of the most exciting results I've ever had," Michelakis said. "But I can't be overenthusiastic until it works on a human."

Michelakis and his colleagues have successfully used DCA to shrink human lung, breast, and brain tumors in both lab rats and test tubes. And while this type of research may not ordinarily generate a lot of excitement, this specific study is creating a buzz because DCA has been safely used in humans for decades, without adverse side effects.

"One of the big concerns about drugs is that they can harm people but we already know this drug is safe," Michelakis says. "It doesn't even affect normal cells."

One of the fundamental premises of cancer biology is that mitochondria -- the energy producing units of cells -- are permanently damaged by cancer. What DCA does is revive the mitochondrial function, encouraging the death of cancer cells.

The overwhelming hope is that DCA will move right to human testing. But the overwhelming fear is that it will not -- because of economic reasons. There is no longer a patent on DCA so it is not owned by any one company. With little chance of one group making a large profit, there may be no incentive for pharmaceutical companies to invest in research.

Sadly, this drug -- that appears to work remarkably well -- may never benefit cancer patients. All because no one stands to make billions of dollars from it.

Calorie counting may be a bit tedious for some -- like me -- but for others, it may be just the ticket for the management of weight and overall health.

Charles Stuart Platkin, author of the new book The Diet Detective's Count Down, takes calorie counting one step further and offers the exercise equivalent of a nutritional label.

His 341-page book offers charts that detail the number of calories, fats, and carbohydrates in more than 7,500 foods and drinks and then translates these details into what it takes, in terms of minutes, to burn the calories with walking, running, biking, swimming, yoga, or dance.

Platkin, a syndicated nutrition and fitness columnist, says he is not trying to encourage people to count every calorie consumed in a day and to exercise until each calorie melts away. His goal is to help those who exceed their daily calorie budget -- the number of calories they can eat each day without gaining weight.

The Count Down goes like this -- you consume one martini at your New Year's celebration, pushing you beyond your allotted calories for the day. All you have to do is walk it off the next day in a mere 71 minutes. Or you can run it off in just 39 minutes. If a single cracker with one slice of Genoa salami and cheese tempts your palate, go for it -- then plunge into a 55-minute yoga class.

Before taking a stab at the diet detective's approach, there are several considerations to take into account. First, the book is based on a 155-pound person. A person carrying more weight would burn more calories per minute, and a person carrying less weight would burn less. Second, a person's basal metabolic rate (BMR) must be calculated -- Platkin offers formulas for this task -- so it's clear how much activity output is required by each person. And third, the exercise equivalents are based on scientifically researched metabolic equivalent tables that try to measure what is being burned versus a person's resting metabolic rate. So this is not just a crazy gimmick. It's science -- with a touch of personal perspective too.

Platkin, clinically obese for most of his life, lost 50 pounds a few years ago and came to realize that people just don't know what a calorie is. He wishes the U.S. Federal Drug Administration (FDA) would include exercise recommendations on food labels and says, "I think that we are so confused in general as a population as to what's healthy and what's not, we confuse the term healthy with low-calorie. Sometimes they don't mesh. There's so much confusion out there that I think that it needs to be more defined. We need to have some sort of reference points so that people can make decisions before they consume."

Until the FDA delivers on Platkin's wish, he is taking matters into his own hands for those who choose to borrow from his wisdom.

Some of his wisdom includes eating calorie bargains (air-popped popcorn) instead of calorie rip-offs (potato chips) and substituting mustard for mayonnaise on a burger -- it will save 2,000 calories per month for someone who eats fast food three times per week.

Platkin's hope is simple -- he wants people to ask themselves whether certain foods are worth the cost. Is it worth a 54-minute run to burn the 510 calories in a McDonald's Quarter Pounder with Cheese? How about a 144-minute walk to rid yourself of a Subway six-inch Meatball Marinara sandwich?

It's a worthy hope, I think -- although this method is still a bit tedious for me. I think I will stick with my own formula -- eating moderate portions of what I enjoy and intensely exercising several times per week. I don't need to know how many calories I am consuming. I don't even need to know how much I weigh. As long as my clothes fit and my fitness routine keeps me sweating, I'll be a happy girl.

At Reuters Health, Metabolic syndrome predicts breast cancer relapse features news about the results of a study that evaluated 110 breast cancer survivors and found 8 of the 16 women who were diagnosed with metabolic syndrome developed breast cancer recurrences. A total of 32 women out of the 110 women suffered recurrence. This has led researchers to estimate that breast cancer survivors with metabolic syndrome were three times more likely to have a recurrence of breast cancer as women without the syndrome.

Metabolic syndrome is a combination that can include high cholesterol, obesity, high blood sugar and high blood pressure. Traditionally thought to be warning signs or symptoms of diabetes and heart disease, researchers believe that the syndrome can also be something to watch for in breast cancer survivors.

All of the characteristics of metabolic syndrome can often be controlled with a proper diet, active lifestyle and medication. Before this study came out, there have been anecdotal conversations in the breast cancer community in regards to following a healthy balanced diet and lifestyle recommended for people with diabetes and heart disease. For more information about dietary and lifestyle recommendations for diabetes and heart disease, visit the American Diabetes Association or the American Heart Association.

In my every day average life, it is not in a language I speak. In my opinion, the news release is all very technical and scientifically worded -- basically a snoozefest for the pedestrian reader -- but it's interesting because of the common links found in the function of insulin, hormones, diabetes, obesity and cancer. Ludwig Institute for Cancer Research UCL Branch and the UCL Centre for Diabetes & Endocrinology researchers found the commonality by studying the function of the molecule p110 alpha, the flag-ship molecule of the eight member PI3K family, which is one of the most frequently activated pathways in cancer. According to the researchers, this study yielded information that could affect millions of people with metabolic disorders and cancer. The rest of the news release is found here.

The reason I am mentioning it at all, is the research reminds me of information I found four years ago when I read The Breast Cancer Prevention Diet by Dr. Bob Arnot. Dr. Arnot, NBC News chief medical correspondent, began researching breast cancer prevention after his mother-in-law was diagnosed with breast cancer. His book was the first I came across that suggested insulin level was something to pay attention to for women interested in breast cancer prevention, and he outlined the reasons why a low glycemic diet was important for cancer prevention. Dr. Arnot's book includes a great deal of information about nutrition and diet, and I would recommend it to any woman newly-diagnosed with breast cancer and women interested in reducing their breast cancer risks.

As a cancer survivor, I am interested in any information that might aid in my survival. Even if you have not been diagnosed with cancer, or diabetes, or one of the many metabolic diseases that people suffer, it is common sense that maintaining steady insulin levels is important to long-term good health. Without ever knowing or understanding a thing about the molecule p110 alpha, we can benefit by learning about how foods affect our health in helping prevent the onset of many diseases. Sometimes I get the feeling disease, any disease, is the result of a complex falling domino-effect of causes. I am not sure how many dominos we can prevent from collapsing into each other, but I am fairly certain we can make a difference in how fast some of them fall.