Note: The contents of this blog are for informational purposes only and should not be construed as medical advice or substitute for professional care. For medical emergencies, dial 911!
Wouldn't it be great if we could receive full-body scans every year to check for early signs of cancer and other disease? Even if possible and affordable -- right now, scans cost about $900 -- it still wouldn't be such a great idea.
Full-body scans often result in false alarms. People with harmless abnormalities may end up facing more tests, more risks, and more worry in order to rule out illness. The scan itself can present health hazards too. It exposes patients to more radiation than a chest X-ray and could slightly increase the risk of cancer, especially for those scanned every year.
How do we know, then, if something has gone awry in our bodies? Well, we can do our self-exams -- breast exams, testicular exams, skin exams -- and we can report for annual check-ups. We can respond to symptoms we experience -- if headaches are bothersome and persistent, your doctor may prescribe a head scan -- and we can pursue tests and screening that we really need for cancer prevention and early detection. Here are just a few:
Author Leah Hager Cohen says her blog is inspired by her mother, for at least two reasons. One: it is because of her mom that she's a writer. "She has seen me for a writer my whole life, ever since I could make up stories and dictate them to her," says Cohen. Two: her mom is fighting ovarian cancer, has been since April 2006 when she was 62. Cohen's blog -- Love As a Found Object -- is for her mom and about her mom. It is quite a blog.
In an entry written in September 2006, Cohen shares:
My mother is perhaps the most energetic person I know, and my children, who collectively run a close second, have grown accustomed to having her set the pace when she is around. She's the one who persuaded me, six years ago, that the kids and I did not need a dining room nearly so much as we needed a "project room." She usually arrives for visits bearing the raw materials and mental blueprint for some art or engineering project into which she and the kids then plunge together. Even though we've all had months to get used to her cancer, her tiredness still seems strange, as does the chemo-haze from which she regards us more quietly than is her wont. She seems almost an imposter in this muffled state, so accustomed are we to having her lead us on capers and jaunts through real and metaphorical woods.
Losing the ability to have children would for many be the ultimate tragedy in a young person's battle with cancer. So here's some promising news: A transplant of ovarian tissue between sisters has shown to be successful, and the eggs have even been fertilized, though complications have caused a loss of the potential the pregnancies.
The transplantation of ovarian tissue between Teresa Alvaro and her sister, Sandra, is promising though the sisters were fortunate to share the same human leukocyte antigen (HLA), meaning that they wouldn't reject tissue from the other's body. Teresa lost ovarian function due to treatment of a blood disorder when she was 20, and preferred transplantation of ovarian tissue to donation of eggs, because she felt it was more natural.
Femara (letrozole) provides both anticancer responses and disease stabilization in a significant number of patients with recurrent, estrogen receptor positive ovarian cancer. The results of the study were published in Clinical Cancer Research.
Femara blocks levels of estrogen in the body, ultimately reducing or preventing growth of estrogen positive cancer cells. Femara has been demonstrated to be effective for estrogen positive breast cancer, but has not yet had a clear influence in women with ovarian cancer.
Forty two patients were part of a clinical trial to evaluate the effectiveness of Femara. At three months, 42 percent of patients achieved disease stabilization and 9 percent achieved a regression of their disease. At over six months, 26 percent of patients still did not have progression of their disease measured by CA125 levels in the blood.
The researchers concluded that Femara may provide an effective and well tolerated treatment alternative for patients with recurrent, estrogen positive ovarian cancer.
High-profile television and newspaper gosspip columnist Claudia Cohen, most recently a regular correspondent covering entertainment for the syndicated talk show Live With Regis and Kelly, died Friday of ovarian cancer. She was 56.
Known for her aggressive pursuit of celebrity news and her public divorce from billionaire businessman Ronald O. Perelman, Cohen first hit the spotlight in the late 1970s as a reporter and editor for Page Six of The New York Post. She went on to write a gossip column titled I, Claudia for The Daily News of New York, report for Live with Regis and Kathie Lee, and dish celebrity dirt for ABC's The Morning Show.
Cohen is survived by her parents, a brother, and a daughter.
Ovarian cancer is hard to detect and is usually found in the advanced stages. It is the most deadly of all gynecological cancers. Transvaginal sonography (TVS) screening has been associated with detecting ovarian cancer at earlier stages of the disease.
