When I read something powerful -- a quote, a story, a reflection -- I write it down or cut it out or make a copy of it and drop it into a file folder I've titled inspiration. This file, among others, has been on many a moving van and has traveled with me all over the East coast, from city to city, house to house. And every once in a while, when I need a lift, this is my go-to file -- I go to it, pluck something out, and refresh my mind and spirit.

This file has been with me since at least 1997 -- the date on a photo-copied Ann Landers column I have sitting before me. It's 10 years old, but there's nothing dated about the words printed on this single sheet of paper. They are as touching and moving and relevant now as they were when I first read them. They may be even more meaningful today, because of the thread of cancer that is now woven throughout my days.

These are life lessons, offered by a publisher of the Mount Pleasant News in Iowa, for students about to graduate from high school. They go like this:

Dear Graduates:

There is the kind of education you get in school and the kind you get afterward. Both are important. Put them together, and you have wisdom. The trouble is, life is generally half over before you figure out what is going on.

Graduating seniors can save 25 years of trial, error, and hard knocks by memorizing the lessons of life listed below.

On the average, you learn about one big lesson per year after you leave high school. In really tough years, you learn two or three. Some years, you don't learn anything. After 40, you forget things and have to learn them again.

Some of this information is borrowed. Some is stolen. Some may even be original, but that's doubtful. It's pretty hard to be original in a world as old as this one.

25 Things You'll Need To Know After High School

1. Don't sweat the small stuff, and remember, most stuff is small.
2. The most boring word in any language is "I."
3. Nobody is indispensable, especially you.
4. Life is full of surprises. Just say "never" and you'll see.
5. People are more important than things.
6. Persistence will get you almost anything eventually.
7. Nobody can make you happy. Most folks are as happy as they make up their minds to be.
8. There's so much bad in the best of us and so much good in the worst of us that it doesn't behoove any of us to talk about the rest of us.
9. Live by what you trust, not by what you fear.
10. Character counts. Family matters.
11. Eating out with small children isn't worth it, even if someone else is paying.
12. If you wait to have kids until you can afford them, you probably never will.
13. Baby kittens don't begin to open their eyes for six weeks after birth. Men generally take 26 years.
14. The world would run a lot smoother if more men knew how to dance.
15. Television ruins more minds than drugs.
16. Sometimes there is more to gain in being wrong than right.
17. Life is so much simpler when you tell the truth.
18. People who do the world's real work don't usually wear neckties.
19. A good joke beats a pill for a lot of ailments.
20. There are no substitutes for fresh air, sunshine, and exercise.
21. A smile is the cheapest way to improve your looks, even if your teeth are crooked.
22. May you live life so there is standing room only at your funeral.
23. Mothers always know best, but sometimes fathers know too.
24. Forgive your friends and your enemies. You're all only human.
25. If you don't do anything else in life, love someone and let someone love you.

My gut hasn't always guided me through life's most difficult decisions and dilemmas. It wasn't until I felt a lump in my breast more than two years ago that my gut kicked into gear and told me something very important.

"It's cancer," my insides told me one week before the surgeon who did my biopsy called.

"It's cancer," the surgeon said. I didn't tell him, but I thought it: "I know."

I also knew prior to surgery that my cancer had not spread to my lymph nodes. My gut told me this too. It also told me the chemotherapy drug Taxol was not right for me -- since my cancer had not spread -- despite the urging of one oncologist that I accept this treatment. I would have gone on gut instinct alone in my rejection of this medication but another doctor weighed in and agreed with my gut, so I had solid backing on this decision.

Many have dismissed hunches like these and have written off those who believe in them as screwballs, says writer Chip Brown in the March 2007 issue of The Oprah Magazine. But as Brown shares after peering into the world of gut instinct, there are 100 million nerve cells in the gut. They run on autopilot, regulate digestion, play a critical role in the body's immune system, and control mood-altering neurotransmitters identical to those in the brain.

The gut is essentially a second brain. It was a "gut feeling" that led Fred Smith, founder of Federal Express, to begin exploring the possibilities of overnight delivery and Howard Schultz, founder of Starbucks, to begin mass marketing coffee. Wall Street professionals make millions on their gut feelings, sportscasters make startling predictions based on gut guidance, and entrepreneurs launch thriving businesses because of the inklings that rumble in their tummies.

You may or may not be a gut thinker yourself. But I've stumbled upon a gut exercise -- thanks to psychotherapist Nancy Napier --and I'd like for you to consider it the next time you find yourself stuck at a crossroads, unsure of where to turn. You never know, the direction you seek may be swirling around in your midsection, just waiting for a call to action.

Think about this:

You are wavering between two choices. Find yourself a quiet, serene place where there will be no disruptions. Now sit down. Take a moment to settle and focus on the issue you want to explore. Then choose one side. Think about this side and notice what happens in your gut. Do you feel a tightening and gripping or a softening and warming? Are the sensations pleasant or uncomfortable? Notice your thoughts. Are they positive or negative? Give yourself some time to feel your gut and your mind responding.

Now shift to the other side. Think about the previous questions, and try to chart what your body gut is saying.

While you may not get a gut answer at first, if you come back with the question several times, you'll likely hear just what your gut wants you to know.