The two drugs Velcade (bortezomib) and Revlimid (lenalidomide) are designed to treat the bone marrow cancer called multiple myeloma. A Phase I clinical trial has shown that the drugs may be more effective together than when used individually.

The trial was led by researchers at the Dana-Farber Cancer Institute in Boston. It included 38 patients who had their cancer recur despite other therapies. The patients were divided into groups that received successively higher doses of Velcade and Revlimid. Some patients also received the drug dexamethasone which can add to the anticancer effects of these two drugs.

Fifty-eight percent has responded to the combined treatment, six percent achieved complete remission. Researcher Dr. Paul Richardson said in a prepared statement "We are hopeful that this combination will prove to be a key therapeutic backbone in improving outcomes for our patients, both early and later in the course".

Multiple pregnancies for women who carry the inherited mutations in BRCA1 or BRCA2 genes appears to reduce the risk of developing breast cancer, according to researchers from the German Cancer Research Center. The International BRCA1/2 Carrier Cohort Study set out to examine if the same breast cancer protective factors of multiple births and breastfeeding provided to women without the genetic mutations extended to women with the BRCA1 or BRCA2 genes. 

According to the study, women with one child have the same breast cancer risk as childless women. The risk of developing breast cancer after age 40 was lowered by 14 percent with every child. Interestingly, women with a BRCA2 mutation had twice the cancer risk if they had given birth to their first child after age 20 compared to those who had become mothers before age 20. For carriers of BRCA1 mutations, it was the exact opposite. The risk of getting breast cancer was lower in women who had given birth to their first child after age 30. The only thing about research -- it is only correct until the next research study. I only say this because I hear over and over from women who are surprised by a breast cancer diagnosis when they did not have any of the risk factors or they fit the profile of a woman with reduced risk. If you have the inherited BRCA1 or BRCA2 genes, the study results are a generalization, and your individual situation might differ. I would not sit here and read into this study that you are going to get breast cancer because you only gave birth to one child -- or that you didn't have children at the optimum age.