TVS is a procedure used to examine the vagina, uterus, fallopian tubes, ovaries, and bladder. An instrument is inserted into the vagina that causes sound waves to bounce off organs inside the pelvis. These sound waves create echoes that are sent to a computer, which creates a picture called a sonogram. The test is also known as a transvaginal ultrasound.
The researchers' findings appear in the May issue of Cancer. In the study, colleagues assessed the value of annual TVS screenings in over 25,000 women. Participants had to be at least 50 years of age with no cancer symptoms or at least 25 years of age with a family history of ovarian cancer.
Drugs currently in trials for obesity and diabetes may soon be fast-tracked for use in the fight against breast cancer. Typically, it takes many years to research and develop new drugs. But these already-developed drugs, if successful, could reach the market much quicker.
The drugs, believed to work by blocking the enzyme PTP1B, could help breast cancer patients because the enzyme is found in high levels in about 40 percent of these patients.
Studies on mice show blocking production of the enzyme significantly slowed tumor development. In some cases, it stopped the spread of the cancer and it might even stop some tumors from forming.
Its back in the news again saying that so far the studies have shown Phenoxodiol to have an excellent safety profile, with few patients experiencing side effects.
New studies are also being done to help explain the mechanism by which Phenoxodiol induces cancer cell death. This drug interacts with a tumor specific protein and blocks cancerous cells from dividing, causing it to die.
Phenoxodiol also has showed some promise of restoring drug sensitivity in patients that have become resistant to treatment. The OVATURE trial that was discussed in my November post should have results out within 18 months.
Many cases of ovarian cancer are diagnosed at advanced stages, its one of the gynecological cancers that is hard to diagnose in the early stages of the disease. Ovarian cancer needs to be treated correctly from the get -go for the best chance of survival.
It seems that some women are not receiving appropriate surgery in the United States based on an article in Journal Watch by Andrew M. Kaunitz MD.
A study found that out of 10,000 women diagnosed with ovarian cancer from 1999 to 2002, only forty two percent underwent surgery at teaching hospitals. Almost half of the patients in the study were operated on by surgeons who performed fewer than 10 ovarian cancer surgeries each year. Scarier yet, the study showed that about 25 percent of these women underwent surgery by very-low-volume surgeons -- less than one annually.
Dr. Kaunitz advice is to seek out a gynecological oncologist to get comprehensive care that is needed.
Don't be afraid to ask a surgeon -- How many times have you performed this surgery?
A high intake of vitamin C has been shown to reduce the risks for virtually all forms of cancer, including leukemia, lymphoma, and lung, colorectal, and pancreatic cancers as well as sex hormone related cancers like breast, prostate, cervix, and ovarian cancers. Vitamin C is your body's first and most effective line of antioxidant protection. Vitamin C protects cell structures like DNA from damage and it helps the body deal with environmental pollution and toxic chemicals. Vitamin C enhances immune function, and it inhibits the formation of cancer causing compounds in the body (such as the nitrosamines, chemicals produced when the body digests processed meats containing nitrates).
Dr. Douglas Brodie states in the book, Alternative Medicine Definitive Guide to Cancer, "Each one of us produces several hundred thousand cancer cells every day of our lives. Whether we develop clinical cancer or not depends upon the ability of our immune systems to destroy these cancer cells. That's because cancer thrives in the presence of a deficient immune system."
Here is a list of foods high in vitamin C. Adding these foods to your daily diet will help boost your immune system which will aid you in fighting off many diseases as well as cancer. Fruits and vegetables are both high in Vitamin C. The highest are papaya, raw red and green peppers, oranges, cantaloupe, broccoli, cauliflower, strawberries, Brussels sprouts, baked potato, cabbage, green peas, kiwi fruit, and kale.
There are a few good vitamin C supplements on the market but one that I particularly am using at present to super charge my immune system is Emergen-C Super Energy Booster which has 1,000mg of vitamin C along with vitamin B and 32 mineral complexes.
It is not new to hear that soy and broccoli have been linked to lowering cancer rates, if they are a part of your daily diet. California researchers think they understand what the effect of these veggies have on the cancer cell.
The researchers are convinced that there is a biological mechanism behind the protective effect. It is explained in the article that a compound resulting from the digestion of cruciferous vegetables, and genistein, an isofavone in soy, reduce the two proteins needed for breast and ovarian cancer to spread.
Cancer cells can be drawn to metastasize by having high levels of a surface recepter on the cell. The organs in which the cancer spreads also secrete high levels of a different receptor that binds to the cancer cell's receptor. This attraction stimulates the invasive properties of cancer cells and acts like a homing device, drawing the cancer cells to organs like the liver or brain.
The study found that when cancer cells were treated with high levels of compounds found in broccoli and soy, the drawing mechanism to the organs was reduced by 80 percent compared to untreated cells.
Dr. Alan Kristal, associate head of the cancer prevention program at Fred Hutchinson Cancer Research Center says "This is an entirely unique mechanism...Preventing the invasion and metastasis of cancer cells is crucial"
More studies are needed but the research suggests that this attraction can play a role in the development of more than 23 different types of cancer.
Results of two studies, sponsored by the Adjuvant Breast Cancer (ABC) Trials Collaborative Group, conclude that adding chemotherapy to the estrogen-blocking drug tamoxifen improves survival for those with early-stage breast cancer. The same studies reveal preventing the secretion of estrogen from the ovaries does not offer much benefit for most women.
Researchers studied 1991 patients, ages 28 to 81. All had received five years worth of treatment with tamoxifen therapy with or without standard chemotherapy. Some premenopausal women were also treated with ovarian removal (ablation) or suppression, a technique used to stop the glands from secreting hormones.
While early results, appearing in the Journal of the National Cancer Institute, fell short of statistical significance, chemotherapy still reduced the overall risk of death by 17 percent, mostly for women younger than 50 and especially for premenopausal women not treated with ovarian ablation or suppression.
Ovarian cancer is difficult to detect. There are no great screening tests to pick up on its presence in the body, and by the time symptoms appear, the disease has often progressed into an advanced stage. But a ray of light has recently emerged in the study of ovarian cancer -- and it could help in the prevention and early detection of this deadly disease.
Think about this, from the April 2007 issue of Woman's Day magazine:
Researchers at the University of Washington School of Medicine have identified a simple checklist of six symptoms associated with an increased risk of the disease and three of them -- if they occur at least 12 times per month and are present for less than one year -- were present 57 percent of the time in a study of women with early-stage disease.
And the three symptoms are: abdominal and pelvic pain, bloating and difficulty eating, and feeling full quickly.
If you experience these problems, especially if they are frequent or new, contact your doctor because identifying ovarian cancer quickly is key. In its early stages, the cure rate is 90 percent. But for advanced cancer, it's only 20 percent.
Not everyone buys into the power of pink when it comes to breast cancer.
Pink ribbons, pink teddy bears, pink hats, shirts, scarves, socks, purses, jewelry, magnets, and even cooking appliances have monopolized the breast cancer market. And some people just plain refuse to associate the disease with anything remotely sweet, soft, and soothing.
Think about this:
Annette`s Angels, founded in 2006 by the children of Annette Roberta, love and applaud the effectiveness of the flood of pink used to raise awareness about a disease that took Roberta after a 15-year battle.
But they refuse to embrace any color but black as they proceed to kick breast cancer in the butt. Black reflects their anger at breast cancer. And their power to fight it.
Annette's Angels are committed to fighting this terrible disease, and they invite us all to shop at their online store, where some items -- there's just no way around it really -- are pink. The angels will donate 50 percent of all profits toFORCE: Facing Our Risk of Cancer Empowered, the only resource of its kind for those facing genetic breast and ovarian cancers.
There's been much press lately about the cervical cancer vaccine, its merits, its implications, and the debate surrounding the issue of vaccinating young girls against the sexually transmitted virus HPV.
Enter a new vaccine -- the ovarian cancer vaccine.
Early clinical trial results are promising for this vaccine, intended to fight off ovarian cancer tumors with patients' own cells -- but without the toxicity of traditional chemotherapy.
Says Dr. Ed Staren of Cancer Treatment Centers of America, "We're able to identify the specific components of the tumor and target it for individual therapy for the patient."
Doctors would surgically remove a patient's tumor and then send it to a lab where tumor cells would be used to create a vaccine specifically for the patient.
A second round of clinical trials to study the effectiveness of this vaccine will begin this summer.